Combretastatin-chalcone hybrids: Synthesis and cytotoxicity

Medicinal Chemistry

Volumn 3, Issue 4, 2007, Pages 373-377

  Nam, Nguyen Hai ^a   Byung Zun, Ahn ^b  

^a HANOI UNIVERSITY OF PHARMACY   (Viet Nam)

^b Chungnam National University   (South Korea)

Author keywords

Chalcone; Combretastatin; Cytotoxicity; Synthesis

Indexed keywords

1 (2,5 DIHYDROXYPHENYL) 4 (3,4 DIMETHOXYPHENYL) 5 (4 METHOXYPHENYL) 2,4 PENTANEDIENE 1 ONE; 1 (2,5 DIHYDROXYPHENYL) 4 (4 METHOXYPHENYL) 5 (3,4,5 TRIMETHOXYPHENYL) 2,4 PENTANEDIENE 1 ONE; 1 (2,5 DIHYDROXYPHENYL) 4 (4 METHOXYPHENYL) 5 (4 METHOXYPHENYL) 2,4 PENTANEDIENE 1 ONE; 1 (2,5 DIHYDROXYPHENYL) 4 PHENYL 5 PHENYL 2,4 PENTANEDIENE 1 ONE; 1 (2,5 DIHYDROXYPHENYL) 5 (4 CHLOROPHENYL) 4 (3,4,5 TRIMETHOXYPHENYL) 2,4 PENTANEDIENE 1 ONE; 1 (2,5 DIHYDROXYPHENYL) 5 (4 ETHOXYPHENYL) 4 (3,4,5 TRIMETHOXYPHENYL) 2,4 PENTANEDIENE 1 ONE; 1 (2,5 DIHYDROXYPHENYL) 5 (4 METHOXYPHENYL) 4 (3,4,5 TRIMETHOXYPHENYL) 2,4 PENTANEDIENE 1 ONE; 1 (2,5 DIHYDROXYPHENYL) 5 (4 METHOXYPHENYL) 4 PHENYL 2,4 PENTANEDIENE 1 ONE; 1 (2,5 DIHYDROXYPHENYL) 5 (4 METHYLPHENYL) 4 (3,4,5 TRIMETHOXYPHENYL) 2,4 PENTANEDIENE 1 ONE; 1 (2,5 DIHYDROXYPHENYL) 5 [(3 NITRO 4 METHOXY)PHENYL] 4 (3,4,5 TRIMETHOXYPHENYL) 2,4 PENTANEDIENE 1 ONE; 1 (2,5 DIHYDROXYPHENYL) 5 PHENYL 4 (3,4,5 TRIMETHOXYPHENYL) 2,4 PENTANEDIENE 1 ONE; 1 (4 CHLOROPHENYL) 5 [(3 NITRO 4 METHOXY)PHENYL] 4 (3,4,5 TRIMETHOXYPHENYL) 2,4 PENTANEDIENE 1 ONE; 1 ARYL 4 ARYL 5 ARYL 2,4 PENTANEDIENE 1 ONE; 3 (4 METHOXYPHENYL) 2 (3,4,5 TRIMETHOXYPHENYL)ACRYLIC ACID; 3 (4 METHOXYPHENYL) 2 (3,4,5 TRIMETHOXYPHENYL)PROP 2 EN 1 OL; 3 (4 METHOXYPHENYL) 2 (3,4,5 TRIMETHOXYPHENYL)PROPENAL; 5 [(3 AMINO 4 METHOXY)PHENYL] 1 (2,5 DIHYDROXYPHENYL) 4 (3,4,5 TRIMETHOXYPHENYL) 2,4 PENTANEDIENE 1 ONE; 5 [(3 AMINO 4 METHOXY)PHENYL] 1 (4 CHLOROPHENYL) 4 (3,4,5 TRIMETHOXYPHENYL) 2,4 PENTANEDIENE 1 ONE; 5 [(3 AMINO 4 METHOXY)PHENYL] 1 (4 METHOXYLPHENYL) 4 (3,4,5 TRIMETHOXYPHENYL) 2,4 PENTANEDIENE 1 ONE; 5 [(3 AMINO 4 METHOXY)PHENYL] 1 (4 METHYLPHENYL) 4 (3,4,5 TRIMETHOXYPHENYL) 2,4 PENTANEDIENE 1 ONE; 5 [(3 NITRO 4 METHOXY)PHENYL] 1 (4 METHOXYLPHENYL) 4 (3,4,5 TRIMETHOXYPHENYL) 2,4 PENTANEDIENE 1 ONE; 5 [(3 NITRO 4 METHOXY)PHENYL] 1 (4 METHYLPHENYL) 4 (3,4,5 TRIMETHOXYPHENYL) 2,4 PENTANEDIENE 1 ONE; ANTINEOPLASTIC AGENT; CHALCONE DERIVATIVE; COMBRETASTATIN A4; DOXORUBICIN; METHYL 3 (4 METHOXYPHENYL) 2 (3,4,5 TRIMETHOXYPHENYL)ACRYLIC ACID; UNCLASSIFIED DRUG;

ANIMAL CELL; ANTINEOPLASTIC ACTIVITY; ARTICLE; CANCER CELL CULTURE; COLON CANCER; CONTROLLED STUDY; CYTOTOXICITY; DRUG POTENCY; DRUG STRUCTURE; DRUG SYNTHESIS; ENDOTHELIUM CELL; HUMAN; HUMAN CELL; IN VITRO STUDY; MASS SPECTROMETRY; MELANOMA CELL; NONHUMAN; PRIORITY JOURNAL; PROTON NUCLEAR MAGNETIC RESONANCE; SQUAMOUS CELL CARCINOMA; STRUCTURE ACTIVITY RELATION; THIN LAYER CHROMATOGRAPHY; UMBILICAL VEIN;

BIBENZYLS; CELL LINE; CELL SURVIVAL; CHALCONE; HUMANS; MOLECULAR STRUCTURE; NEOPLASMS; STILBENES; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 34447545619     PISSN: 15734064     EISSN: None     Source Type: Journal    
DOI: 10.2174/157340607781024366     Document Type: Article

References (9)

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