Synthesis, cytotoxicity and antitumor activity of 2,3-diarylcy-clopent-2- ene-1-ones

Archives of Pharmacal Research

Volumn 25, Issue 5, 2002, Pages 600-607

  Nam, Nguyen Hai ^a   Kim, Yong ^a   You, Young Jae ^a   Hong, Dong Ho ^a,b   Kim, Hwan Mook ^b   Ahn, Byung Zun ^a  

^a Chungnam National University   (South Korea)

^b Korea Research Institute of Bioscience and Biotechnology (KRIBB)   (South Korea)

Author keywords

2,3 Diarylcyclopent 2 ene 1 ones; Antitumor activity; Cytotoxicity

Indexed keywords

CYCLOPENTANE DERIVATIVE;

ANIMAL; ARTICLE; DRUG SCREENING; HUMAN; METHODOLOGY; MOUSE; SYNTHESIS;

ANIMALS; CYCLOPENTANES; DRUG SCREENING ASSAYS, ANTITUMOR; HUMANS; MICE;

EID: 0036782545     PISSN: 02536269     EISSN: 02536269     Source Type: Journal    
DOI: 10.1007/BF02976928     Document Type: Article

References (8)

1. Kim, Y., Kim, S. B., You, Y. J., Ahn, B. Z. Deoxypodophyllotoxin; The Cytotoxic and Antiangiogenic Component from Pulsatilla koreana. Planta Med., 68, 271 (2002).
2. Nam, N. H., You, Y. J., Kim, Y., Hong D. H., Kim, H. M., Ahn, B. Z., Combretoxazolones: Syntheses and biological activity. Bioorg. Med. Chem. Lett., 11, 3073-3076 (2001a).
3. Nam, N. H., You, Y. J., Kim, Y., Hong D. H., Kim, H. M., Ahn, B. Z., Syntheses of Certain 3-Aryl-2-propenoates and Evaluation of their Cytotoxicity. Bioorg. Med. Chem. Lett., 11, 1173-1176 (2001b).
4. Nam, N. H., You, Y. J., Kim, Y., Hong D. H., Kim, H. M., Ahn, B. Z., Synthesis and Cytotoxicity of Some Rigid Derivatives of Methyl 2,5-Dihydroxycinnamates. Submitted to Arch. Pharm. Res. (2002a).
5. Nam, N. H., You, Y. J., Kim, Y., Hong D. H., Kim, H. M., Ahn, B. Z., Antitumor, Antiangiogenic and Antiinvasive Activity of the Ephedra Sinica Extract. Phytother. Res., In press (2002b).
6. Nam, N. H., You, Y. J., Kim, Y., Hong D. H., Kim, H. M., Ahn, B. Z., Synthesis and Antitumor Activity of Novel Combretastatins: Combretocyclopentenones and Related Analogues. Bioorg. Med. Chem. Lett., 12, 1955-1958 (2002c).
7. Nam, N. H., You, Y. J., Kim, Y., Hong D. H., Kim, H. M., Ahn, B. Z., Synthesis and Antitumor Activity of Water Soluble Prodrugs of 3-[(3-Amino-4-methoxy)phenyl]-2-(3,4,5-trime-thoxyphenyl)cyclopent-2-ene-1-one. Bioorg. Med. Chem., Submitted (2002d).
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