Hepatotoxic effect of cyclosporin A in the mitochondrial respiratory chain

Journal of Applied Toxicology

Volumn 27, Issue 4, 2007, Pages 310-317

  De La Cruz Rodríguez, Lilia Cristina ^a,b   Araujo, Carmen Rosa ^a   Posleman, Sara Emilia ^a   Rey, María Del Rosario ^a  

^a UNIVERSIDAD NACIONAL DE TUCUMÁN   (Argentina)

^b NONE   (Argentina)

Author keywords

Cyclosporin A; Hepatotoxicity; Mitochondrial respiratory chain

Indexed keywords

CYCLOSPORIN A; EOSIN; GLUTAMATE DEHYDROGENASE; HEMATOXYLIN; IMMUNOSUPPRESSIVE AGENT; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE DEHYDROGENASE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE DEHYDROGENASE (UBIQUINONE); SUCCINATE DEHYDROGENASE; SUCCINATE DEHYDROGENASE (UBIQUINONE); SUCCINIC ACID;

ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DRUG DOSE COMPARISON; ENZYME BLOOD LEVEL; ENZYME INHIBITION; ENZYME SUBSTRATE; LIVER HISTOLOGY; LIVER MITOCHONDRION; LIVER TOXICITY; MALE; NONHUMAN; OXIMETRY; OXYGEN CONSUMPTION; PRIORITY JOURNAL; RAT; RESPIRATORY CHAIN; SPECTROPHOTOMETRY;

ANIMALS; ASPARTATE AMINOTRANSFERASES; BODY WEIGHT; CYCLOSPORINE; DOSE-RESPONSE RELATIONSHIP, DRUG; ELECTRON TRANSPORT COMPLEX I; ELECTRON TRANSPORT COMPLEX II; GLUTAMATE DEHYDROGENASE; HEPATITIS, TOXIC; IMMUNOSUPPRESSIVE AGENTS; LIVER; MALE; MITOCHONDRIA, LIVER; MITOCHONDRIAL MEMBRANES; MULTIENZYME COMPLEXES; NADH, NADPH OXIDOREDUCTASES; ORGAN SIZE; OXYGEN CONSUMPTION; RATS; RATS, WISTAR; TIME FACTORS;

RATTUS; RATTUS NORVEGICUS;

EID: 34447513837     PISSN: 0260437X     EISSN: 10991263     Source Type: Journal    
DOI: 10.1002/jat.1192     Document Type: Article

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