Effect of inulin supplementation on selected gastric, duodenal, and caecal microbiota and short chain fatty acid pattern in growing piglets

Archives of Animal Nutrition

Volumn 61, Issue 4, 2007, Pages 235-246

  Eberhard, Markus ^a   Hennig, Ulf ^a   Kuhla, Siegfried ^a   Brunner, Ronald M ^a   Kleessen, Brigitta ^b   Metges, Cornelia C ^a  

^a LEIBNIZ INSTITUTE FOR FARM ANIMAL BIOLOGY FBN   (Germany)

^b UNIVERSITY OF LEIPZIG   (Germany)

Author keywords

Intestinal microbiota; Inulin; Pig; Short chain fatty acids

Indexed keywords

INULIN; VOLATILE FATTY ACID;

ANIMAL; ANIMAL DISEASE; ANIMAL FOOD; ARTICLE; BACTERIAL COUNT; BACTERIUM; BIFIDOBACTERIUM; CECUM; DIET SUPPLEMENTATION; DOSE RESPONSE; DRUG EFFECT; DUODENUM; FLUORESCENCE IN SITU HYBRIDIZATION; GROWTH, DEVELOPMENT AND AGING; INTESTINE; LACTOBACILLUS; MALE; METABOLISM; MICROBIOLOGY; NEWBORN; RANDOMIZATION; STOMACH; SWINE; WEIGHT GAIN;

ANIMAL FEED; ANIMAL NUTRITION PHYSIOLOGY; ANIMALS; ANIMALS, NEWBORN; BACTERIA; BIFIDOBACTERIUM; CECUM; COLONY COUNT, MICROBIAL; DIETARY SUPPLEMENTS; DOSE-RESPONSE RELATIONSHIP, DRUG; DUODENUM; FATTY ACIDS, VOLATILE; IN SITU HYBRIDIZATION, FLUORESCENCE; INTESTINES; INULIN; LACTOBACILLUS; MALE; RANDOM ALLOCATION; STOMACH; SWINE; WEIGHT GAIN;

BACTERIA (MICROORGANISMS); CLOSTRIDIUM; ENTEROBACTERIACEAE; ENTEROCOCCUS; LACTOBACILLUS; SUIDAE;

EID: 34547244048     PISSN: 1745039X     EISSN: 14772817     Source Type: Journal    
DOI: 10.1080/17450390701431631     Document Type: Article

References (48)

