Growth hormone-releasing peptide-2 reduces inward rectifying K+ currents via a PKA-cAMP-mediated signalling pathway in ovine somatoropes

Journal of Physiology

Volumn 545, Issue 2, 2002, Pages 421-433

  Xu, Ruwei ^a   Zhao, Yufeng ^a   Chen, Chen ^a  

^a HUDSON INSTITUTE OF MEDICAL RESEARCH   (Australia)

Author keywords

[No Author keywords available]

Indexed keywords

CHELERYTHRINE; CYCLIC AMP; CYCLIC AMP DEPENDENT PROTEIN KINASE; CYCLIC AMP DEPENDENT PROTEIN KINASE INHIBITOR; GROWTH HORMONE ANTIBODY; INWARDLY RECTIFYING POTASSIUM CHANNEL; N [2 (4 BROMOCINNAMYLAMINO)ETHYL] 5 ISOQUINOLINESULFONAMIDE; NYSTATIN; PEPTIDE; POTASSIUM ION; PRALMORELIN; GROWTH HORMONE; PROTEIN KINASE C;

ADOLESCENT; ANIMAL CELL; ANIMAL TISSUE; ARTICLE; CELL CULTURE; CELL LINE; CONCENTRATION (PARAMETERS); CONTROLLED STUDY; DEPOLARIZATION; GROWTH HORMONE RELEASE; HYPERPOLARIZATION; HYPOPHYSIS CELL; MEMBRANE STEADY POTENTIAL; NONHUMAN; PATCH CLAMP; POTASSIUM CURRENT; POTASSIUM TRANSPORT; PRIORITY JOURNAL; SHEEP; SIGNAL TRANSDUCTION; STAINING; ENZYME ACTIVITY; ENZYME ASSAY; ENZYME SPECIFICITY; MOLECULAR DYNAMICS; PROTEIN DETERMINATION; PROTEIN FUNCTION; PROTEIN LOCALIZATION; PROTEIN SECRETION; RAT;

ANIMALS; BARIUM COMPOUNDS; CELL SEPARATION; CELLS, CULTURED; CESIUM; CHLORIDES; CYCLIC AMP; CYCLIC AMP-DEPENDENT PROTEIN KINASES; ELECTROPHYSIOLOGY; GROWTH HORMONE; IMMUNOHISTOCHEMISTRY; MEMBRANE POTENTIALS; OLIGOPEPTIDES; PATCH-CLAMP TECHNIQUES; PITUITARY GLAND; POTASSIUM; POTASSIUM CHANNELS, INWARDLY RECTIFYING; RATS; SHEEP; SIGNAL TRANSDUCTION;

EID: 0036905839     PISSN: 00223751     EISSN: None     Source Type: Journal    
DOI: 10.1113/jphysiol.2002.030916     Document Type: Article

References (54)

