The anemia of achylia gastrica revisited

Blood Cells, Molecules, and Diseases

Volumn 39, Issue 2, 2007, Pages 178-183

  Hershko, Chaim ^a,b   Patz, Julian ^a   Ronson, Aharon ^a  

^a HEBREW UNIVERSITY OF JERUSALEM   (Israel)

^b CLALIT HEALTH SERVICES   (Israel)

Author keywords

Achylia gastrica; Atrophic gastritis; Autoimune gastritis; Cobalamin deficiency; Helicobacter pylori; Iron deficiency; Pernicious anemia

Indexed keywords

ACETYLSALICYLIC ACID; HEMOGLOBIN; HYDROGEN POTASSIUM ADENOSINE TRIPHOSPHATASE; IMMUNOGLOBULIN G; IRON; NONSTEROID ANTIINFLAMMATORY AGENT;

ACHLORHYDRIA; AGE DISTRIBUTION; ARTICLE; ATROPHIC GASTRITIS; AUTOIMMUNE DISEASE; CELIAC DISEASE; DISEASE ASSOCIATION; HELICOBACTER INFECTION; HELICOBACTER PYLORI; HUMAN; IRON DEFICIENCY; IRON DEFICIENCY ANEMIA; PERNICIOUS ANEMIA; PREVALENCE; PRIORITY JOURNAL; SEX DIFFERENCE; STOMACH ACID SECRETION; STOMACH ANTRUM; STOMACH MUCOSA; STOMACH PARIETAL CELL; THYROID DISEASE;

ANEMIA, IRON-DEFICIENCY; ANTIBODIES, BACTERIAL; GASTRITIS, ATROPHIC; HELICOBACTER PYLORI; HUMANS; RISK FACTORS;

HELICOBACTER PYLORI;

EID: 34547141180     PISSN: 10799796     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bcmd.2007.03.006     Document Type: Article

References (45)