1. Amann RI, Ludwig W, Schleifer KH. 1995. Phylogenetic identification and in situ detection of individual microbial cells without cultivation. Microbiol Rev 59:143-169.
2. Annison G, Topping DL. 1994. Nutritional role of resistant starch: chemical structure vs. physiological function. Ann Rev Nutr 14:297-320.
3. Bach Knudsen KE, Hessov I. 1995. Recovery of inulin from Jerusalem artichoke (Helianthus tuberosus L.) in the small intestine of man. Brit J Nutr 74:101-113.
4. Bach Knudsen KE, Jensen BB, Hansen I. 1993. Digestion of polysaccharides and other major components in the small and large intestine of pigs fed on diets consisting of oat fractions rich in β-D-glucan. Brit J Nutr 70:537-556.
5. Beimfohr C, Krause A, Amann RI, Ludwig W, Schleifer KH. 1993. In situ identification of lactobacilli, enterococci and streptococci. Syst Appl Micro 16:450-456.
6. Böhmer BM, Branner GR, Roth-Maier DA. 2005. Precaecal and faecal digestibility of inulin (DP 10-12) or an inulin/Enterococcus faecium mix and effects on nutrient digestibility and microbial gut flora. J Anim Physiol Anim Nutr 89:388-396.
7. Branner GR, Böhmer BM, Erhardt W, Henke J, Roth-Maier DA. 2004. Investigation on the precaecal and faecal digestibility of lactulose and inulin and their influence on nutrient digestibility and microbial characteristics. Arch Anim Nutr 58:353-366.
8. Brown I, Warhust M, Arcot J, Playne M, Illman RJ, Topping DL. 1997. Fecal numbers of bifidobacteria are higher in pigs fed Bifidobacterium longum with a high amylose cornstarch than with low amylose cornstarch. J Nutr 127:1822-1827.
9. Davis SS, Ilium L, Hinchcliffe M. 2001. Gastrointestinal transit of dosage forms in the pig. J Pharm Pharmacol 53:33-39.
10. De Schrijver R, De Vos S. 2003. Effects of dietary supplemented oligosaccharides on digestion in ileal cannulated pigs. In: Proc 9th Intern Symp Digestive Physiology in Pigs, Banff, AB, Canada: University of Alberta, Edmonton, Canada, pp 274-276.
11. Drew MD, Van Kessel AG, Estrada AE, Ekpe ED, Zijlstra RT. 2002. Effect of dietary cereal on intestinal bacterial populations in weaned pigs. Can. J Anim Sci 82:607-609.
12. Ducluzeau R. 1985. Implantation and development of the gut flora in the newborn pigiet. Pig News Inform 6:415-418.
13. Duncan SH, Holtrop G, Lobley GE, Calder AG, Stewart CS, Flint HJ. 2004. Contribution of acetate to butyrate formation by human faecal bacteria. Brit J Nutr 91:915-923.
14. Ellegård L, Andersson H, Bosaeus I. 1997. Inulin and oligofructose do not influence the absorption of cholesterol, or the excretion of cholesterol, Ca, Mg, Zn, Fe, or bile acids but increases energy excretion in ileostomy subjects. Eur J Clin Nutr 51:1-5.
15. Farnworth ER, Midler HW, Jones JD, Cave N, Yamazaki H, Rao AV. 1992. Feeding Jerusalem artichoke flour rich in fructooligosaccharides to weanling pigs. Can J Anim Sci 72:977-980.
16. Franks AH, Harmsen HJ, Raangs GC, Jansen GJ, Schut F, Welling GW. 1998. Variations of bacterial populations in human feces measured by fluorescent in situ hybridization with group-specific 16S rRNA-targeted oligonucleotide probes. Appl Environ Microbiol 64:3336-3345.
17. Franklin MA, Mathew AG, Vickers JR, Clift RA. 2002. Characterization of microbial populations and volatile fatty acid concentrations in the jejunum, ileum and cecum of pigs weaned at 17 vs. 24 days of age. J Anim Sci 80:2904-2920.
18. Gibson GR, Probert HM, Van Loo J, Rastall RA, Roberfroid MB. 2004. Dietary modulation of the human colonic microbiota: updating the concept of prebiotics. Nutr Res Rev 17:259-275.
19. Haacker K, Block HJ, Weissbach F. 1983. Zur kolorimetrischen Milchsäurebestimmung in Silagen mit p-Hydroxydiphenyl. Arch Anim Nutr 33:505-512.
20. Herich R, Revajova V, Levkut M, Bomba A, Nemcova R, Guba P, Gancarcikova S. 2002. The effect of Lactobacillus paracasei and Raftilose P95 upon the non-specific immune response of piglets. Food Agric Immunol 14:171-179.
21. Houdijk JG, Hartemink R, Van Laere KM, Williams BA, Bosch MW, Verstegen MW, Tamminga S. 1997. Fructooligosaccharides and transgalactooligosaccharides in weaner pigs' diet. In: Proc Intern Symp: Non-digestible oligosaccharides: Healthy food for the colon? 4-5 December 1997. Wageningen, The Netherlands: Wageningen Academic Publishers, pp 69-78.
22. Houdijk JG, Hartemink R, Verstegen MW, Bosch MW. 2002. Effects of dietary non-digestible oligosaccharides on microbial characteristics of ileal chyme and faeces in weaner pigs. Arch Anim Nutr 56:297-307.
23. Jensen BB. 1993. The possibility of manipulating the microbial activity in the digestive tract of monogastric animals. In: Proc 44th Annual Meeting of the European Association for Animal Production. 16-19 August 1993. Aarhus, Denmark.
24. Jensen BB, Jorgensen H. 1994. Effect of dietary fiber on microbial activity and microbial gas production in various regions of the gastrointestinal tract of pigs. Appl Environ Microbiol 60:1897-1904.