1. ADAMS, E. F., LEI, T., BUCHFELDER, M., BOWERS, C. Y. & FAHLBUSCH, R. (1996). Protein kinase C-dependent growth hormone releasing peptides stimulate cyclic adenosine 3′,5′-monophosphate production by human pituitary somatotropinomas expressing gsp oncogenes: evidence for cross talk between transduction pathways. Molecular Endocrinology 10, 432-438.
2. + current with a cell-cycle dependence governs the resting potential of mammalian neuroblastoma cells. Journal of Physiology 489, 455-471.
3. + current in patch-perforated GH3 anterior pituitary cells. Pflügers Archiv 422, 31-39.
4. + channel gating by activation of a G protein-coupled receptor and protein kinase C. Journal of Physiology 511, 333-346.
5. + current in resting potential and thyrotropin-releasing-hormone-induced changes in cell excitability of GH3 rat anterior pituitary cells. Pflügers Archiv 426, 221-230.
6. + current and its modulation by thyrotrophin-releasing hormone in giant clonal rat anterior pituitary cells. Journal of Physiology 510, 63-70.
7. BAUER, C. K., DAVISON, I., KUBASOV, I., SCHWARZ, J. R. & MASON, W. T. (1994). Different G proteins are involved in the biphasic response of clonal rat pituitary cells to thyrotropin-releasing hormone. Pflügers Archiv 428, 17-25.
8. + current in clonal rat pituitary cells and its modulation by thyrotropin-releasing hormone. Journal of Physiology 429, 169-189.
9. + current in prolactin secretion from rat lactotrophs. Molecular and Cellular Endocrinology 148, 37-45.
10. BOWERS, C. Y. (1998). Growth hormone-releasing peptide (GHRP). Cellular and Molecular Life Sciences 54, 1316-1329.
11. 2+ oscillations and have distinct roles in prolactin release in GH3 cells. Journal of Biological Chemistry 274, 7508-7515.
12. + currents in ovine pituitary somatotrophs. Clinical and Experimental Pharmacology and Physiology 24, 639-645.
13. CHEN, C. (2000). Growth hormone secretagogue actions on the pituitary gland: multiple receptors for multiple ligands? Clinical and Experimental Pharmacology and Physiology 27, 323-329.
14. 2+ permeability in cultured ovine somatotrophs. Journal of Neuroendocrinology 7, 179-186.
15. CHEN, C., HEYWARD, P., ZHANG, J.,WU, D. & CLARKE, I. J. (1994a). Voltage-dependent potassium currents in ovine somatotrophs and their function in growth hormone secretion. Neuroendocrinology 59, 1-9.
16. CHEN, C., VINCENT, J. D. & CLARKE, I. J. (1994b). Ion channels and signal transduction pathways in the regulation of growth hormone secretion. Trends in Endocrinology and Metabolism 5, 227-233.
17. CHEN, C., WU, D. & CLARKE, I. J. (1996). Signal transduction systems employed by synthetic GH-releasing peptides in somatotrophs. Journal of Endocrinology 148, 381-386.
18. GREGERSON, K. A., FLAGG, T. P., O'NEILL, T. J., ANDERSON, M., LAURING, O., HOREL, J. S. & WELLING, P. A. (2001). Identification of G protein-coupled, inward rectifier potassium channel gene products from the rat anterior pituitary gland. Endocrinology 142, 2820-2832.
19. HAGIWARA, S. & TAKAHASHI, K. (1974). The anomalous rectification and cation selectivity of the membrane of a starfish egg cell. Journal of Membrane Biology 18, 61-80.
20. + channels expressed in Xenopus oocytes. Journal of Physiology 495, 681-688.
21. HOWARD, A. D., FEIGHNER, S. D., CULLY, D. F., ARENA, J. P., LIBERATOR, P. A., ROSENBLUM, C. I., HAMELIN, M., HRENIUK, D. L., PALYHA, O. C., ANDERSON, J., PARESS, P. S., DIAZ, C., CHOU, M., LIU, K. K., MCKEE, K. K., PONG, S. S., CHAUNG, L. Y., ELBRECHT, A., DASHKENICZ, M., HEAVENS, R., RIGBY, M., SIRINATHSINGHJI, D. J., DEAN, D. C., MELILLO, D. G., PATCHETT, A. A., NARGUND, R., GRIFFIN, P. R., DEMARTINO, J. A., GUPTA, S. K., SCHAEFFER, J. M., SMITH, R. G. & VAN DER PLOEG, L. H. (1996). A receptor in pituitary and hypothalamus that functions in growth hormone release. Science 273, 974-977.
22. ISOMOTO, S., KONDO, C. & KURACHI, Y. (1997). Inwardly rectifying potassium channels: their molecular heterogeneity and function. Japanese Journal of Physiology 47, 11-39.
23. JIANG, Z. G., SI, J. Q., LASAREV, M. R. & NUTTALL, A. L. (2001). Two resting potential levels regulated by the inward-rectifier potassium channel in the guinea-pig spiral modiolar artery. Journal of Physiology 537, 829-842.
24. + current is inhibited by beta(1)-adrenoreceptor activation, via cAMP/protein kinase A-dependent pathways. Cardiovascular Research 53, 355-362.
25. + current in the primary cultured rat somatotroph. Endocrinology 138, 5096-5100.
26. + concentration of rat pituitary cells in primary culture. Journal of Neuroendocrinology 11, 795-800.
