Effects of microcystin-LR on mouse lungs

Toxicon

Volumn 50, Issue 3, 2007, Pages 330-338

  Soares, Raquel M ^a   Cagido, Viviane R ^a   Ferraro, Rodrigo B ^a   Meyer Fernandes, José Roberto ^a   Rocco, Patrícia R M ^a   Zin, Walter A ^a   Azevedo, Sandra M F O ^a  

^a FEDERAL UNIVERSITY OF RIO DE JANEIRO   (Brazil)

Author keywords

Alveolar collapse; Inflammation; Lung; Microcystin LR

Indexed keywords

CYANOGINOSIN; CYANOGINOSIN LR; PHOSPHOPROTEIN PHOSPHATASE 1; PHOSPHOPROTEIN PHOSPHATASE 2A;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BREATHING MECHANICS; CELL INFILTRATION; CONTROLLED STUDY; ENZYME ACTIVITY; ENZYME INHIBITION; HISTOLOGY; INFLAMMATION; INFLAMMATORY CELL; LUNG; LUNG ALVEOLUS CELL; LUNG COLLAPSE; LUNG EDEMA; MALE; MOUSE; NONHUMAN; PRIORITY JOURNAL; VISCOELASTICITY;

ANIMALS; LUNG; LUNG DISEASES; MALE; MICE; MICROCYSTINS; NEUTROPHILS; TIME FACTORS;

CYANOBACTERIA; MUS;

EID: 34547163002     PISSN: 00410101     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.toxicon.2007.04.003     Document Type: Article

References (42)

