Alkaloids of Crinum x powellii “Album” (Amaryllidaceae) and their Topoisomerase Inhibitory Activity

Zeitschrift fur Naturforschung - Section C Journal of Biosciences

Volumn 62, Issue 3-4, 2007, Pages 223-226

  Niño, Jaime ^a   Hincapié, Gina M ^a   Correa, Yaned M ^a   Mosquera, Oscar M ^a  

^a UNIVERSIDAD TECNOLÓGICA DE PEREIRA   (Colombia)

Author keywords

Amaryllidaceae Type Alkaloids; Mutant Yeast Assay; Saccharomyces cerevisiae

Indexed keywords

ALKALOID; AMARYLLIDACEAE ALKALOID; ANILINE DERIVATIVE; DNA TOPOISOMERASE; ENZYME INHIBITOR; ISMINE; LYCORINE; METHANOL; PHENANTHRIDINE DERIVATIVE; PLANT EXTRACT; UNCLASSIFIED DRUG;

ARTICLE; CHEMISTRY; CRINUM; DRUG ANTAGONISM; DRUG EFFECT; GENETICS; ISOLATION AND PURIFICATION; MUTAGENESIS; SACCHAROMYCES CEREVISIAE; THIN LAYER CHROMATOGRAPHY;

ALKALOIDS; AMARYLLIDACEAE ALKALOIDS; ANILINE COMPOUNDS; CHROMATOGRAPHY, THIN LAYER; CRINUM; DNA TOPOISOMERASES; ENZYME INHIBITORS; METHANOL; MUTAGENESIS; PHENANTHRIDINES; PLANT EXTRACTS; SACCHAROMYCES CEREVISIAE;

AMARYLLIDACEAE; CRINUM; SACCHAROMYCES CEREVISIAE;

EID: 34547398623     PISSN: 09395075     EISSN: None     Source Type: Journal    
DOI: 10.1515/znc-2007-3-411     Document Type: Article

References (21)

1. Baka S., Ranson M., Lorigan P., Danson S., Linton K., Hoogendam I., Mettinger K., and Thatcher N. (2005), A phase II trial with RFS2000 (rubitecan) in patients with advanced non-small cell lung cancer. Eur. J. Cancer 41, 1547-1550.
2. Baker J. T., Borris R. P., Carte B., Cordell G. A., Soe-jarto D. D., Cragg G. M., Gupta M. P., Iwu M. M., Madulid D. R., and Tyler V. E. (1995), Natural product drug discovery and development: new perspective on international collaboration. J. Nat. Prod. 58, 1325-1357.
3. Bastida J., Viladomat F., and Codina C. (1998), Narcissus alkaloids. In: Studies in Natural Products Chemistry (Atta-ur-Rhahman, ed.). Elsevier, Amsterdam, Vol. 20, pp. 323-405.
4. Cabezas F., Ramirez A., Viladomat F., Codina C., and Bastida J. (2003), Alkaloids from Eucharis amazónica (Amaryllidaceae). Chem. Pharm. Bull. 51, 315-317.
5. Di Francisco A. M., Riccardi A. S., Barone G., Rutella S., Meco D., Frapolli R., Zucchetti M., D'Incalci M., Pisano C., Carminati P., and Riccardi R. (2005), The novel lipophilic camptothecin analogue gimatecan is very active in vitro in human neuroblastoma: A comparative study with SN38 and topotecan. Biochem. Pharmacol. 70, 1125-1136.
6. Elgorashi E. E., Stafford G. I., and van Staden J. (2004), Acetylcholinesterase enzyme inhibitory effects of Amaryllidaceae alkaloids. Planta Med. 70, 260-262.
7. Etievant C., Kruczynski A., Barret J.-M., Perrin D., and Hill B. T. (2003), Apoptotic cell death induction by F 11782, a novel dual catalytic inhibitor of topoisomerase I and II. Biochem. Pharmacol. 65, 755-763.
8. Ghosal S., Saini K. S., and Razdan S. (1985), Crinum alkaloids: their chemistry and biology. Phytochemistry 24, 2141-2156.
9. Gunatilaka A. A. L. and Kingston D. G. I. (1998), DNA-damaging natural products with potential anticancer activity. In: Studies in Natural Products Chemistry (Atta-ur-Rhahman, ed.). Elsevier, Amsterdam, Vol. 20, pp. 457-505.
10. Gunatilaka A. A. L., Kingston D. G. I., and Johnson R. K. (1994), Mechanism-based isolation and structures of some anticancer active natural products. Pure Appl. Chem. 66, 2219-2222.
11. Hajji N., Mateos S., Pastor N., Dominguez I., and Cortes F. (2005), Induction of genotoxic and cytotoxic damage by aclarubicin, a dual topoisomerase inhibitor. Mutat. Res. Genet. Toxicol. Envir. Mutag. 583, 26-35.
12. Kudoh S., Nakamura S., Nakano T., Komuta K., Isobe T., Katakami N., Fukuda Y., Takada Y., Takada M., Fukuoka M., and Ariyoshi Y. (2005), Irinotecan and etoposide for previously untreated extensive-disease small cell lung cancer: a phase II trial of West Japan Thoracin Oncology Group. Lung Cancer 49, 263-269.
13. Kuo L. -M. Y., Chen K.-Y., Hwang S.-Y., Chen J.-L., Liu Y.-Y., Liaw C.-C., Ye P.-H., Chou C.-J., Shen C.-C., and Kuo Y.-H. (2005), DNA topoisomerase I inhibitor, ergosterol peroxide from Pénicillium oxalicum. Planta Med. 71, 77-79.
14. Liu J., Hu W.-X., He L.-F., Ye M., and Li Y. (2004), Effects of lycorine on HL-60 cells via arresting cell cycle and inducing apoptosis. FEBS Lett. 578, 245-250.
15. Rhee I. K., van de Meent M., Ingkaninan K., and Verpoorte R. (2001), Screening for acetylcholinesterase inhibitors from Amaryllidaceae using silica gel thin-layer chromatography in combination with bioactivity staining. J. Chromatogr. A 915, 217-223.
16. Rios J., Recio M., and Villar A. (1988), Screening methods for natural products with antimicrobial activity: A review of the literature. J. Ethnopharmacol. 23, 127-149.
17. Verpoorte R. (1998), Exploration of nature's chemodiversity: the role of secondary metabolites as leads in drug development. DDT 3, 232-238.
18. Viladomat F., Almanza G. R., Codina C., Bastida J., Campbell W. E., and Mathee S. (1996), Alkaloids from Brunsvigia orientalis. Phytochemistry 43, 1379-1384.
19. Yonezawa Y., Tsuzuki T., Eitsuka T., Miyazawa T., Hada T., Uryu K., Murakami-Nakai C., Ikawa H., Kuriyama I., Takemura M., Oshige M., Yoshida H., Sakaguchi K., and Mizushina Y. (2005), Inhibitory effect of conjugated eicosapentaenoic acid on human DNA topoisomerase I and II. Arch. Biochem. Biophys. 435, 197-206.
20. Yui S., Mikami M., Mimaki Y., Sashida Y., and Yamazaki M. (2001), Inhibition effect of Amaryllidaceae alkaloids, lycorine and lycoricidinol on macrophage TNF-a production. Yakugaku Zasshi 121, 167-171.
21. Zhou B., Johnson R. K., Mattern M., Wang X., Hecht S., Beck H., Ortiz A., and Kingston D. G. I. (2000), Isolation and biochemical characterization of a new topoisomerase inhibitor from Ocotea leucoxylum. J. Nat. Prod. 63, 217-221.