The 1.8 Å crystal structure of PA2412, an MbtH-like protein from the pyoverdine cluster of Pseudomonas aeruginosa

Journal of Biological Chemistry

Volumn 282, Issue 28, 2007, Pages 20425-20434

  Drake, Eric J ^a,b   Cao, Jin ^c   Qu, Jun ^c   Shah, Manish B ^a   Straubinger, Robert M ^c   Gulick, Andrew M ^a,b  

^a Hautpman Woodward Medical Research Institute   (United States)

^b UNIVERSITY AT BUFFALO   (United States)

^c UNIVERSITY AT BUFFALO   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

MUTANTS; PSEUDOMONAS AERUGINOSA; PYOVERDINE;

BACTERIA; BIOSYNTHESIS; CHROMOPHORES; CRYSTAL STRUCTURE; ENZYME KINETICS; GENE EXPRESSION; MUTAGENESIS;

PROTEINS;

BACTERIAL PROTEIN; MBTH LIKE PROTEIN; ORNITHINE DERIVATIVE; PA2412 PROTEIN; PEPTIDE SYNTHASE; PYOVERDINE; QUINOLINOL DERIVATIVE; UNCLASSIFIED DRUG; ANTIINFECTIVE AGENT; IRON; MYCOBACTINS; OLIGOPEPTIDE; OXAZOLE DERIVATIVE; SIDEROPHORE;

ARTICLE; BACTERIAL GROWTH; CHROMATOPHORE; CRYSTAL STRUCTURE; IRON BINDING CAPACITY; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN PROCESSING; PROTEIN PURIFICATION; PROTEIN SECRETION; PROTEIN STRUCTURE; PROTEIN SYNTHESIS; PSEUDOMONAS AERUGINOSA; THREE DIMENSIONAL IMAGING; ACTIVE TRANSPORT; BINDING SITE; BIOSYNTHESIS; CHEMISTRY; ENZYMOLOGY; GENE DELETION; GENETICS; GROWTH, DEVELOPMENT AND AGING; METABOLISM; MULTIGENE FAMILY; MYCOBACTERIUM TUBERCULOSIS; PHYSIOLOGY; PROTEIN SECONDARY STRUCTURE; PROTEIN TERTIARY STRUCTURE; SEQUENCE HOMOLOGY; X RAY CRYSTALLOGRAPHY;

MYCOBACTERIUM TUBERCULOSIS; PSEUDOMONAS AERUGINOSA;

ANTI-BACTERIAL AGENTS; BACTERIAL PROTEINS; BINDING SITES; BIOLOGICAL TRANSPORT, ACTIVE; CRYSTALLOGRAPHY, X-RAY; GENE DELETION; IRON; MULTIGENE FAMILY; MYCOBACTERIUM TUBERCULOSIS; OLIGOPEPTIDES; OXAZOLES; PEPTIDE SYNTHASES; PROTEIN STRUCTURE, SECONDARY; PROTEIN STRUCTURE, TERTIARY; PSEUDOMONAS AERUGINOSA; SEQUENCE HOMOLOGY; SIDEROPHORES;

EID: 34547116228     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M611833200     Document Type: Article

References (45)

