Regulation of HIF-1 α to expression of N-myc downstream regulated gene 1 in colorectal carcinoma

Wuhan University Journal of Natural Sciences

Volumn 12, Issue 3, 2007, Pages 563-568

  Zhao, Duanyi ^a   Liu, Zhisu ^a   Jiang, Congqing ^a   Bangoura, Gassimou ^a   Wu, Kailang ^a   Wu, Jianguo ^a  

^a WUHAN UNIVERSITY   (China)

Author keywords

Colorectal carcinoma; Hypoxia inducible factor 1 (HIF 1 ); N myc downstream regulated gene 1; Small interfering RNA

Indexed keywords

EID: 34547368110     PISSN: 10071202     EISSN: None     Source Type: Journal    
DOI: 10.1007/s11859-006-0105-2     Document Type: Article

References (12)

1. Jiang C Q, Liu Z S, Fan L F, et al. Expression Levels and Significance of Hypoxia Inducible Factor-1 Alpha and Vascular Endothelial Growth Factor in Human Colorectal Adenocarcinoma [J].Chin Med J, 2004, 117:1541-1546.
2. Zhen W, Fang W, Wang W, et al. Correlation of N-myc Downstream-Regulated Gene 1 Overexpression with Progressive Growth of Colorectal Neoplasm[J]. World J Gastroenterol, 2004, 10:550-554
3. Cangul H, Salnikow K, Yee H, et al. Enhanced Overexpression of an HIF-1/Hypoxia-Related Protein in Cancer Cells[J]. Environ Health Perspect, 2002, 110:783-788.
4. Zhang Q, Zhang Z F, Rao J Y et al. Treatment with siRNA and Antisense Oligonucleotides Targeted to HIF-Lalpha Induced Apoptosis in Human Tongue Squamous Cell Carcinomas[J]. Int J Cancer, 2004, 111:849-857.
5. Sowter H M, Raval R, Moore J, et al. Predominant Role of Hypoxia-Inducible Transcription Factor (Hif)-1 α Versus Hif-2 α in Regulation of the Transcriptional Response to Hypoxia[J].Cancer Res, 2003, 63:6130-6134.
6. Berchner U H, HPetrat F H, Doege K H, et al. Chelation of Cellular Calcium Modulates Hypoxia-Inducible Gene Expression Through Activation of Hypoxia-Inducible Factor-Lalpha[J]. J Biol Chem, 2004, 279:44976-44986.
7. Van Beizen N, Dinjens W N, Diesveld M P, et al. A Novel Gene Which is Up-Regulated During Colon Epithelial Cell Differentiation and Down-Regulated in Colorectal Neoplasms[J]. Lab Invest, 1997, 77:85-92.
8. Salnikow K, Davidson T, Zhang Q, et al. The Involvement of Hypoxia-Inducible Transcription Factor-1-Dependent Pathway in Nickel Carcinogenesis[J]. Cancer Res, 2003, 63:3524-3530.
9. Han Y H,Xia L,Song L P,et al. Comparative Proteomic Analysis of Hypoxia-Treated and Untreated Human Leukemic U937 Cells[J]. Proteomics, 2006, 6:3262-3274.
10. Cangul H. Hypoxia Upregulates the Expression of NDRG1 Gene Leading to Its Overexpression in Various Human Cancers[J]. BMC Genet, 2004, 5:27.
11. Chang J T, Wang H M, Chang K W, et al. Identification of Differentially Expressed Genes in Oral Squamous Cell Carcinoma (OSCC):Overexpression of NPM, CDK1 and NDRG1 and Underexpression of CHES1[J]. Int J Cancer, 2005, 114:942-949.
12. Shah M A, Kemeny N, Hummer A, et al. Drg1 Expression in 131 Colorectal Liver Metastases: Correlation with Clinical Variables and Patient Outcomes[J]. Clin Cancer Res, 2005, 11:3296-3302.