1. Cook J.D., Skikne B.S., and Baynes R.D. Iron deficiency: the global perspective. Adv. Exp. Med. Biol. 356 (1994) 219-228
2. Rockey D.C., and Cello J.P. Evaluation of the gastrointestinal tract in patients with iron-deficiency anemia. N. Engl. J. Med. 329 (1993) 1691-1695
3. McIntyre A.S., and Long R.G. Prospective survey of investigations in outpatients referred with iron deficiency anaemia. Gut 34 (1993) 1102-1107
4. Bini E.J., Micale P.L., and Weinshel E.H. Evaluation of the gastrointestinal tract in premenopausal women with iron deficiency anemia. Am. J. Med. 105 (1998) 281-286
5. Faber K., and Bloch C.E. Über die pathologischen Veränderungen am digestion-stractus bei der perniciösen anämie und über die sogenannte darm atrophie. Z. Klin. Med. 40 (1900) 98
6. Chanarin I. A history of pernicious anaemia. Br. J. Haematol. 111 (2000) 407-415
7. Faber K. Achylia gastrica mit Anämie. Medizinishe Klinik vol. 5 (1909) 1310-1325
8. Faber K. Anämische Zustände bei der chronischen achylia gastrica. Klin. Wchnschr. 50 (1913) 958
9. Faber K., and Gram H.C. Relations between achylia gastrica and simple and pernicious anemia. Arch. Intern. Med 34 (1924) 658-668
10. Wintrobe M.M., and Beebe R.T. Idiopathic hypochromic anemia. Medicine 12 (1933) 187-243
11. Beutler E., Fairbanks V.F., and Fahey J.L. Clinical Disorders of Iron Metabolism (1963), Grune & Stratton 80-83
12. Davidson W.M.B., and Markson J.L. The gastric mucosa in iron deficiency anaemia. Lancet 269 (1955) 639-643
13. Badenoch J., Evans J.R., and Richards W.C.D. The stomach in hypochromic anemia. Br. J. Haematol. 3 (1957) 175-185
14. Lees F., and Rosenthal F.D. Gastric mucosal lesions before and after treatment in iron-deficiency anemia. Q. J. Med. 27 (1958) 19-26
15. Editorial: Achlorhydria and anaemia. Lancet 2 (1960) 27-28
16. Dagg J.H., Goldberg A., Gibbs W.N., and Anderson J.R. Detection of latent pernicious anaemia in iron-deficiency anaemia. Br. Med. J. 2 (1966) 619-621
17. Dickey W., Kenny B.D., McMillan S.A., Porter K.G., and McConnell J.B. Gastric as well as duodenal biopsies may be useful in the investigation of iron deficiency anaemia. Scand. J. Gastroenterol. 32 (1997) 469-472
18. Annibale B., Capurso G., Chistolini A., et al. Gastrointestinal causes of refractory iron deficiency anemia in patients without gastrointestinal symptoms. Am. J. Med. 111 (2001) 439-445
19. Cook J.D., Brown G.M., and Valberg L.S. The effect of achylia gastrica on iron absorption. J. Clin. Invest. 43 (1964) 1185-1191
20. Schade S.G., Cohen R.J., and Conrad M.E. The effect of hydrochloric acid on iron absorption. N. Engl. J. Med. 279 (1968) 621-624
21. Bezwoda W., Charlton R., Bothwell T., et al. The importance of gastric hydrochloric acid in the absorption of nonheme food iron. J. Lab. Clin. Med. 92 (1978) 108-116
22. Dickey W., and Hughes D. Prevalence of celiac disease and its endoscopic markers among patients having routine upper gastrointestinal endoscopy. Am. J. Gastroenterol. 94 (1999) 2182-2186
23. Choe Y.H., Kwon Y.S., Jung M.K., et al. Helicobacter pylori-associated iron-deficiency anemia in adolescent female athletes. J. Pediatr. 139 (2001) 100-104
24. Annibale B., Marignani M., Monarca B., et al. Reversal of iron deficiency anemia after Helicobacter pylori eradication in patients with asymptomatic gastritis. Ann. Intern. Med. 131 (1999) 668-672
25. Hershko C., Hoffbrand A.V., Keret D., Souroujon M., Maschler I., Monselise Y., and Lahad A. Role of autoimmune gastritis, Helicobacter pylori and celiac disease in refractory or unexplained iron deficiency anemia. Haematologica 90 (2005) 585-595
26. Hershko C., Ronson A., Souroujon M., et al. Variable hematologic presentation of autoimmune gastritis: age-related progression from iron deficiency to cobalamin depletion. Blood 107 (2006) 1673-1679
27. Hershko C., Ianculovich M., and Souroujon M. A hematologist's view of unexplained iron deficiency anemia in males: impact of Helicobacter pylori eradication. Blood Cells Mol. Diseases 38 (2007) 45-53
28. Milman N., Rosenstock S., Andersen L., et al. Serum ferritin, hemoglobin, and Helicobacter pylori infection: a seroepidemiologic survey comprising 2794 Danish adults. Gastroenterology 115 (1998) 268-274
29. Suerbaum S., and Michetti P. Helicobacter pylori infection. N. Engl. J. Med. 347 (2002) 1175-1186
30. Choe Y.H., Kim S.K., Son B.K., et al. Randomized placebo-controlled trial of Helicobacter pylori eradication for iron-deficiency anemia in preadolescent children and adolescents. Helicobacter 4 (1999) 135-139
31. Choe Y.H., Lee J.E., and Kim S.K. Effect of Helicobacter pylori eradication on sideropenic refractory anaemia in adolescent girls with Helicobacter pylori infection. Acta Paediatr. 89 (2000) 154-157
32. Annibale B., Capurso G., Lahner E., et al. Concomitant alterations in intragastric pH and ascorbic acid concentration in patients with Helicobacter pylori gastritis and associated iron deficiency anaemia. Gut 52 (2003) 496-501
33. Stopeck A. Links between Helicobacter pylori infection, cobalamin deficiency, and pernicious anemia. Arch. Intern. Med. 160 (2000) 1229-1230
34. Appelmelk B.J., Simoons-Smit I., Negrini R., et al. Potential role of molecular mimicry between Helicobacter pylori lipopolysaccharide and host Lewis blood group antigens in autoimmunity. Infect. Immun. 64 (1996) 2031-2040
35. Negrini R., Savio A., and Appelmelk B.J. Autoantibodies to gastric mucosa in Helicobacter pylori infection. Helicobacter 1 (1997) S13-S16 (Review)
36. Ma J.Y., Borch K., Sjostrand S.E., et al. Positive correlation between H,K-adenosine triphosphatase autoantibodies and Helicobacter pylori antibodies in patients with pernicious anemia. Scand. J. Gastroenterol. 29 (1994) 961-965
37. Claeys D., Faller G., Appelmelk B.J., et al. The gastric H+,K+-ATPase is a major autoantigen in chronic Helicobacter pylori gastritis with body mucosa atrophy. Gastroenterology 115 (1998) 340-347
38. Negrini R., Savio A., Poiesi C., et al. Antigenic mimicry between Helicobacter pylori and gastric mucosa in the pathogenesis of body atrophic gastritis. Gastroenterology 111 (1996) 655-665
39. Jassel S.V., Ardill J.E., Fillmore D., et al. The rise in circulating gastrin with age is due to increases in gastric autoimmunity and Helicobacter pylori infection. Q. J. Med. 92 (1999) 373-377
40. Appelmelk B.J., Negrini R., Moran A.P., and Kuipers E.J. Molecular mimicry between Helicobacter pylori and the host. Trends Microbiol. 5 (1997) 70-73
41. Rad R., Schmid R.M., and Prinz C. Helicobacter pylori, iron deficiency, and gastric autoimmunity. Blood 107 (2006) 4969-4970
42. Annibale B., Di Giulio E., Caruana P., et al. The long-term effects of cure of Helicobacter pylori infection on patients with atrophic body gastritis. Aliment. Pharmacol. Ther. 16 (2002) 1723-1731
43. Kaptan K., Beyan C., Ural A.U., et al. Helicobacter pylori-is it a novel causative agent in Vitamin B12 deficiency?. Arch. Intern. Med. 160 (2000) 1349-1353
44. Haruma K., Mihara M., Okamoto E., et al. Eradication of Helicobacter pylori increases gastric acidity in patients with atrophic gastritis of the corpus-evaluation of 24-h pH monitoring. Aliment. Pharmacol. Ther. 13 (1999) 155-162
45. McColl K.E.L., Murray L.S., Gillen D., et al. Randomized trial of endoscopy with testing for Helicobacter pylori compared with non-invasive H pylori testing alone in the management of dyspepsia. Br. Med. J. 324 (2002) 999-1002