1. Fischbach, M. A., Lin, H., Liu, D. R., and Walsh, C. T. (2006) Nat. Chem. Biol. 2, 132-138
2. Raymond, K. N., Dertz, E. A., and Kim, S. S. (2003) Proc. Natl. Acad. Sci. U. S. A. 100, 3584-3588
3. Visca, P., Imperi, F., and Lamont, I. L. (2007) Trends Microbiol. 15, 22-30
4. Quadri, L. E., Sello, J., Keating, T. A., Weinreb, P. H., and Walsh, C. T. (1998) Chem. Biol. 5, 631-645
5. Crosa, J. H., and Walsh, C. T. (2002) Microbiol. Mol. Biol. Rev. 66, 223-249
6. Renders, N., Verbrugh, H., and Van Belkum, A. (2001) Infect. Genet. Evol. 1, 29-39
7. Meyer, J. M., Neely, A., Stintzi, A., Georges, C., and Holder, I. A. (1996) Infect. Immun. 64, 518-523
8. Fuchs, R., and Budzikiewicz, H. (2001) Curr. Org. Chem. 5, 265-288
9. Kilz, S., Lenz, C., Fuchs, R., and Budzikiewicz, H. (1999) J. Mass Spectrom. 34, 281-290
10. Ochsner, U. A., Wilderman, P. J., Vasil, A. I., and Vasil, M. L. (2002) Mol. Microbiol. 45, 1277-1287
11. Stintzi, A., Johnson, Z., Stonehouse, M., Ochsner, U., Meyer, J. M., Vasil, M. L., and Poole, K. (1999) J. Bacteriol. 181, 4118-4124
12. Somu, R. V., Boshoff, H., Qiao, C., Bennett, E. M., Barry, C. E., III, and Aldrich, C. C. (2006) J. Med. Chem. 49, 31-34
13. Yeats, C., Bentley, S., and Bateman, A. (2003) BMC Microbiol. 3, 3
14. Lin, H., Fischbach, M. A., Liu, D. R., and Walsh, C. T. (2005) J. Am. Chem. Soc. 127, 11075-11084
15. Gehring, A. M., Mori, I., and Walsh, C. T. (1998) Biochemistry 37, 2648-2659
16. Rusnak, F., Sakaitani, M., Drueckhammer, D., Reichert, J., and Walsh, C. T. (1991) Biochemistry 30, 2916-2927
17. Sundlov, J. A., Garringer, J. A., Carney, J. M., Reger, A. S., Drake, E. J., Duax, W. L., and Gulick, A. M. (2006) Acta Crystallogr. D Biol. Crystallogr. 62, 734-740
18. Drake, E. J., Nicolai, D. A., and Gulick, A. M. (2006) Chem. Biol. 13, 409-419
19. Labaer, J., Qiu, Q., Anumanthan, A., Mar, W., Zuo, D., Murthy, T. V., Taycher, H., Halleck, A., Hainsworth, E., Lory, S., and Brizuela, L. (2004) Genome Res. 14, 2190-2200
20. Kapust, R. B., Tozser, J., Fox, J. D., Anderson, D. E., Cherry, S., Copeland, T. D., and Waugh, D. S. (2001) Protein Eng. 14, 993-1000
21. Doubliè, S. (1997) Methods Enzymol. 276, 523-530
22. Rayment, I. (2002) Structure (Camb.) 10, 147-151
23. Gulick, A. M., Horswill, A. R., Thoden, J. B., Escalante-Semerena, J. C., and Rayment, I. (2002) Acta Crystallogr. D Biol. Crystallogr. 58, 306-309
24. Weeks, C. M., Blessing, R. H., Miller, R., Mungee, R., Potter, S. A., Rappleye, J., Smith, G. D., Xu, H., and Furey, W. (2002) Z. Kristallogr. 217, 686-693
25. Terwilliger, T. C. (2001) Acta Crystallogr. D Biol. Crystallogr. 57, 1755-1762
26. Terwilliger, T. C., and Berendzen, J. (1999) Acta Crystallogr. D Biol. Crystallogr. 55, 849-861
27. Murshudov, G. N., Vagin, A. A., and Dodson, E. J. (1997) Acta Crystallogr. D Biol. Crystallogr. 53, 240-255
28. Emsley, P., and Cowtan, K. (2004) Acta Crystallogr. D Biol. Crystallogr. 60, 2126-2132
29. Meyer, J. M., Stintzi, A., De Vos, D., Cornelis, P., Tappe, R., Taraz, K., and Budzikiewicz, H. (1997) Microbiology 143, 35-43
30. Wilderman, P. J., Vasil, A. I., Johnson, Z., Wilson, M. J., Cunliffe, H. E., Lamont, I. L., and Vasil, M. L. (2001) Infect. Immun. 69, 5385-5394
31. Holm, L., and Sander, C. (1995) Trends Biochem. Sci. 20, 478-480
32. Van Roey, P., Meehan, L., Kowalksi, J. C., Belfort, M., and Derbyshire, V. (2002) Nat. Struct. Biol. 9, 806-811
33. Evans, S. P., and Bycroft, M. (1999) J. Mol. Biol. 291, 661-669
34. Stegmann, E., Rausch, C., Stockert, S., Burkert, D., and Wohlleben, W. (2006) FEMS Microbiol. Lett 262, 85-92
35. Lautru, S., Oves-Costales, D., Pernodet, J. L., and Challis, G. L. (2007) Microbiology 153, 1405-1412
36. Wolpert, M., Gust, B., Kammerer, B., and Heide, L. (2007) Microbiology 153, 1413-1423
37. Ferreras, J. A., Ryu, J. S., Di Lello, F., Tan, D. S., and Quadri, L. E. (2005) Nat. Chem. Bio. 1, 29-32
38. Miethke, M., Bisseret, P., Beckering, C. L., Vignard, D., Eustache, J., and Marahiel, M. A. (2006) FEBS J. 273, 409-419
39. Miao, V., Coëffet-LeGal, M.-F., Brian, P., Brost, R., Penn, J., Whiting, A., Martin, S., Ford, R., Parr, I., Bouchard, M., Silva, C. J., Wrigley, S. K., and Baltz, R. H. (2005) Microbiology 151, 1507-1523
40. Magarvey, N. A., Haltli, B., He, M., Greenstein, M., and Hucul, J. A. (2006) Antimicrob. Agents Chemother. 50, 2167-2177
41. Blodgett, J. A., Zhang, J. K., and Metcalf, W. W. (2005) Antimicrob. Agents Chemother. 49, 230-240
42. Chen, H., Hubbard, B. K., O'Connor, S. E., and Walsh, C. T. (2002) Chem. Biol. 9, 103-112
43. Lauer, B., Russwurm, R., and Bormann, C. (2000) Eur. J. Biochem. 267, 1698-1706
44. Galm, U., Schimana, J., Fiedler, H. P., Schmidt, J., Li, S. M., and Heide, L. (2002) Arch. Microbiol. 178, 102-114
45. Edwards, D. J., and Gerwick, W. H. (2004) J. Am. Chem. Soc. 126, 11432-11433