27. KOJIMA, M., HOSODA, H., DATE, Y., NAKAZATO, M., MATSUO, H. & KANGAWA, K. (1999). Ghrelin is a growth-hormone-releasing acylated peptide from stomach. Nature 402, 656-660.
28. KUBO, Y., BALDWIN, T. J., JAN, Y. N. & JAN, L. Y. (1993). Primary structure and functional expression of a mouse inward rectifier potassium channel. Nature 362, 127-133.
29. KURYSHEV, Y. A., HAAK, L., CHILDS, G. V. & RITCHIE, A. K. (1997). Corticotropin releasing hormone inhibits an inwardly rectifying potassium current in rat corticotropes. Journal of Physiology 502, 265-279.
30. LIGHT, P. E., BLADEN, C., WINKFEIN, R. J., WALSH, M. P. & FRENCH, R. J. (2000). Molecular basis of protein kinase C-induced activation of ATP-sensitive potassium channels. Proceedings of the National Academy of Sciences of the USA 97, 9058-9063.
31. LIOU, H. H., ZHOU, S. S. & HUANG, C. L. (1999). Regulation of ROMK1 channel by protein kinase A via a phosphatidylinositol 4,5-bisphosphate-dependent mechanism. Proceedings of the National Academy of Sciences of the USA 96, 5820-5825.
32. MCGURK, J. F., PONG, S. S., CHAUNG, L. Y., GALL, M., BUTLER, B. & ARENA, J. P. (1993). Growth hormone secretagogues modulate potassium currents in rat somatotrophs. Society for Neuroscience Abstracts 19, part 1, 1559.
33. MARTIN, T. F., HSIEH, K. P. & PORTER, B. W. (1990). The sustained second phase of hormone-stimulated diacylglycerol accumulation does not activate protein kinase C in GH3 cells. Journal of Biological Chemistry 265, 7623-7631.
34. MIHARA, S., NORTH, R. A. & SURPRENANT, A. (1987). Somatostatin increases an inwardly rectifying potassium conductance in guinea-pig submucous plexus neurones. Journal of Physiology 390, 335-355.
35. MULLER, E. E., LOCATELLI, V. & COCCHI, D. (1999). Neuroendocrine control of growth hormone secretion. Physiological Reviews 79, 511-607.
36. + currents in rat spinal cord astrocytes. Journal of Neurophysiology 73, 333-346.
37. ROH, S. G., HE, M. L., MATSUNAGA, N., HIDAKA, S. & HIDARI, H. (1997). Mechanisms of action of growth hormone-releasing peptide-2 in bovine pituitary cells. Journal of Animal Science 75, 2744-2748.
38. SANGUINETTI, M. C., JIANG, C., CURRAN, M. E. & KEATING, M. T. (1995). A mechanistic link between an inherited and an acquired cardiac arrhythmia: HERG encodes the IKr potassium channel. Cell 81, 299-307.
39. SCHAFER, R., WULFSEN, I., BEHRENS, S., WEINSBERG, F., BAUER, C. K. & SCHWARZ, J. R. (1999). The erg-like potassium current in rat lactotrophs. Journal of Physiology 518, 401-416.
40. + currents by thyrotropin-releasing hormone in anterior pituitary cells via the native signal cascade. Journal of Physiology 532, 143-163.
41. + conductance in freshly dispersed rat somatotrophs. Journal of Physiology 441, 615-637.
42. + channels in MIN-6 cells. Journal of Physiology 532, 127-142.
43. SMITH, R. G., LEONARD, R., BAILEY, A. R., PALYHA, O., FEIGHNER, S., TAN, C., MCKEE, K. K., PONG, S. S., GRIFFIN, P. & HOWARD, A. (2001). Growth hormone secretagogue receptor family members and ligands. Endocrine 14, 9-14.
44. + currents in murine brain and endocrine cells. Journal of Physiology 502, 559-567.
45. + current in human growth hormone-secreting adenoma cells. Endocrinology 138, 2405-2409.
46. i in human GH-secreting adenoma cells. American Journal of Physiology 271, E801-807.
47. WALSH, K. B. & KASS, R. S. (1988). Regulation of a heart potassium channel by protein kinase A and C. Science 242, 67-69.
48. + channels by direct protein kinase A-mediated phosphorylation. Proceedings of the National Academy of Sciences of the USA 93, 5819-5823.
49. WU, S. N., LO, Y. K., KUO, B. I. & CHIANG, H. T. (2001). Ceramide inhibits the inwardly rectifying potassium current in GH(3) lactotrophs. Endocrinology 142, 4785-4794.
50. WULFSEN, I., HAUBER, H. P., SCHIEMANN, D., BAUER, C. K. & SCHWARZ, J. R. (2000). Expression of mRNA for voltage-dependent and inward-rectifying K channels in GH3/B6 cells and rat pituitary. Journal of Neuroendocrinology 12, 263-272.
51. XU, R., CLARKE, I. J., CHEN, S. & CHEN, C. (2000). Growth hormone-releasing hormone decreases voltage-gated potassium currents in GH4C1 cells. Journal of Neuroendocrinology 12, 147-157.
52. + currents via a non-cAMP-dependent but PKC-mediated pathway in human GH adenoma cells. Journal of Physiology 520, 697-707.
53. + channel, ROMK, by cyclic AMP-dependent protein kinase. Journal of Biological Chemistry 271, 9313-9319.
54. YAMASHITA, N., SHIBUYA, N. & OGATA, E. (1986). Hyperpolarization of the membrane potential caused by somatostatin in dissociated human pituitary adenoma cells that secrete growth hormone. Proceedings of the National Academy of Sciences of the USA 83, 6198-6202.