The role of angiogenesis in damage and recovery from ischemic stroke

Current Treatment Options in Cardiovascular Medicine

Volumn 9, Issue 3, 2007, Pages 205-212

  Arenillas, Juan F ^a   Sobrino, Tomás ^b   Castillo, José ^b   Dávalos, Antoni ^b  

^a Department of Neurosciences   (Spain)

^b NONE

Author keywords

[No Author keywords available]

Indexed keywords

2,4 THIAZOLIDINEDIONE DERIVATIVE; ATORVASTATIN; GLITAZONE DERIVATIVE; GROWTH FACTOR; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE INHIBITOR; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA AGONIST; RECOMBINANT PROTEIN; SCATTER FACTOR; SIMVASTATIN; VASCULOTROPIN;

ANGIOGENESIS; BRAIN ISCHEMIA; CEREBROVASCULAR ACCIDENT; CHRONIC DISEASE; CLINICAL TRIAL; CONGESTIVE HEART FAILURE; DIET; DISEASE MODEL; DRUG BIOAVAILABILITY; DRUG EFFICACY; DRUG MECHANISM; DRUG MEGADOSE; DRUG SAFETY; ENDOTHELIUM CELL; GENE THERAPY; GENE TRANSFER; HEART MUSCLE ISCHEMIA; HOSPITALIZATION; HUMAN; LIFESTYLE; LIVER TOXICITY; MORBIDITY; MORTALITY; MUSCLE DISEASE; NONHUMAN; PHYSICAL ACTIVITY; REVIEW; SIDE EFFECT; STEM CELL; TISSUE REGENERATION; TISSUE REPAIR; WEIGHT GAIN;

EID: 34447580186     PISSN: 10928464     EISSN: None     Source Type: Journal    
DOI: 10.1007/s11936-007-0014-5     Document Type: Review

References (50)

