Homocysteine, folate and cobalamin levels in hypothyroid women before and after treatment

Endocrine Journal

Volumn 54, Issue 3, 2007, Pages 471-476

  Orzechowska Pawilojc, Anna ^a   Sworczak, Krzysztof ^a   Lewczuk, Anna ^a   Babinska, Anna ^a  

^a MEDICAL UNIVERSITY OF GDANSK   (Poland)

Author keywords

Atherosclerosis; Homocysteine; Hypothyroidism

Indexed keywords

COBALAMIN; CREATININE; FOLIC ACID; HOMOCYSTEINE; LEVOTHYROXINE; LIOTHYRONINE; THYROTROPIN; THYROXINE;

ADULT; ARTICLE; ATHEROGENESIS; CLINICAL ARTICLE; COMPARATIVE STUDY; CONTROLLED STUDY; CREATININE CLEARANCE; ELECTROLYTE BLOOD LEVEL; EUTHYROIDISM; FEMALE; FOLIC ACID BLOOD LEVEL; HUMAN; HYPERHOMOCYSTEINEMIA; HYPOTHYROIDISM; KIDNEY FUNCTION; LIOTHYRONINE BLOOD LEVEL; MULTIVARIATE ANALYSIS; STATISTICAL SIGNIFICANCE; THYROTROPIN BLOOD LEVEL; THYROXINE BLOOD LEVEL; TREATMENT RESPONSE; UNIVARIATE ANALYSIS;

ADULT; CREATINE; FEMALE; FOLIC ACID; HOMOCYSTEINE; HUMANS; HYPOTHYROIDISM; MIDDLE AGED; THYROTROPIN; THYROXINE; VITAMIN B 12;

EID: 34547136470     PISSN: 09188959     EISSN: 13484540     Source Type: Journal    
DOI: 10.1507/endocrj.K06-112     Document Type: Article

References (39)

