Effects of protein-rich supplementation and nandrolone on bone tissue after a hip fracture

Clinical Nutrition

Volumn 26, Issue 4, 2007, Pages 460-465

  Tengstrand, Birgitta ^a   Cederholm, Tommy ^b   Söderqvist, Anita ^c   Tidermark, Jan ^c  

^a KAROLINSKA UNIVERSITY HOSPITAL   (Sweden)

^b UPPSALA UNIVERSITY   (Sweden)

^c STOCKHOLM SÖDER HOSPITAL   (Sweden)

Author keywords

Bone density; C terminal type I collagen telopeptide; Femoral neck fracture; Nandrolone; Nutrition therapy; Osteocalcin

Indexed keywords

BIOCHEMICAL MARKER; CALCICHEWD3; CALCIUM; CARBOXY TERMINAL TELOPEPTIDE; DECA DURABOL; FORTIMEL; NANDROLONE DECANOATE; OSTEOCALCIN; PROTEIN DERIVATIVE; UNCLASSIFIED DRUG; VITAMIN D;

AGED; ARTICLE; BODY MASS; BONE DENSITY; BONE MINERAL; BONE TISSUE; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DUAL ENERGY X RAY ABSORPTIOMETRY; FEMALE; FEMUR NECK FRACTURE; HIP FRACTURE; HOSPITAL ADMISSION; HUMAN; MAJOR CLINICAL STUDY; OSSIFICATION; OSTEOLYSIS; OSTEOSYNTHESIS; RANDOMIZED CONTROLLED TRIAL; SUPPLEMENTATION;

AGED; AGED, 80 AND OVER; ANABOLIC AGENTS; BIOLOGICAL MARKERS; BODY WEIGHT; BONE DENSITY; DENSITOMETRY, X-RAY; DIETARY PROTEINS; DIETARY SUPPLEMENTS; FEMALE; FRACTURE HEALING; HIP FRACTURES; HUMANS; NANDROLONE; OSTEOCALCIN; OSTEOPOROSIS, POSTMENOPAUSAL; TREATMENT OUTCOME;

EID: 34547095252     PISSN: 02615614     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.clnu.2007.03.007     Document Type: Article

References (19)

1. Åkesson K. Bone and joint diseases around the world. Sweden: a brief update on burden and priority. J Rheumatol Suppl 67 (2003) 38-40
2. Kaptoge S., Dalzell N., Loveridge N., Beck T.J., Khaw K.T., and Reeve J. Effects of gender, anthropometric variables, and aging on the evolution of hip strength in men and women aged over 65. Bone 32 (2003) 561-570
3. Rogers A., Hannon R.A., and Eastell R. Biochemical markers as predictors of rates of bone loss after menopause. J Bone Miner Res 15 (2000) 1398-1404
4. Eyre D.R. Bone biomarkers as tools in osteoporosis management. Spine 22 (1997) 17-24
5. Bonjour J.P., Schürch M.A., and Rizzoli R. Nutritional aspects of hip fractures. Bone 18 (1996) 139-144
6. Avenell A., and Handoll H.H. Nutritional supplementation for hip fracture aftercare in older people. Cochrane Database Syst Rev 2 (2005)
7. Cederholm T., and Hedström M. Nutritional treatment of bone fracture. Curr Opin Clin Nutr Metab Care 8 (2005) 377-381
8. Schürch M.A., Rizzoli R., Slosman D., Vadas L., Vergnaud P., and Bonjour J.P. Protein supplements increase serum insulin-like growth factor-I levels and attenuate proximal femur bone loss in patients with recent hip fracture. A randomized, double-blind, placebo-controlled trial. Ann Intern Med 128 (1998) 801-809
9. Tkatch L., Rapin C.H., Rizzoli R., et al. Benefits of oral protein supplementation in elderly patients with fracture of the proximal femur. J Am Coll Nutr 11 (1992) 519-525
10. Passeri M., Pedrazzoni M., Pioli G., Butturini L., Ruys A.H., and Cortenraad M.G. Effects of nandrolone decanoate on bone mass in established osteoporosis. Maturitas 17 (1993) 211-219
11. Hedström M., Sjöberg K., Brosjö E., Åstrom K., Sjöberg H., and Dalen N. Positive effects of anabolic steroids, vitamin D and calcium on muscle mass, bone mineral density and clinical function after a hip fracture. A randomised study of 63 women. J Bone Joint Surg Br 84 (2002) 497-503
12. Tidermark J., Ponzer S., Carlsson P., et al. Effects of protein-rich supplementation and nandrolone in lean elderly women with femoral neck fractures. Clin Nutr 23 (2004) 587-596
13. Operators Manual, expert-XL software version 1.7 Lunar Corporation Madison, WI; 1998.
14. WHO Study Group. Assessment of fracture risk and its application to screening for postmenopausal osteoporosis. Report of a WHO Study Group. WHO Tech Rep Ser 843 (1994) 1-129
15. Kanis J.A., Melton III L.J., Christiansen C., Johnston C.C., and Khaltaev N. The diagnosis of osteoporosis. J Bone Miner Res 9 (1994) 1137-1141
16. Wasnich R.D., Bagger Y.Z., Hosking D.J., et al. Changes in bone density and turnover after alendronate or estrogen withdrawal. Menopause 11 (2004) 622-630
17. Garnero P., Hausherr E., Chapuy M.C., et al. Markers of bone resorption predict hip fracture in elderly women: the EPIDOS prospective study. J Bone Miner Res 11 (1996) 1531-1538
18. Hedström M., Sjöberg K., Svensson J., Brosjö E., and Dalen N. Changes in biochemical markers of bone metabolism and BMD during the first year after a hip fracture. Acta Orthop Scand 72 (2001) 248-251
19. Shiraki M., Fukuchi M., Kiriyama T., Okamoto S., Ueno T., Sakamoto H., et al. Alfacalcidol reduces accelerated bone turnover in elderly women with osteoporosis. J Bone Miner Metab 22 (2004) 352-359