The anxiolytic effects of midazolam during anticipation to pain revealed using fMRI

Magnetic Resonance Imaging

Volumn 25, Issue 6, 2007, Pages 801-810

  Wise, Richard G ^a   Lujan, Brandon J ^a   Schweinhardt, Petra ^b   Peskett, Guy D ^b   Rogers, Richard ^a   Tracey, Irene ^a,b  

^a UNIVERSITY OF OXFORD   (United Kingdom)

^b UNIVERSITY OF OXFORD   (United Kingdom)

Author keywords

Anxiety; Anxiolysis; fMRI; Midazolam; Neuroimaging; Pain

Indexed keywords

MIDAZOLAM; SODIUM CHLORIDE;

ADULT; ANXIETY; ARTICLE; BRAIN REGION; BRAIN STEM; CEREBELLUM; CHRONIC PAIN; CINGULATE GYRUS; COHORT ANALYSIS; FUNCTIONAL MAGNETIC RESONANCE IMAGING; HUMAN; HUMAN EXPERIMENT; INSULA; MALE; MOTOR CORTEX; NEUROIMAGING; NEUROMODULATION; NOCICEPTIVE STIMULATION; NORMAL HUMAN; PAIN; PREFRONTAL CORTEX; PRIORITY JOURNAL; RIGHT HANDEDNESS; THALAMUS; THERMAL STIMULATION; TRANQUILIZING ACTIVITY;

ANTI-ANXIETY AGENTS; BEHAVIOR; BRAIN; BRAIN MAPPING; COHORT STUDIES; COLOR; DIAZEPAM; HUMANS; LIGHT; MAGNETIC RESONANCE IMAGING; MALE; MIDAZOLAM; PAIN; PAIN MEASUREMENT; TOMOGRAPHY, EMISSION-COMPUTED, SINGLE-PHOTON;

EID: 34447576431     PISSN: 0730725X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.mri.2007.03.016     Document Type: Article

References (37)