1. Hak AE, Pols HAP, Visser TJ, Drexhage HA, Hofman A, Witteman JCM (2000) Subclinical hypothyroidism is an independent risk factor for atherosclerosis and myocardial infarction in elderly women: The Rotterdam Study. Ann Intern Med 132: 270-278.
2. Steinberg AD (1968) Myxedema and coronary artery disease - a comparative autopsy study. Ann Intern Med 68: 338-344.
3. Christ-Crain M, Meier C, Guglielmetti M, Huber PR, Riesen W, Staub JJ, Muller B (2003) Elevated C-reactive protein and homocysteine values: cardiovascular risk factors in hypothyroidism? A cross-sectional and a double-blind, placebo-controlled trial. Atherosclerosis 166: 379-386.
4. Tzotzas T, Krassas GE, Konstantinidis T, Bougoulia M (2000) Changes in lipoprotein (a) levels in overt and subclinical hypothyroidism before and during treatment. Thyroid 10: 803-808.
5. Morris MS, Bostom AG, Jacques PF, Selhub J, Rosenberg IH (2001) Hyperhomocysteinemia and hypercholesterolemia associated with hypothyroidism in the third US National Health and Nutrition Examination Survey. Atherosclerosis 155: 195-200.
6. Boushey CJ, Beresford SA, Omenn GS, Motulsky A (1995) A quantitative assessment of plasma homocysteine as a risk factor for vascular disease. Probable benefits of increasing folic acid intakes. JAMA 274: 1049-1057.
7. den Heijer M, Lewington S, Clarke R (2005) Homocysteine, MTHFR and risk of venous thrombosis - a meta analysis of published epidemiological studies. J Thromb Haemost 3: 292-299.
8. Konecky N, Malinow MR, Tunick PA, Freedberg RS, Rosenzweig BP, Katz ES, Hess DL, Upson B, Leung B, Perez J, Kronzon I (1997) Corelation between plasma homocysteine and aortic atherosclerosis. Am Heart J 133: 534-540.
9. 12 and serum total homocysteine levels in confirmed Alzheimer disease. Arch Neurol 55: 1449-1455.
10. Duthie SJ, Whalley LJ, Collins AR, Leaper S, Berger K, Deary IJ (2002) Homocysteine, B vitamin status, and cognitive function in the elderly. Am J Clin Nutr 75: 908-913.
11. Nelen WL, Blom HJ, Steegers EA, den Heijer, Thomas CM, Eskes TK (2000) Homocysteine and folate levels as risk factors for recurrent early pregnancy loss. Obstetrics Gyn 95: 519-524.
12. Clarke R, Collins R, Lewington S, et al. (2002) The Homocysteine Studies Collaboration. Homocysteine and risk of ischemic heart disease and stroke: a meta-analysis JAMA 288: 2015-2022.
13. de Bree A, Verschuren WMM, Kromhout D, Kluijtmans LAJ, Blom HJ (2002) Homocysteine determinants and the evidence to what extent homocysteine determines the risk of coronary heart disease. Pharmacol Rev 54: 599-618.
14. Nallamothu BK, Fendrick AM, Rubenfire M, Saint S, Bandekar RR, Omenn GS (2000) Potential clinical and economic effects on homocysteine lowering. Arch Intern Med 160: 3406-3412.
15. Medina MA, Urdiales JL, Amores-Sanchez MI (2001) Roles of homocysteine in cell metabolism. Eur J Biochem 268: 3871-3882.
16. Finkelstein JD (1998) The metabolism of homocysteine: pathways and regulation. Eur J Pediatr 157: 40-44.
17. Schneede J, Refsum H, Ueland PM (2000) Biological and environmental determinants of plasma homocysteine. Semin Thromb Hemost 26: 263-279.
18. Graham IM, Daly LE, Refsum H, Robinson K, Brattstrom LE, Ueland PM (1997) Plasma homocysteine as a risk factor for vascular disease. The European Concerted Action Project. JAMA 277: 1775-1781.
19. Stanger O, Herrmann W, Pietrzik K, Fowler B, Geisel J, Dierkes J, Weger M (2003) DACH-LIGA Homocystein (German, Austrian and Swiss Homocysteine Society): Consensus paper on the rational clinical use of homocysteine, folic acid and B-vitamins in cardiovascular and thrombotic diseases: guidelines and recommendations. Clin Chem Lab Med 41: 1392-1403.
20. Fiskerstrand T, Refsum H, Kvalheim G, Ueland PM (1993) Homocysteine and other thiols in plasma and urine: automated determination and sample stability. Clin Chem 39: 263-277.
21. Januszewicz W, Kokot F (2004) Choroby uk?adu moczowego, in PZWL (eds.): Interna. Warszawa, vol 2, 619 (In Polish).
22. Catargi B, Parrot-Roulaud F, Cochet C, Ducassou D, Roger P, Tabarin A (1999) Homocysteine, hypothyroidism and effect of thyroid hormone replacement. Thyroid 9: 1163-1166.
23. Nedrebo BG, Ericsson UB, Nygard O, Refsum H, Ueland PM, Aakvaag A, Aanderud S, Lien EA (1998) Plasma total homocysteine levels in hyperthyroid and hypothyroid patients. Metabolism 47: 89-93.
24. Nedrebo BG, Nygard O, Ueland PM, Lien EA (2001) Plasma total homocysteine in hyper- and hypothyroid patients before and during 12 months of treatment. Clin Chem 47: 1738-1741.
25. Lien EA, Nedrebo BG, Varhaug JE, Nygard O, Aakvaagi A, Ueland PM (2000) Plasma total homocysteine levels during short-term iatrogenic hypothyroidism. J Clin Endocrinol Metab 85: 1049-1053.
26. Diekman MJM, van der Put NM, Blom HJ, Tijssen JGP, Wiersinga WM (2001) Determinants of changes in plasma homocysteine in hyperthyroidism and hypothyroidism. Clin Endocrinol 54: 197-204.
27. Morris MS, Jacques PF, Selhub J, Rosenberg H (2000) Total homocysteine and estrogen status indicators in the Third National Health and Nutrition Examination Survey. Am J Epidemiol 152: 140-148.
28. Must A, Jacques PF, Rogers G, Rosenberg I, Selhub I (2003) Serum total homocysteine concentration in children and adolescentes, result from the Third National Health and Nutrition Examination Survey (NHANES III). J Nutr 133: 2643-2649.
29. Tallova J, Tomandl J, Bicikova M, Hill M (1999) Changes of plasma total homocysteine levels during the menstrual cycle. Eur J Clin Invest 29: 1041-1044.
30. Tallova J, Bicikova M, Hill M, Tomandl J, Valentova D (2003) Homocysteine during the menstrual cycle in depressive women. Eur J Clin Invest 33: 268-273.
31. Tonacchera M, Chiovato L, Pinchera A (2002) Clinical assessment and systemic manifestations of hypothyroidism, in J.A.H. Wass and SM. Shalet (eds.): Oxford Textbook of Endocrinology and Diabetes, Oxford University Press, pp. 491-501.
32. 12 levels in hypothyroid and hyperthyroid patients. Arch Intern Med 135: 701-704.
33. 12 levels in rats. J Nutr 118: 1495-1501.
34. Ozmen B, Ozmen D, Parildar Z, Muraf I, Turgan N, Bayindir O (2006) Impact of renal function or folate status on altered plasma homocysteine levels in hypothyroidism. Endocr J 53: 119-124.
35. Nair Parameswaran CP, Gomathy V, Noronha JM (1994) Folate-mediated incorporation of ring-2-carbon of histidine into nucleic acids: influence of thyroid hormone. Metabolism 43: 1575-1578.
36. Rivlin RS, Gamble R, Chung A (1968) Stimulation of hepatic flavin synthesis by thyroid hormone. Excerpta Medica: 33.
37. Hollander JG, Wulkan RW, Mantel MJ, Berghout A (2005) Correlation between severity of thyroid dysfunction and renal function. Clin Endocrinol 62: 423-427.
38. Refsum H, Helland S, Ueland PM (1985) Radioenzymic determination of homocysteine in plasma and urine. Clin Chem 31: 6244-6248.
39. Bostom AG, Culleton BF (1999) Hyperhomocysteinemia in chronic renal disease. J Am Soc Nephrol 10: 891-900.