Pharmacokinetics of Gastrodin in rat plasma and CSF after i.n. and i.v.

International Journal of Pharmaceutics

Volumn 341, Issue 1-2, 2007, Pages 20-25

  Wang, Qiao ^a,b   Chen, Guoshen ^b   Zeng, Su ^a  

^a ZHEJIANG UNIVERSITY   (China)

^b INSTITUTE OF MATERIA MEDICA   (China)

Author keywords

Cerebrospinal fluid; Gastrodin; Nasal administration; Pharmacokinetics; Plasma

Indexed keywords

GASTRODIN; PLANT EXTRACT; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL TISSUE; AREA UNDER THE CURVE; ARTICLE; CEREBROSPINAL FLUID; CONTROLLED STUDY; DRUG TARGETING; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; MALE; NONHUMAN; PRIORITY JOURNAL; RAT; RELIABILITY;

ADMINISTRATION, INTRANASAL; ANIMALS; AREA UNDER CURVE; BENZYL ALCOHOLS; BIOLOGICAL AVAILABILITY; BLOOD-BRAIN BARRIER; CENTRAL NERVOUS SYSTEM AGENTS; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; GLUCOSIDES; INJECTIONS, INTRAVENOUS; MALE; OLFACTORY MUCOSA; RATS; RATS, SPRAGUE-DAWLEY; REPRODUCIBILITY OF RESULTS;

EID: 34447629048     PISSN: 03785173     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ijpharm.2007.03.041     Document Type: Article

References (25)

1. An S.J., Park S.K., Hwang I.K., Choi S.Y., Kim S.K., Kwon O.S., Jung S.J., and Baek N.I. Gastrodin decreases immunoreactivities of gamma-aminobutyric acid shunt emzymes in the hippocampus of seizure-sensitive gerbils. J. Neurosci. Res. 71 (2003) 534-543
2. Cheng G., Hao X.H., Liu G.L., Zou M.J., and Cui F.D. Pharmacokinetics of gastrodin in rats. Chin. Pharm. J. 38 (2003) 127-129
3. Dahlin M., Bergman U., Jansson B., Bjork E., and Brittebo E. Transfer of dopamine in the olfactory pathway following nasal administration in mice. Pharm. Res. 17 (2000) 737-742
4. Dahlin M., and BjÖrk E. Nasal absorption of (S)-UH-301 and its transport into the cerebrospinal fluid of rats. Int. J. Pharm. 195 (2000) 197-205
5. Dahlin M., and BjÖrk E. Nasal administration of a physostigmine analogue (NXX-066) for Alzheimer's disease to rats. Int. J. Pharm. 212 (2001) 264-274
6. Hsieh M.T., Wu C.R., and Chen C.F. Gastrodin and p-hydroxybenzyl alcohol facilitate memory consolidation and retrieval, but not acquisition, on the passive avoidance task in rats. J. Ethnopharmacol. 56 (1997) 45-54
7. Hussain M.A., and Aungst B.J. Intranasal absorption of oxymorphone. J. Pharma. Sci. 86 (1997) 975-976
8. Illum L. Transport of drugs from the nasal cavity to the central nervous system. Eur. J. Pharm. Sci. 11 (2000) 1-18
9. Illum L. Nasal drug delivery-possibilities, problems and solutions. J. Control. Release 87 (2003) 187-198
10. Illum L. Is nose-to-brain transport of drugs in man a reality. J. Pharm. Pharmacol. 56 (2004) 3-17
11. In't Veen J.P.M., van den Berg M.P., Romeijn S.G., Verhoef J.C., and Merkus F.W. Uptake of fluorescein isothiocyanate-labelled dextran into the CSF after intranasal and intravenous administration to rats. Eur. J. Pharm. Biopharm. 61 (2005) 27-31
12. Kao H.D., Traboulsi A., Itoh S., Dittert L., and Hussain A. Enhancement of the systemic and CNS specific delivery of L-dopa by the nasal administration of its water soluble prodrugs. Pharm. Res. 17 (2000) 978-984
13. Kim H.J., Moon K.D., Oh S.Y., Kim S.P., and Lee S.R. Ether fraction of methanol extracts of gastrodia elata, a traditional medicinal herb, protects against kainic acid-induced neuronal damage in the mouse hippocampus. Neurosci. Lett. 314 (2001) 65-68
14. Liu K.X., Han G.Z., Zhang Y.L., Su C.Y., Tang N.Y., and Chen Y.R. Determination of gastrodin in biological specimens and its pharmacokinetics. Acta Pharmacol. Sin. 8 (1987) 409-413
15. Liu Z.H., Hu H.T., Feng G.F., Zhao Z.Y., and Mao N.Y. Protective effects of gastrodin on the cellular model of Alzheimer's disease induced by Abeta25-35. J. Sichuan Univ. (Med. Sci. Edi.). 36 (2005) 537-540
16. Ojemann L.M., Nelson W.L., Shin D.S., Rowe A.O., and Buchanan R.A. Tian ma, an ancient Chinese herb, offers new options for the treatment of epilepsy and other conditions. Epilepsy Behav. 8 (2006) 376-383
17. Pedersen P.S., Braunstein T.H., Jorgensen A., Larsen P.L., Holstein-Rathlou N.H., and Frederiksen O. Stimulation of aquaporin-5 and transepithelial water permeability in human airway epithelium by hyperosmotic stress. Pflugers Arch. 453 (2007) 777-785 (Epub 2006 Oct 17)
18. Sakane T., Akizuki M., Yoshida M., Yamashita S., Nadai T., Hashida M., and Sezaki H. Transport of cephalexin to the cerebrospinal fluid directly from the nasal cavity. J. Pharm. Pharmacol. 43 (1991) 449-451
19. Shi Z., Zhang Q., and Jiang X. Pharmacokinetic behavior in plasma, cerebrospinal fluid and cerebral cortex after intranasal administration of hydrochloride meptazinol. Life Sci. 77 (2005) 2574-2583
20. Van den Berg M.P., Romeijn S.G., Verhoef J.C., and Merkus F.W. Serial cerebrospinal fluid sampling in a rat model to study drug uptake from the nasal cavity. J. Neuosci. Methods 116 (2002) 99-107
21. Van den Berg M.P., Merkus P., Romeijn S.G., Verhoef J.C., and Merkus F.W. Hydroxocobalaminutes uptake into the cerebrospinal fluid after nasal and intravenous delivery in rats and humans. J. Drug. Target. 11 (2003) 325-331
22. Van den Berg M.P., Verhoef J.C., Romeijn S.G., and Merkus F.W. Uptake of estradiol or progesterone into the CSF following intranasal and intravenous delivery in rats. Eur. J. Pharma Biopharm. 58 (2004) 131-135
23. Van den Berg M.P., Merkus P., Romeijn S.G., Verhoef J.C., and Merkus F.W. Uptake of melatonin into the cerebrospinal fluid after nasal and intravenous delivery: studies in rats and comparison with a human study. Pharm Res. 21 (2004) 799-802
24. Wang F., Jiang X., and Lu W. Profiles of methotrexate in blood and CSF following intranasal and intravenous administration to rats. Int. J. Pharm. 263 (2003) 1-7
25. Wang D., Gao Y., and Yun L. Study on brain targeting of raltitrexed following intranasal administration in rats. Cancer Chemother. Pharmacol. 57 (2006) 97-104