25. Jensen BB. 2001. Possible ways of modifying type and amount of products from microbial fermentation in the gut. In: Piva A, Bach Knudsen KE, Lindberg JE, editors. Gut environment of pigs. Nottingham; Nottingham Press. pp 181-200.
26. Kleessen B, Hartmann L, Blaut M. 2001. Oligofructose and long-chain inulin: Influence on the gut microbial ecology of rats associated with a human faecal flora. Brit J Nutr 86:291-300.
27. Kruse HP, Kleessen B, Blaut M. 1999. Effects of inulin on faecal bifidobacteria in human subjects. Brit J Nutr 82:375-382.
28. Langendijk PS, Schut F, Jansen GJ, Raangs GC, Kamphuis GR, Wilkinson MH, Welling GW. 1995. Quantitative fluorescence in situ hybridization of Bifidobacterium spp. with genus-specific 16S rRNA-targeted probes and its application in fecal samples. Appl Environ Microbiol 61:3069-3075.
29. Latymer EA, Low AG, Fadden K, Sambrook IE, Woodley SC, Keal HD. 1990. Measurement of transit time of digesta through sections of gastrointestinal tract of pigs fed with diets containing various sources of dietary fibre (non-starch polysaccharides). Arch Anim Nutr 40:667-680.
30. Leser TD, Amenuvor JZ, Jensen TK, Lindecrona RH, Boye M, Moller K. 2002. Culture-independent analysis of gut bacteria: The pig gastrointestinal tract microbiota revisited. Appl Environ Microbiol 68:673-690.
31. Loh G, Eberhard M, Brunner R, Hennig U, Kuhla S, Kleessen B, Metges GC. 2006. Inulin alters the intestinal microbiota and short-chain fatty acid concentrations in growing pigs regardless of their basal diet. J Nutr 136:1198-1202.
32. Macfarlane GT, Cummings JH. 1999. Probiotics and prebiotics: Can regulating the activities of intestinal bacteria benefit health? BMJ 318:999-1003.
33. Mikkelsen LL. 2001. Fructooligosaccharides and galactosaccharides as prebiotics for piglets at weaning: Effect on the intestinal microbial ecosystem with emphasis on the population on bifidobacteria [dissertation]. The Royal Veterinary and Agricultural University Frederiksberg, Denmark.
34. Mikkelsen LL, Jensen BB. 2004. Effect on fructo-oligosaccharides and transgalacto-oligosaccharides on microbial populations and microbial activity in the gastrointestinal tract of piglets post-weaning. Anim Feed Sci Technol 117:107-119.
35. Naumann C, Bassler R. 1993. Die chemische Untersuchung von Futtermitteln. Methodenbuch 3, Ergänzungslieferung, Darmstadt: VDLUFA-Verlag, Germany.
36. Nilsson U, Bjorck I. 1988. Availability of cereal fructans and inulin in the rat intestinal tract. J Nutr 118:1482-1486.
37. Oli MW, Petschow BW, Buddington RK. 1998. Evaluation of fructooligosaccharide supplementation of oral electrolyte solutions for treatment of diarrhea: Recovery of the intestinal bacteria. Dig Dis Sci 43:138-147.
38. Poulsen LK, Licht TR, Rang C, Krogfelt KA, Molin S. 1995. Physiological state of Escherichia coli BJ4 growing in the large intestines of streptomycin-treated mice. J Bacteriol 177:5840-5845.
39. Roberfroid M. 2005. Introducing inulin-type fructans. Brit J Nutr 93(Suppl. 1):13-25.
40. Scheppach W. 1994. Effects of short chain fatty acids on gut morphology and function. Gut 35:35-38.
41. Schulze F, Bathke W. 1976. Quantitative composition of the gastrointestinal flora in the young pig. Arch Exp Veterinarmed 31:161-185.
42. Sghir A, Chow JM, Mackie RI. 1998. Continuous culture selection of bifidobacteria and lactobacilli from human faecal samples using fructooligosaccharide as selective substrate. J Appl Microbiol 85:769-777.
43. Steegmans M, Ilianes S, Hoebregs H. 2004. Enzymatic, spectrophotometric determination of glucose, fructose, sucrose and inulin/oligofructose in foods. J AOAC Int 87:1200-1207.
44. Stölken B, Schumann W, Bolduan G, Hackl W. 1997. β-Glucane und Pentosane in Getreidesortimenten aus Mecklenburg-Vorpommern. Proc VDLUFA congress 1996. Darmstadt: VDLUFA-Schriftenreihe 44:241-244.
45. Tannock GW, Munro K, Bibiloni R, Simon MA, Hargreaves P, Gopal P, Harmsen H, Welling G. 2004. Impact of consumption of oligosaccharide-containing biscuits on the fecal microbiota of humans. Appl Environ Microbiol 70:2129-2136.
46. Topping DL, Clifton PM. 2001. Short-chain fatty acids and human colonie function: Roles of resistant starch and nonstarch polysaccharides. Physiol Rev 81:1031-1064.
47. Van Laere KM, Bosveld M, Schols HA, Beldman G, Voragen AG. 1997. Fermentative degradation of plant cell wall derived oligosaccharides by intestinal bacteria. In: Hartemink R, editor. Proceedings of the International Symposium 'Non-digestible oligosaccharides: Healthy food for the colon?" Wageningen, The Netherlands. Wageningen Academic Publishers, pp 37-46.
48. White LA, Newman MC, Cromwil GL, Lindemann MD. 2002. Brewers dried yeast as a source of mamman oligosaccharides for weanling pigs. J Anim Sci 80:2619-2628.