1. Murray CJ, Lopez AD: Alternative projections of mortality and disability by cause 1990-2020: Global Burden of Disease Study. Lancet 1997, 349:1498-1504.
2. Hurtado O, Pradillo JM, Alonso-Escolano D, et al.: Neurorepair versus neuroprotection in stroke. Cerebrovasc Dis 2006, 21(suppl 2):54-63.
3. Liu XS, Zhang ZG, Zhang RL, et al.: Stroke induces gene profile changes associated with neurogenesis and angiogenesis in adult subventricular zone progenitor cells. J Cereb Blood Flow Metab 2006, Jul 12; [Epub ahead of print].
4. Hayashi T, Noshita N, Sugawara T, Chan PH: Temporal profile of angiogenesis and expression of related genes in the brain after ischemia. J Cereb Blood Flow Metab 2003, 23:166-180.
5. Krupinski J, Kaluza J, Kumar P, et al.: Role of angiogenesis in patients with cerebral ischemic stroke. Stroke 1994, 25:1794-1798.
6. Manoonkitiwongsa PS, Jackson-Friedman C, McMillan PJ, et al.: Angiogenesis after stroke is correlated with increased numbers of macrophages: the clean-up hypothesis. J Cereb Blood Flow Metab 2001, 21:1223-1231.
7. Arenillas JF, Alvarez-Sabin J, Montaner J, et al.: Angiogenesis in symptomatic intracranial atherosclerosis: predominance of the inhibitor endostatin is related to a greater extent and risk of recurrence. Stroke 2005, 36:92-97.
8. Asahara T, Masuda H, Takahashi T, et al.: Bone marrow origin of endothelial progenitor cells responsible for post-natal vasculogenesis in physiological and pathological neovascularization. Circ Res 1999, 85:221-228.
9. Hill JM, Zalos G, Halcox JP, et al.: Circulating endothelial progenitor cells, vascular function, and cardiovascular risk. N Engl J Med 2003, 348:593-600.
10. Zhang ZG, Zhang L, Jiang Q, Chopp M: Bone marrow-derived endothelial progenitor cells participate in cerebral neovascularization after focal cerebral ischemia in the adult mouse. Circ Res 2002, 90:284-288.
11. Ghani U, Shuaib A, Salam A, et al.: Endothelial progenitor cells during cerebrovascular disease. Stroke 2005, 36:151-153.
12. Sobrino T, Arenillas JF, Brea D, et al.: Relationship between endothelial progenitor cells (EPCs) and outcome in ischemic stroke [abstract]. Cerebrovasc Dis 2006, 21(suppl 4):98.
13. Hacke W, Kaste M, Bogousslavsky J, et al.: European Stroke Initiative Recommendations for Stroke Management-update 2003. Cerebrovasc Dis 2003, 16:311-337.
14. Stroke Unit Trialists' Collaboration: Organised inpatient (stroke unit) care for stroke. Cochrane Database Syst Rev 2002, 1:CD000197.
15. Endres M, Gertz K, Lindauer U, et al.: Mechanisms of stroke protection by physical activity. Ann Neurol 2003, 54:582-590.
16. Laufs U, Werner N, Link A, et al.: Physical training increases endothelial progenitor cells, inhibits neointima formation, and enhances angiogenesis. Circulation 2004, 109:220-226.
17. Gertz K, Priller J, Kronenberg G, et al.: Physical activity improves long-term stroke outcome via endothelial nitric oxide synthase-dependent augmentation of neovascularization and cerebral blood flow. Circ Res 2006, 99:1132-1140.
18. Deplanque D, Masse I, Lefebvre C, et al.: Prior TIA, lipid-lowering drug use, and physical activity decrease ischemic stroke severity. Neurology 2006, 67:1403-1410.
19. Madeddu P: Therapeutic angiogenesis and vasculogenesis for tissue regeneration. Exp Physiol 2005, 90:315-326.
20. Endres M: Statins and stroke. J Cereb Blood Flow Metab 2005, 25:1093-1110.
21. Chen J, Zhang ZG, Li Y, et al.: Statins induce angiogenesis, neurogenesis, and synaptogenesis after stroke. Ann Neurol 2003, 53:743-751.
22. Zhang R, Wang L, Zhang L, et al.: Nitric oxide enhances angiogenesis via the synthesis of vascular endothelial growth factor and cGMP after stroke in the rat. Circ Res 2003, 92:308-313.
23. Chen J, Zhang C, Jiang H, et al.: Atorvastatin induction of VEGF and BDNF promotes brain plasticity after stroke in mice. J Cereb Blood Flow Metab 2005, 25:281-290.
24. Amarenco P, Bogousslavsky J, Callahan A 3rd, et al.: High-dose atorvastatin after stroke or transient ischemic attack. N Engl J Med 2006, 355:549-559.
25. Montaner J: Treatment with statins in the acute phase of ischemic stroke. Expert Rev Neurother 2005, 5:211-221.
26. Pistrosch F, Herbrig K, Oelschlaegel U, et al.: PPARgamma-agonist rosiglitazone increases number and migratory activity of cultured endothelial progenitor cells. Atherosclerosis 2005, 183:163-167.
27. Gensch C, Clever YP, Werner C, et al.: The PPAR-gamma agonist pioglitazone increases neoangiogcnesis and prevents apoptosis of endothelial progenitor cells. Atherosclerosis 2006, Jul 27; [Epub ahead of print].
28. Yki-Järvinen H: The PROactive study: some answers, many questions. Lancet 2005, 366:1241-1242.
