-
1
-
-
9644262514
-
Rapid determination of five probe drugs and their metabolites in human plasma and urine by liquid chromatography/tandem mass spectrometry: Application to cytochrome P450 phenotyping studies [J]
-
Yin OQ, Lam SS, Lo CM, et al. Rapid determination of five probe drugs and their metabolites in human plasma and urine by liquid chromatography/tandem mass spectrometry: application to cytochrome P450 phenotyping studies [J]. Rapid Commun Mass Spectrom, 2004,18: 2921-2933.
-
(2004)
Rapid Commun Mass Spectrom
, vol.18
, pp. 2921-2933
-
-
Yin, O.Q.1
Lam, S.S.2
Lo, C.M.3
-
2
-
-
27644596457
-
Predicting in vivo drug interactions from in vitro drug discovery data [J]
-
Wienkers LC, Heath TG. Predicting in vivo drug interactions from in vitro drug discovery data [J]. Nat Rev Drug Discov, 2005,4:825-833.
-
(2005)
Nat Rev Drug Discov
, vol.4
, pp. 825-833
-
-
Wienkers, L.C.1
Heath, T.G.2
-
3
-
-
0033997634
-
Automated high throughput human CYP isoform activity assay using SPE-LC/MS method; application in CYP inhibition evaluation [J]
-
Yin H, Racha J, Li SY, et al. Automated high throughput human CYP isoform activity assay using SPE-LC/MS method; application in CYP inhibition evaluation [J]. Xenobiotica, 2000,30:141-154.
-
(2000)
Xenobiotica
, vol.30
, pp. 141-154
-
-
Yin, H.1
Racha, J.2
Li, S.Y.3
-
4
-
-
0033811314
-
High-throughput cytochrome P450 (CYP) inhibition screening via cassette probe-dosing strategy. I. Development of direct injection/ on-line guard cartridge extraction/tandem mass spectrometry for the simultaneous detection of CYP probe substrates and their metabolites [J]
-
Bu HZ, Magis L, Knuth K, et al. High-throughput cytochrome P450 (CYP) inhibition screening via cassette probe-dosing strategy. I. Development of direct injection/ on-line guard cartridge extraction/tandem mass spectrometry for the simultaneous detection of CYP probe substrates and their metabolites [J]. Rapid Commun Mass Spectrom, 2000,14:1619-1624.
-
(2000)
Rapid Commun Mass Spectrom
, vol.14
, pp. 1619-1624
-
-
Bu, H.Z.1
Magis, L.2
Knuth, K.3
-
5
-
-
0035157254
-
A method for the simultaneous evaluation of the activities of seven major human drug-metabolizing cytochrome P450s using an in vitro cocktail of probe substrates and fast gradient liquid chromatography tandem mass spectrometry [J]
-
Dierks EA, Stams KR, Lim HK, et al. A method for the simultaneous evaluation of the activities of seven major human drug-metabolizing cytochrome P450s using an in vitro cocktail of probe substrates and fast gradient liquid chromatography tandem mass spectrometry [J]. Drug Metab Dispos, 2001,29:23-29.
-
(2001)
Drug Metab Dispos
, vol.29
, pp. 23-29
-
-
Dierks, E.A.1
Stams, K.R.2
Lim, H.K.3
-
6
-
-
0037175449
-
Rapid and quantitative determination of metabolites from multiple cytochrome P450 probe substrates by gradient liquid chromatography-electrospray ionization-ion trap mass spectrometry [J]
-
Zhang T, Zhu Y, Gunaratna C. Rapid and quantitative determination of metabolites from multiple cytochrome P450 probe substrates by gradient liquid chromatography-electrospray ionization-ion trap mass spectrometry [J]. J Chromatogr B, 2002,780:371-379.
-
(2002)
J Chromatogr B
, vol.780
, pp. 371-379
-
-
Zhang, T.1
Zhu, Y.2
Gunaratna, C.3
-
7
-
-
0037212558
-
High-throughput inhibition screening of major human cytochrome P450 enzymes using an in vitro cocktail and liquid chromatography-tandem mass spectrometry [J]
-
Testino SA, Patonay G. High-throughput inhibition screening of major human cytochrome P450 enzymes using an in vitro cocktail and liquid chromatography-tandem mass spectrometry [J]. J Pharm Biomed Anal, 2003, 30:1459-1467.
-
(2003)
J Pharm Biomed Anal
, vol.30
, pp. 1459-1467
-
-
Testino, S.A.1
Patonay, G.2
-
8
-
-
4644223218
-
Simultaneous determination of the inhibitory potency of herbal extracts on the activity of six major cytochrome P450 enzymes using liquid chromatography/mass spectrometry and automated online extraction [J]
-
Unger M, Frank A. Simultaneous determination of the inhibitory potency of herbal extracts on the activity of six major cytochrome P450 enzymes using liquid chromatography/mass spectrometry and automated online extraction [J]. Rapid Commun Mass Spectrom, 2004, 18:2273-2281.
-
(2004)
Rapid Commun Mass Spectrom
, vol.18
, pp. 2273-2281
-
-
Unger, M.1
Frank, A.2
-
9
-
-
11144242471
-
Multiple P450 substrates in a single run: Rapid and comprehensive in vitro interaction assay [J]
-
Turpeinen M, Uusitalo J, Jalonen J, et al. Multiple P450 substrates in a single run: rapid and comprehensive in vitro interaction assay [J]. Eur J Pharm Sci, 2005,24: 123-132.