1. Crombez G., Vlaeyen J.W., Heuts P.H., and Lysens R. Pain-related fear is more disabling than pain itself: evidence on the role of pain-related fear in chronic back pain disability. Pain 80 1-2 (1999) 329-339
2. Ploghaus A., Narain C., Beckmann C.F., Clare S., Bantick S., Wise R., et al. Exacerbation of pain by anxiety is associated with activity in a hippocampal network. J Neurosci 21 24 (2001) 9896-9903
3. Peyron R., Laurent B., and Garcia-Larrea L. Functional imaging of brain responses to pain. A review and meta-analysis (2000). Neurophysiol Clin 30 5 (2000) 263-288
4. Rainville P. Brain mechanisms of pain affect and pain modulation. Curr Opin Neurobiol 12 2 (2002) 195-204
5. Porro C.A. Functional imaging and pain: behavior, perception, and modulation. Neuroscientist 9 5 (2003) 354-369
6. Tracey I. Nociception in the human brain. Curr Opin Neurobiol 15 4 (2005) 478-487
7. Ploghaus A., Tracey I., Gati J.S., Clare S., Menon R.S., Matthews P.M., et al. Dissociating pain from its anticipation in the human brain. Science 284 5422 (1999) 1979-1981
8. Ploghaus A., Becerra L., Borras C., and Borsook D. Neural circuitry underlying pain modulation: expectation, hypnosis, placebo. Trends Cogn Sci 7 5 (2003) 197-200
9. Buchel C., Morris J., Dolan R.J., and Friston K.J. Brain systems mediating aversive conditioning: an event-related fMRI study. Neuron 20 5 (1998) 947-957
10. Chua P., Krams M., Toni I., Passingham R., and Dolan R. A functional anatomy of anticipatory anxiety. Neuroimage 9 6 Pt 1 (1999) 563-571
11. Porro C.A., Baraldi P., Pagnoni G., Serafini M., Facchin P., Maieron M., et al. Does anticipation of pain affect cortical nociceptive systems?. J Neurosci 22 8 (2002) 3206-3214
12. Hsieh J.C., Stone-Elander S., and Ingvar M. Anticipatory coping of pain expressed in the human anterior cingulate cortex: a positron emission tomography study. Neurosci Lett 262 1 (1999) 61-64
13. Low K., Crestani F., Keist R., Benke D., Brunig I., Benson J.A., et al. Molecular and neuronal substrate for the selective attenuation of anxiety. Science 290 5489 (2000) 131-134
14. Malizia A.L. Receptor binding and drug modulation in anxiety. Eur Neuropsychopharmacol 12 6 (2002) 567-574
15. Di Piero V., Ferracuti S., Sabatini U., Tombari D., Di Legge S., Pantano P., et al. Diazepam effects on the cerebral responses to tonic pain: a SPET study. Psychopharmacology (Berl) 158 3 (2001) 252-258
16. Greenblatt D.J., Harmatz J.S., Engelhardt N., and Shader R.I. Pharmacokinetic determinants of dynamic differences among three benzodiazepine hypnotics. Flurazepam, temazepam, and triazolam. Arch Gen Psychiatry 46 4 (1989) 326-332
17. Smith S.M., Jenkinson M., Woolrich M.W., Beckmann C.F., Behrens T.E., Johansen-Berg H., et al. Advances in functional and structural MR image analysis and implementation as FSL. Neuroimage 23 Suppl 1 (2004) S208-S219
18. Jenkinson M., Bannister P., Brady M., and Smith S. Improved optimization for the robust and accurate linear registration and motion correction of brain images. Neuroimage 17 2 (2002) 825-841
19. Woolrich M.W., Ripley B.D., Brady M., and Smith S.M. Temporal autocorrelation in univariate linear modeling of FMRI data. Neuroimage 14 6 (2001) 1370-1386
20. Jenkinson M., and Smith S. A global optimisation method for robust affine registration of brain images. Med Image Anal 5 2 (2001) 143-156
21. Forman S.D., Cohen J.D., Fitzgerald M., Eddy W.F., Mintun M.A., and Noll D.C. Improved assessment of significant activation in functional magnetic resonance imaging (fMRI): use of a cluster-size threshold. Magn Reson Med 33 5 (1995) 636-647
22. Friston K.J., Worsley K.J., Frackowiak R.S., Maziotta J.C., and Evans A.C. Assessing the significance of focal activations using their spatial extent. Hum Brain Mapp 1 (1994) 214-220
23. Worsley K.J., Evans A.C., Marrett S., and Neelin P. A three-dimensional statistical analysis for CBF activation studies in human brain. J Cereb Blood Flow Metab 12 6 (1992) 900-918
24. Devinsky O., Morrell M.J., and Vogt B.A. Contributions of anterior cingulate cortex to behaviour. Brain 118 Pt 1 (1995) 279-306
25. Jones A.K., Brown W.D., Friston K.J., Qi L.Y., and Frackowiak R.S. Cortical and subcortical localization of response to pain in man using positron emission tomography. Proc R Soc Lond B Biol Sci 244 1309 (1991) 39-44
26. Talbot J.D., Marrett S., Evans A.C., Meyer E., Bushnell M.C., and Duncan G.H. Multiple representations of pain in human cerebral cortex. Science 251 4999 (1991) 1355-1358
27. Davis K.D., Taylor S.J., Crawley A.P., Wood M.L., and Mikulis D.J. Functional MRI of pain- and attention-related activations in the human cingulate cortex. J Neurophysiol 77 6 (1997) 3370-3380
28. Peyron R., Garcia-Larrea L., Gregoire M.C., Costes N., Convers P., Lavenne F., Mauguiere F., et al. Haemodynamic brain responses to acute pain in humans: sensory and attentional networks. Brain 122 Pt 9 (1999) 1765-1780
29. Craig A.D., Reiman E.M., Evans A., and Bushnell M.C. Functional imaging of an illusion of pain. Nature 384 6606 (1996) 258-260
30. Critchley H.D., Mathias C.J., and Dolan R.J. Neural activity in the human brain relating to uncertainty and arousal during anticipation. Neuron 29 2 (2001) 537-545
31. Johansen J.P., and Fields H.L. Glutamatergic activation of anterior cingulate cortex produces an aversive teaching signal. Nat Neurosci 7 4 (2004) 398-403
32. Petrovic P., Kalso E., Petersson K.M., and Ingvar M. Placebo and opioid analgesia - imaging a shared neuronal network. Science 295 5560 (2002) 1737-1740
33. Tracey I., Ploghaus A., Gati J.S., Clare S., Smith S., Menon R.S., et al. Imaging attentional modulation of pain in the periaqueductal gray in humans. J Neurosci 22 7 (2002) 2748-2752
34. Craig A.D. Interoception: the sense of the physiological condition of the body. Curr Opin Neurobiol 13 4 (2003) 500-505
35. Critchley H.D., Wiens S., Rotshtein P., Ohman A., and Dolan R.J. Neural systems supporting interoceptive awareness. Nat Neurosci 7 2 (2004) 189-195
36. Sawamoto N., Honda M., Okada T., Hanakawa T., Kanda M., Fukuyama H., et al. Expectation of pain enhances responses to nonpainful somatosensory stimulation in the anterior cingulate cortex and parietal operculum/posterior insula: an event-related functional magnetic resonance imaging study. J Neurosci 20 19 (2000) 7438-7445
37. Pizzagalli D.A., Greischar L.L., and Davidson R.J. Spatio-temporal dynamics of brain mechanisms in aversive classical conditioning: high-density event-related potential and brain electrical tomography analyses. Neuropsychologia 41 2 (2003) 184-194