Temperature dependence of skin permeability to hydrophilic and hydrophobic solutes

Journal of Pharmaceutical Sciences

Volumn 96, Issue 7, 2007, Pages 1832-1839

  Mitragotri, Samir ^a  

^a University of California   (United States)

Author keywords

Activation; Hydrophilic; Hydrophobic; Skin; Temperature; Transdermal

Indexed keywords

2 BUTANONE; 2 CHLOROPHENOL; 2 NAPHTHOL; 3 NITROPHENOL; ACETYLSALICYLIC ACID; ALCOHOL; BETAHISTINE; BUTANOL; BUTYL PARABEN; CAFFEINE; CARBON DISULFIDE; CHLOROCRESOL; CORTICOSTERONE; ESTRADIOL; ETHER; FLUOROURACIL; GLYCOPYRRONIUM BROMIDE; HEPTANOL; HEXANOL; IBUPROFEN; IMIPRAMINE; INDOMETACIN; KETOPROFEN; MANNITOL; META CRESOL; METHANOL; METHYL PARABEN; PARA CRESOL; TETRYLAMMONIUM; ZIDOVUDINE;

ARTICLE; HYDROPHILICITY; HYDROPHOBICITY; LIPOPHILICITY; SKIN PERMEABILITY; SOLUTE; STRATUM CORNEUM; TEMPERATURE DEPENDENCE; THEORETICAL MODEL;

EID: 34547230179     PISSN: 00223549     EISSN: 15206017     Source Type: Journal    
DOI: 10.1002/jps.20793     Document Type: Article

References (30)

1. Roberts MS, Anderson RA, Swarbrick J, Moore DE. 1978. The percutaneous absorption of phenolic compounds: The mechanism of diffusion across the stratum corneum. J Pharm Pharmacol 30: 486-490.
2. Scheuplein RJ, Blank IH. 1971. Permeability of the skin. Physiol Rev 51:702-747.
3. Peck KD, Ghanem AH, Higuchi WL 1995. The effect of temperature upon the permeation of polar and ionic solutes through human epidermal membrane. J Pharm Sci 84:975-982.
4. Durrheim H, Flynn GL, Higuchi WI, Behl CR. 1980. Permeation of Hairless Mouse Skin I: Experimental Methods and Comparison with Human Epidermal Permeation by Alkanols. J Pharm Sci 69:781-786.
5. Johnson ME, Blankschtein D, Lange R. 1997. Evaluation of solute permeation through the stratum corneum; lateral diffusion as the primary transport mechanism. J Pharm Sci 86(10):1162-1172.
6. Mitragotri S. 2003. Modeling skin permeability to hydrophilic and hydrophobic solutes based on four permeation pathways. J Control Rel 86:69-92.
7. Mitragotri A. 2002. Theoretical Analysis of Permeation of Small Hydrophobic Solutes across the Stratum Corneum based on Scaled Particle Theory. J Pharm Sci 91:744-752.
8. Mitragotri S. 2002. A theoretical analysis of permeation of small hydrophobic solutes across the stratum corneum based on Scaled Particle Theory. J Pharm Sci 91:744-752.
9. Hatfield RM, Fung LW. 1995. Molecular Properties of a Stratum Cornuem Model Lipid System: Large Unilamellar Vesicles. Biophys J 68:196-207.
10. Kasting GB, Barai ND, Wang TF, Nitsche JM. 2003. Mobility of water in human stratum corneum. J Pharm Sci 92:2326-2340.
11. Tang H, Mitragotri S, Blankschtein D, Langer R. 2001. Theoretical description of transdermal transport of hydrophilic permeants: Application to low-frequency sonophoresis. J Pharm Sci 90:545-568.
12. Tezel A, Sens A, Mitragotri S. 2003. Description of transdermal transport of hydrophilic solutes during low-frequency sonophoresis based on a modified porous pathway model. J Pharm Sci 92:381-393.
13. Deen W. 1987. Hindered transport of large molecules in liquid-filled pores. AIChE J 33:1409-1425.
14. Kasting GB, Smith RL, Cooper ER. 1987. Effect of lipid solubility and molecular size on percutaneous absorption. Pharmacol Skin 1:138-153.
15. Potts RO, Guy RH. 1995. A predictive algorithm for skin permeability: The effects of molecular size and hydrogen bond activity. Pharm Res 12:1628-1633.
16. Potts RO, Guy RH. 1992. Predicting skin permeability. Pharm Res 9:663-669.
17. Narishetty ST, Panchagnula R. 2004. Transdermal delivery of zidovudine: Effect of terpenes and their mechanism of action. J Control Rel 95:367-379.
18. Ogiso T, Ogiso H, Paku T, Iwaki M. 1996. Phase Transitions of Rat Stratum Corneum Lipids by an Electron Paramagnetic Resonance Study and Relationship of Phase States to Drug Penetration. Biochim Biophys Acta 1301:97-104.
19. Akomeah F, Nazir T, Martin GP, Brown MB. 2004. Effect of heat on the percutaneous absorption and skin retention of three model penetrants. Eur J Pharm Sci 21:337-345.
20. Xu X, Weisel CP. 2005. Dermal uptake of chloroform and haloketones during bathing. J Expo Anal Environ Epidemiol 15:289-296.
21. Meidan VM, Walmsley AD, Docker MF, Irwin WJ. 1999. Ultrasound-enhanced diffusion into coupling gel during phonophoresis of 5-fluorouracil. Int J Pharm 185:205-213.
22. Cornwell PA, Barry BW. 1994. Sesquiterpene components of volatile oils as skin penetration enhancers for the hydrophilic permeant 5-fluorouracil. J Pharm Pharmacol 46:261-269.
23. Ito Y, Ogiso T, Iwaki M. 1988. Thermodynamic Study on Enhancement of Percutaneous Penetration of Drugs by Azone. J Pharmacobio-Dyn 11: 749-757.
24. Jain AK, Panchagnula R. 2003. Effect of temperature on imipramine hydrochloride permeation: Role of lipid bilayer arrangement and chemical composition of rat skin. Int J Pharm 250:287-293.
25. Cornwell PA, Barry BW. 1993. The routes of penetration of ions and -fluorouracil across human skin and the mechanisms of action of terpene skin penetration enhancers. Int J Pharm 94:189-194.
26. Ohara N, Takayama K, Machida Y, Nagai T. 1994. Combined effect of d-limonene and temperature on the skin permeation of ketoprofen. Int J Pharm 105:31-38.
27. Hatcher ME, Plachy WZ. 1993. Dioxygen diffusion in the stratum corneum; an EPR SPin Label Study. Biochim Biophys Acta 1149:73-78.
28. Liron Z, Cohen S. 1984. Percutaneous absorption of alkanoic acids I: A study of operational conditions. J Pharm Sci 73:534-537.
29. Potts R, Francoeur ML. 1990. Lipid biophysics of water loss through the skin. Proc Natl Acad Sci 87:3871-3873.
30. Golden G, et al. 1987. Stratum cornuem lipid phase transisitions and Water Barrier Properties. Biochemistry 26:2382-2388.