29. Henry TD, Annex BH, McKendall GR, et al.: The VIVA trial: Vascular endothelial growth factor in Ischemia for Vascular Angiogenesis. Circulation 2003, 107:1359-1365.
30. Simons M, Annex BH, Laham RJ, et al.: Pharmacological treatment of coronary artery disease with recombinant fibroblast growth factor-2. Double-blind, randomised, controlled clinical trial. Circulation 2002, 105:788-793.
31. Lederman RJ, Mendelsohn FO, Anderson RD, et al.: Therapeutic angiogenesis with recombinant fibroblast growth factor-2 for intermittent claudication (the TRAFFIC study): a randomised trial. Lancet 2002, 359:2053-2058.
32. Grines CL, Emanueli C, Desortes E, et al.: Angiogenic Gene Therapy (AGENT) trial in patients with stable angina pectoris. Circulation 2002, 105:1291-1297.
33. Makinen K, Manninen H, Hedman M, et al.: Increased vascularity detected by digital subtraction angiography after VEGF gene transfer to human lower limb artery: a randomised, placebo-controlled, double blinded phase II study. Mol Ther. 2002; 6:127-133.
34. Wang Y, Galvan V, Gorostiza O, et al.: Vascular endothelial growth factor improves recovery of sensorimotor and cognitive deficits after focal cerebral ischemnia in the rat. Brain Res 2006, 1115:186-193.
35. Bellomo M, Adamo EB, Deodato B, et al.: Enhancement of expression of vascular endothelial growth factor after adeno-associated virus gene transfer is associated with improvement of brain ischemia injury in the gerbil. Pharmacol Res 2003, 48:309-317.
36. Zhang ZG, Zhang L, Tsang W, et al.: Correlation of VEGF and angiopoietin expression with disruption of blood-brain barrier and angiogenesis after focal cerebral ischemia. J Cereb Blood Flow Metab 2002, 22:379-392.
37. Abumiya T, Yokota C, Kuge Y, Minematsu K: Aggravation of hemorrhagic transformation by early intra-arterial infusion of low-dose vascular endothelial growth factor after transient focal cerebral ischemia in rats. Brain Res 2005, 1049:95-103.
38. Manoonkitiwongsa PS, Schultz RL, Whitter EF, Lyden PD: Contraindications of VEGF-based therapeutic angiogenesis: effects on macrophage density and histology of normal and ischemic brains. Vascul Pharmacol 2006, 44:316-325.
39. Weis SM, Cheresh DA: Pathophysiological consequences of VEGF-induced vascular permeability. Nature 2005, 437:497-504.
40. Kimura R, Nakase H, Tamaki R, Sakaki T: Vascular endothelial growth factor antagonist reduces brain edema formation and venous infarction. Stroke 2005, 36:1259-1263.
41. Kaya D, Gursoy-Ozdemir Y, Yemisci M, et al.: VEGF protects brain against focal ischemia without increasing blood-brain permeability when administered intracerebroventricularly. J Cereb Blood Flow Metab 2005, 25:1111-1118.
42. Shimamura M, Sato N, Oshima K, et al.: Novel therapeutic strategy to treat brain ischemia: overexpression of hepatocyte growth factor gene reduced ischemic injury without cerebral edema in rat model. Circulation 2004, 109:424-431.
43. Shyu WC, Lin SZ, Chiang MF, et al.: Intracerebral peripheral blood stem cell (CD34+) implantation induces neuroplasticity by enhancing betal integrin-mediated angiogenesis in chronic stroke rats. J Neurosci 2006, 26:3444-3453.
44. Chen J, Zhang ZG, Li Y, et al.: Intravenous administration of human bone marrow stromal cells induces angiogenesis in the ischemic boundary zone after stroke in rats. Circ Res 2003, 92:692-699.
45. Tse HF, Thambar S, Kwong YL, et al.: Safety of catheter-based intramyocardial autologous bone marrow cells implantation for therapeutic angiogenesis. Am J Cardiol 2006, 98:60-62.
46. Stamm C, Westphal B, Kleine HD, et al.: Autologous bone-marrow stem-cell transplantation for myocardial regeneration. Lancet 2003, 361:45-46.
47. Tateishi-Yuyama E, Matsubara H, Murohara T, et al.: Therapeutic angiogenesis for patients with limb ischaemia by autologous transplantation of bone-marrow cells: a pilot study and a randomised controlled trial. Lancet 2002, 360:427-435.
48. Shyu WC, Lin SZ, Yang HI, et al.: Functional recovery of stroke rats induced by granulocyte colony-stimulating factor-stimulated stem cells. Circulation 2004, 110:1847-1854.
49. Tepper OM, Galiano RD, Capla JM, et al.: Human endothelial progenitor cells from type II diabetics exhibit impaired proliferation, adhesion, and incorporation into vascular structures. Circulation 2002, 106:2781-2786.
50. Verma S, Kuliszewski MA, Li SH, et al.: Greactive protein attenuates endothelial progenitor cell survival, differentiation, and function: further evidence of a mechanistic link between C-reactive protein and cardiovascular disease. Circulation 2004, 109:2058-2067.