Concomitant alterations in intragastric pH and ascorbic acid concentration in patients with Helicobacter pylori gastritis and associated iron deficiency anaemia

Gut

Volumn 52, Issue 4, 2003, Pages 496-501

  Annibale, B ^a,b   Capurso, G ^b   Lahner, E ^b   Passi, S ^c   Ricci, R ^c   Maggio, F ^c   Delle Fave, G ^b  

^a POLICLINICO UMBERTO I   (Italy)

^b SAPIENZA UNIVERSITY OF ROME   (Italy)

^c LABORATORIO DI PATOLOGIA VASCOLARE   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIINFECTIVE AGENT; ASCORBIC ACID;

ACHLORHYDRIA; ADULT; AGED; ARTICLE; BACTERIAL VIRULENCE; BLOOD SAMPLING; CLINICAL ARTICLE; CONTROLLED STUDY; DISEASE ASSOCIATION; DISEASE SEVERITY; EPIDEMIOLOGICAL DATA; ERADICATION THERAPY; FEMALE; GASTRITIS; HELICOBACTER PYLORI; HISTOLOGY; HUMAN; HUMAN TISSUE; IRON ABSORPTION; IRON DEFICIENCY ANEMIA; MALE; PRIORITY JOURNAL; STOMACH PH; TREATMENT OUTCOME;

ADULT; AGED; ANEMIA, IRON-DEFICIENCY; ASCORBIC ACID; FEMALE; GASTRIC ACIDITY DETERMINATION; GASTRIC JUICE; GASTRITIS, ATROPHIC; GASTROSCOPY; HELICOBACTER INFECTIONS; HELICOBACTER PYLORI; HUMANS; HYDROGEN-ION CONCENTRATION; MALE; MIDDLE AGED;

EID: 0037379421     PISSN: 00175749     EISSN: None     Source Type: Journal    
DOI: 10.1136/gut.52.4.496     Document Type: Article

References (41)