-
(2005)
Eur J Pharm Sci
, vol.24
, pp. 123-132
-
-
Turpeinen, M.1
Uusitalo, J.2
Jalonen, J.3
-
11
-
-
0017184389
-
A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding [J]
-
Bradford MM. A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding [J]. Anal Biochem, 1976,2:248-254.
-
(1976)
Anal Biochem
, vol.2
, pp. 248-254
-
-
Bradford, M.M.1
-
12
-
-
2442690439
-
Validated assays for human cytochrome P450 activities [J]
-
Walsky RL, Obach RS. Validated assays for human cytochrome P450 activities [J]. Drug Metab Dispos, 2004,32:647-660.
-
(2004)
Drug Metab Dispos
, vol.32
, pp. 647-660
-
-
Walsky, R.L.1
Obach, R.S.2
-
13
-
-
3042641177
-
An evaluation of the in vitro metabolism data for predicting the clearance and drug-drug interaction potential of CYP2C9 substrates [J]
-
Andersson TB, Bredberg E, Ericsson H, et al. An evaluation of the in vitro metabolism data for predicting the clearance and drug-drug interaction potential of CYP2C9 substrates [J]. Drug Metab Dispos, 2004,32: 715-721.
-
(2004)
Drug Metab Dispos
, vol.32
, pp. 715-721
-
-
Andersson, T.B.1
Bredberg, E.2
Ericsson, H.3
-
14
-
-
0035108902
-
High-throughput cytochrome P450 (CYP) inhibition screening via a cassette probe-dosing strategy. V. Validation of a direct injection/on-line guard cartridge extraction-tandem mass spectrometry method for CYP1A2 inhibition assessment [J]
-
Bu HZ, Knuth K, Magis L, et al. High-throughput cytochrome P450 (CYP) inhibition screening via a cassette probe-dosing strategy. V. Validation of a direct injection/on-line guard cartridge extraction-tandem mass spectrometry method for CYP1A2 inhibition assessment [J]. Eur J Pharm Sci, 2001,12:447-452.
-
(2001)
Eur J Pharm Sci
, vol.12
, pp. 447-452
-
-
Bu, H.Z.1
Knuth, K.2
Magis, L.3
-
15
-
-
0032711206
-
Determination of a 'GW cocktail' of cytochrome P450 probe substrates and their metabolites in plasma and urine using automated solid phase extraction and fast gradient liquid chromatography tandem mass spectrometry [J]
-
Scott RJ, Palmer J, Lewis IA, et al. Determination of a 'GW cocktail' of cytochrome P450 probe substrates and their metabolites in plasma and urine using automated solid phase extraction and fast gradient liquid chromatography tandem mass spectrometry [J]. Rapid Commun Mass Spectrom, 1999,13:2305-2319.
-
(1999)
Rapid Commun Mass Spectrom
, vol.13
, pp. 2305-2319
-
-
Scott, R.J.1
Palmer, J.2
Lewis, I.A.3
-
16
-
-
0142131213
-
The conduct of in vitro and in vivo drug-drug interaction studies: A PhRMA perspective [J]
-
Bjornsson TD, Callaghan JT, Einolf HJ, et al. The conduct of in vitro and in vivo drug-drug interaction studies: a PhRMA perspective [J]. J Clin Pharmcol, 2003,43:443-469.
-
(2003)
J Clin Pharmcol
, vol.43
, pp. 443-469
-
-
Bjornsson, T.D.1
Callaghan, J.T.2
Einolf, H.J.3
-
17
-
-
0037403747
-
Impact of nonspecific binding to microsomes and phospholipid on the inhibition of cytochrome P4502D6; implications for relating in vitro inhibition data to in vivo drug interactions [J]
-
Margolis JM, Obach RS. Impact of nonspecific binding to microsomes and phospholipid on the inhibition of cytochrome P4502D6; implications for relating in vitro inhibition data to in vivo drug interactions [J]. Drug Metab Dispos, 2003,31:606-611.
-
(2003)
Drug Metab Dispos
, vol.31
, pp. 606-611
-
-
Margolis, J.M.1
Obach, R.S.2
-
18
-
-
0036891924
-
Microsomal protein concentration modifies the apparent inhibitory potency of CYP3A inhibitors [J]
-
Tran TH, Von Moltke LL, Venkatakrishnan K, et al. Microsomal protein concentration modifies the apparent inhibitory potency of CYP3A inhibitors [J]. Drug Metab Dispos, 2002,30:1441-1445.
-
(2002)
Drug Metab Dispos
, vol.30
, pp. 1441-1445
-
-
Tran, T.H.1
Von Moltke, L.L.2
Venkatakrishnan, K.3
-
19
-
-
26844546679
-
Influence of cytochrom P450 CYP2C9 polymorphism on the pharmacokinetics of tolbutamide metabolism using oligonucleotide genotyping microarray [J]
-
Li J, Wen SY, Wang R, et al. Influence of cytochrom P450 CYP2C9 polymorphism on the pharmacokinetics of tolbutamide metabolism using oligonucleotide genotyping microarray [J]. Acta Pharm Sin, 2005, 40:695-699.
-
(2005)
Acta Pharm Sin
, vol.40
, pp. 695-699
-
-
Li, J.1
Wen, S.Y.2
Wang, R.3
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