1. An J., and Carmichael W.W. Use of a olorimetric protein phosphatase inhibition assay and enzyme linked immunosorbent assay for the study of microcystins and nodularins. Toxicon 32 12 (1994) 1495-1507
2. Azevedo S.M.F.O., Carmichael W.W., Jochimsen E.M., Rinehart K.L., Lau S., Shaw G.R., and Eaglesham G.K. Human intoxication by microcystins during renal dialysis treatment in Caruaru-Brazil. Toxicology 181 (2002) 441-446
3. Bates J.H., Rossi A., and Milic-Emili J. Analysis of the behavior of the respiratory system with constant inspiratory flow. J. Appl. Physiol. 58 (1985) 1840-1848
4. Bates J.H.T., Ludwig M.S., Sly P.D., Brown K.A., Martin J.G., and Fredberg J.J. Interrupter resistance elucidated by alveolar pressure measurement in open-chest normal dogs. J. Appl. Physiol. 65 (1988) 408-414
5. Botha N., Venter M.V., Downing T.G., Shephard E.G., and Gehringer M.M. The effect of intraperitoneally administered microcystin-LR on gastrointestinal tract of Balb/c mice. Toxicon 43 (2004) 251-254
6. Carmichael W.W. The toxins of cyanobacteria. Sci. Am. 270 (1994) 78-86
7. Carmichael W.W., and An J.S. Using an enzyme linked immunosorbent assay (ELISA) and a protein phosphatase inhibition assay (PPIA) for the detection of microcystins and nodularins. Nat. Toxins 7 6 (1999) 377-385
8. Carmichael W.W., Azevedo S.M.F.O., An J., Molica R.J.R., Jochimsen E.M., Lau S., Rinehart K.L., Shaw G.R., and Eaglesham G.K. Human fatalities from cyanobacteria: chemical and biological evidence for cyanotoxins. Environ. Health Perspect. 109 (2001) 663-668
9. In: Chorus I., and Bartram J. (Eds). Toxic Cyanobacteria in Water-A Guide to Their Public Health Consequences, Monitoring and Management (1999), E & FN Spon., London 416pp
10. Chu F.S., Huang X., and Wei R.D. Enzyme-linked immunosorbent assay for microcystins in blue-green algal blooms. J. Assoc. Anal. Chem. 7 (1990) 451-454
11. Faffe D.S., Seidl V.R., Chagas P.S.C., Moraes V.L.G., Capelozzi V.L., Rocco P.R.M., and Zin W.A. Respiratory effects of lipopolysaccharide-induced inflammatory lung injury in mice. Eur. Respir. J. 15 (2000) 85-91
12. Falconer I.R., Smith J.V., Jackson A.R.B., Jones A., and Runnegar M.T.C. Oral toxicity of a bloom of the cyanobacterium Microcystis aeruginosa administered to mice over periods up to 1 year. J. Toxicol. Environ. Health 24 (1988) 291-305
13. Ferrão-Filho A.S., and Azevedo S.M.F.O. Effects of unicellular and colonial forms of toxic Microcystis aeruginosa from laboratory cultures and natural populations on tropical cladocerans. Aquat. Ecol. 37 (2002) 23-35
14. Francis G. Poisonous Australian lake. Nature 18 (1878) 11-12
15. Gundersen H.J.G., Bendtsen T.F., Korbo L., Marcussen N., Moller A., Nielsen K., Nyengaard J.R., Pakkenberg B., Sorensen F.B., Vesterby A., and West M.J. Some new, simple and efficient seterological methods and their use in pathological research and diagnosis. APMIS 96 (1988) 379-394
16. Humpage A.R., Hardy S.J., Moore E.J., Froscio S.M., and Falconer I.R. Microcystins (cyanobacterial toxins) in drinking water enhance the growth of aberrant crypt foci in the mouse colon. J. Toxicol. Environ. Health 61 (2000) 155-165
17. Ito E., Kondo F., and Harada K.-I. First report on the distribution of orally administered microcystin-lr in mouse tissue using an immunostaining method. Toxicon 38 (2000) 37-48
18. Ito E., Kondo F., and Harada K.-I. Intratracheal administration of microcystin-LR and its distribution. Toxicon 39 (2001) 265-271
19. Jochimsen E.M., Carmichael W.W., An J.S., Cardo D.M., Cookson S.T., Holmes C.E.M., Antunes M.B.C., Melo-Filho D.A., Lyra T.M., Barreto V.S.T., Azevedo S.M.F.O., and Jarvis W.R. Liver failure and death after exposure to microcystins at a haemodialysis center in Brazil. New Engl. J. Med. 33 (1998) 873-878
20. Klaassen C.D. Cassarett and Doull`s Toxicology: The Basic Science of Poisons. fifth ed (1996), Health Professions Division, McGraw-Hill 1211pp
21. Kochi T., Okubo S., Zin W.A., and Milic-Emili J. Flow and volume dependence of pulmonary mechanics in anesthetized cats. J. Appl. Physiol. 64 (1988) 441-450