1. Peach HG, Bath NE, Farish SJ. Helicobacter pylori infection: an added stressor on iron status of women in the community. Med J Aust 1998;169:188-90.
2. Milman N, Rosenstock SJ, Andersen L, et al. Serum ferritin, hemoglobin. and Helicobacter pylori infection: A seroepidemiologic survey comprising 2794 Danish adults. Gastroenterology 1998;115:268-74.
3. Parkinson AJ, Gold BD, Bulkow L, et al. High prevalence of Helicobacter pylori infection in the Alaska native population and association with low serum ferritin levels in young adults. Clin Diagn Lab Immunol 2000;7:885-8.
4. Berg G, Bode G, Blettiner M, et al. Helicobacter pylori infection and serum ferritin: a population based study among 1806 adults in Germany. Am J Gastroenterol 2001;96:1014-19.
5. Annibale B, Marignani M, Monarca B, et al. Reversal of iron deficiency anaemia after Helicobacter pylori eradication in patients with asymptomatic gastritis. Ann Intern Med 1999;131:668-72.
6. Choe YH, Kim SK, Son BK, et al. Randomized placebo-controlled trial of Helicobacter pylori eradication for iron-deficiency anaemia in preadolescent children and adolescents. Helicobacter 1999;4:135-9.
7. Konno M, Muraoka S, Takahashi M, et al. Iron-deficiency anaemia associated with Helicobacter pylori gastritis. J Pediatr Gastroenterol Nutr 2000;31:52-6.
8. Choe YH, Kwon YS, Jung MK, et al. Helicobacter pylori-associated iron-deficiency anaemia in adolescent female athletes. J Pediatr 2001;139:100-4.
9. Annibale B, Capurso G, Chistolini A, et al. Gastrointestinal causes of iron deficiency anaemia in patients without gastrointestinal symptoms. Am J Med 2001;111:439-45.
10. Leontiadis GI, Sharma VK, Howden CW. Non-gastrointestinal tract associations of Helicobacter pylori infection. Arch Intern Med 1999;159:925-40.
11. Bini EJ. Helicobacter pylori and iron deficiency anaemia: guilty as charged? Am J Med 2001;111:495-7.
12. Choe YH, Hwang T-S, Kim HJ, et al. A possible relation of the Helicobacter pylori pfr gene to iron deficiency anaemia? Helicobacter 2001;6:55-9.
13. Capurso G, Lahner E, Marcheggiano A, et al. Involvement of the corporal mucosa and related changes in gastric acid secretion characterize patients with iron deficiency anaemia associated with Helicobacter pylori infection. Aliment Pharmacol Ther 2001;15:1753-62.
14. Annibale B, Negrini R, Caruana P, et al. Two-thirds of atrophic body gastritis patients have evidence of Helicobacter pylori infection. Helicobacter 2001,6:225-33.
15. Kassarjian Z, Russell RM. Hypochlorhydria: a factor in nutrition. Ann Rev Nutr 1989;9:271-85.
16. Dickey W. Iron deficiency, gastric atrophy and Helicobacter pylori. Dig Liver Dis 2002;34:313-15
17. Brittenham GM. Disorders of iron metabolism: Iron deficiency and overload. In: Hoffman R, Benz EJ Jr, Shattil SJ, et al, eds. Haematology, Basic Principles and Practice. 2nd edn. Edinburgh: Churchill Livingstone, 1995:492-523.
18. Condrad ME, Umbreit JN, Moore EG. Iron absorption and transport. Am J Med Sci 1999;318:213-19.
19. Lombard M, Chua E, O'Toole P. Regulation of intestinal non-haem iron absorption. Gut 1997;40:435-9.
20. Rathbone BJ, Johnson AW, Wyatt JI, et al. Ascorbic acid: a factor concentrated in human gastric juice. Clin Sci 1989;76:237-41.
21. Sobala GM, Schorah CJ, Sanderson M, et al. Ascorbic acid in the human stomach. Gastroenterology 1989;97:357-63.
22. Waring AJ, Drake IM, Schorah CJ, et al. Ascorbic acid and total vitamin C concentrations in plasma, gastric juice, and gastrointestinal mucosa: effect of gastritis and oral supplementation. Gut 1996;38:171-6.
23. Zhang ZW, Patchett SE, Perrett D, et al. The relation between gastric vitamin C concentrations, mucosal histology, and CagA seropositivity in the human stomach. Gut 1998;43:322-6.
24. Ruiz B, Carlton Rood J, Fontham ETH, et al. Vitamin C concentration in gastric juice before and after anti-Helicobacter pylori treatment. Am J Gastroenterol 1994;89:533-9.
25. Bordi C, Annibale B, Azzoni C, et al. Endocrine cell growths in atrophic body gastritis. Critical evaluatian of a histolagical classification. J Pathol 1997;182:339-46.
26. Dixon MF, Genta RM, Yardley JH, et al. Classification and grading of gastritis. The updated Sydney System. Am J Surg Pathol 1996;20:1161-18.
27. De Luca C, Filosa A, Grandinetti M, et al. Blood antioxidant status and urinary levels of catecholamine metabolites in beta-thalassemia. Free Radic Res 1999;30:453-62.
28. Bothwell TH, Baynes RD, McFarlane BJ, et al. Nutritional iron requirements and food iron absorption. J Int Med 1989;226:357-65.
29. El-Omar EM, Oien K, El-Nujumi A, et al. Helicobacter pylori infection and chronic gastric acid hyposecretion. Gastroenterology 1997;113:15-24
30. Banerjee S, Hawksby C, Miller S, et al. Effect of Helicobacter pylori and its eradication on gastric juice ascorbic acid. Gut 1994;35:317-22.
31. Sobala GM, Schorah CJ, Shires S, et al. Effect of eradication of Helicobacter pylori on gastric juice ascorbic acid concentrations. Gut 1993;34:1038-41.
32. Skikne BS, Lynch SR, Cook JD. Role of gastric acid in food iron absorption. Gastroenterology 1981;81:1068-71.
33. Stewart CA, Termanini B, Sutliff VE, et al. Iron absorption in patients with Zollinger-Ellison syndrome treated with long-term gastric acid antisecretory therapy. Aliment Pharmacol Ther 1998;12:83-98.
34. Bell N, Karol MD, Sachs G, et al. Duration of effect of lansoprazole on gastric pH and acid secretion in normal male volunteers. Aliment Pharmacol Ther 2001;15:105-13.
35. Mowat C, Carswell A, Wirz A, et al. Omeprazole and dietary nitrate independently affect levels of vitamin C and nitrite in gastric juice. Gastroenterology 1999;116:813-22.
36. Dickey W, Kenny BD, McMillan SA, et al. Gastric as well as duodenal biopsies may be useful in the investigation of iron deficiency anaemia. Scand J Gastroenterol 1997;32:469-72.
37. Marignani M, Delle Fave G, Mecarocci S, et al. High prevalence of atrophic body gastritis in patients with unexplained microcytic and macrocytic anaemia. Am J Gastroenterol 1999;94:766-72.
38. Mooney C, Keenan J, Munster D, et al. Neutrophil activation by Helicobacter pylori. Gut 1991;32:853-7.
39. Woodward M, Tunstall Pedoe H, McColl KEL. Helicobacter pylori infection reduces systemic availability of dietary vitamin C. Eur J Gastroenterol 2001;13:233-7.
40. Annibale B, Aprile MR, D'Ambra G, et al. Cure of Helicobacter pylori infection in atrophic body gastritis patients does not improve mucosal atrophy but reduces hypergastrinemia and its related effects on body ECL-cell hyperplasia. Aliment Pharmacol Ther 2000;14:625-34.
41. Ikkala E, Salmi IU, Siurala M. Gastric mucosa in iron deficiency anaemia. Results of follow-up examinations. Acta Haematol 1970;43:228-31.