Deracemization of quaternary stereocenters by Pd-catalyzed enantioconvergent decarboxylative allylation of racemic β-ketoesters

Angewandte Chemie - International Edition

Volumn 44, Issue 42, 2005, Pages 6924-6927

  Mohr, Justin T ^a   Behenna, Douglas C ^a   Harned, Andrew M ^a   Stoltz, Brian M ^a  

^a California Institute of Technology   (United States)

Author keywords

Allylation; Asymmetric catalysis; Enolates; Palladium

Indexed keywords

CARBON; CHEMICAL BONDS; ESTERS; STEREOCHEMISTRY;

ASYMMETRIC CATALYSIS; CASCADE REACTION; ENOLATES;

REACTION KINETICS;

ESTER; KETONE; ORGANOMETALLIC COMPOUND; PALLADIUM;

ALKYLATION; ARTICLE; CATALYSIS; CHEMICAL STRUCTURE; CHEMISTRY; DECARBOXYLATION; STEREOISOMERISM; SYNTHESIS;

ALKYLATION; CATALYSIS; DECARBOXYLATION; ESTERS; KETONES; MOLECULAR STRUCTURE; ORGANOMETALLIC COMPOUNDS; PALLADIUM; STEREOISOMERISM;

EID: 27544451620     PISSN: 14337851     EISSN: None     Source Type: Journal    
DOI: 10.1002/anie.200502018     Document Type: Article

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32. 3 was used as the ligand for the conversion of (±)-13 into (±)-14 and the meso isomer of 14 (not shown), a diastereomeric ratio of 70:30 was observed.