22. Menezes S.L.S., Bozza P.T., Neto H.C.C.F., Laranjeira A.P., Negri E.M., Capelozzi V.L., Zin W.A., and Rocco P.R.M. Pulmonary and extrapulmonary acute lung injury: inflammatory and ultrastructural analyses. J. Appl. Physiol. 98 (2005) 1777-1783
23. Moreno I.M., Mate A., Repetto G., Vazquez C.M., and Camean A.M. Influence of microcystin-LR on the activity of membrane enzymes in rat intestinal mucosa. J. Physiol. Biochem. 59 4 (2003) 293-299
24. Mortola J.P., and Noworaj A. Two-sidearm tracheal cannula for respiratory airflow measurements in small animals. J. Appl. Physiol. 55 (1983) 250-253
25. Nagase T., Lei M., Robatto F.M., Eidelman D.H., and Ludwig M.S. Tissue viscance during induced constriction in rabbit lung: morphological-physiological correlation. J. Appl. Physiol. 73 (1992) 1900-1907
26. Nakano Y., Shirai M., Mori N., and Nakano M. Neutralization of microcystin shock in mice by tumor necrosis factor alpha antiserum. Appl. Environ. Microbiol. 57 (1991) 327-330
27. Naseen S.M., Hines H.B., and Creasia D.A. Effect of toxins on arachidonic acid metabolism in rat cultured pulmonary alveolar macrophages. Biochem. Inter. 19 (1989) 583-592
28. 2 and cyclooxygenase in renal toxicity induced by microcystin-LR. Toxicon 39 (2001) 721-724
29. Nobre A.C.L., Martins A.M.C., Havt A., Benevides C., Lima A.A.M., Fonteles M.C., and Monteiro H.S.A. Renal effects of supernatant from rat peritoneal macrophages activated by microcystins-LR: role protein mediators. Toxicon 41 (2003) 377-381
30. Pflugmacher S. Possible allelopathic effects of cyanotoxins, with reference to microcystin-LR, in aquatic ecosystems. Environ. Toxicol. 17 (2002) 407-413
31. Picanço M.R., Soares R.M., Cagido V.R., Azevedo S.M.F.O., Rocco P.R.M., and Zin W.A. Toxicity of a cyanobacterial extract containing microcystins to mouse lungs. Braz. J. Med. Biol. Res. 37 8 (2004) 1225-1229
32. Robinson N.A., Matson C.F., and Pace J.G. Association of microcystin-LR and its biotranformation product with a hepatic-cytosolic protein. J. Biochem. Toxicol. 6 (1991) 171-180
33. Rocco P.R.M., and Zin W.A. Pulmonary and extrapulmonary acute respiratory distress syndrome: are they different?. Curr. Opin. Crit. Care 11 (2005) 10-17
34. Runnegar M.T., Kong S., and Berndt N. Protein phosphatase inhibition and in vivo hepatotoxicity of microcystins. Am. J. Physiol. 265 Gastrointst. Liver Physiol., v.28 (1993) g224-g230
35. Sahin A., Tencalla F.G., Dietrich D.R., Mez K., and Naegeli H. Enzymatic analysis of liver samples from rainbow trout for diagnosis of blue-green algae-induced toxicosis. Am. J. Vet. Res. 56 8 (1995) 1110-1115
36. Shenolikar S., and Ingebritsen T.S. Protein (serine and threonine) phosphatases. Methods Enzymol. 107 (1984) 103-129
37. Silveira K.S.O., Boechem N.T., Nascimento S.M., Murakami V.L.B., Barboza A.P.B., Melo P.A., Castro P., Moraes V.L.G., Rocco P.R.M., and Zin W.A. Pulmonary mechanics and lung histology in acute lung injury induced by Bothrops jararaca venom. Respir. Physiol. Neurobiol. 139 (2004) 167-177
38. Similowski T., Levy P., Corbeil C., Albala M., Pariente R., Derenne J.P., Bates J.H.T., Jonson B., and Milic-Emili J. Viscoelastic behavior of lung and chest wall in dogs determined by flow interruption. J. Appl. Physiol. 67 (1989) 2219-2229
39. Slatkin D.N., Stoner R.D., Adams W.H., Kycia J.H., and Siegelman H.W. Atypical pulmonary thrombosis caused by a toxic cyanobacterial peptide. Science 220 (1983) 1383-1385
40. Soares R.M., Yuan M., Servaites J.C., Delgado A., Magalhães V.F., Hilborn E.D., Carmichael W.W., and Azevedo S.M.F.O. Sublethal exposure from microcystins to renal insufficiency patients in Rio de Janeiro, Brazil. Environ. Toxicol. 21 2 (2006) 95-103
41. Turner P.C., Gammie A.J., Hollinrake K., and Codd G.A. Pneumonia associated with cyanobacteria. Br. Med. J. 300 (1990) 1400-1414
42. Wagner J.G., and Roth R.A. Neutrophil migration mechanisms, with an emphasis on the pulmonary vasculature. Pharmacol. Rev. 52 3 (2000) 349-374