-
1
-
-
0027454175
-
Adrenochrome reaction implicates oxygen radicals in metabolism of cyclosporine A and FK-506 in rat and human liver microsomes
-
Ahmed S.S., Strobel H.W., Napoli K.L., Grevel J. Adrenochrome reaction implicates oxygen radicals in metabolism of cyclosporine A and FK-506 in rat and human liver microsomes. J. Pharm. Exp. Ther. 265:1993;1047.
-
(1993)
J. Pharm. Exp. Ther.
, vol.265
, pp. 1047
-
-
Ahmed, S.S.1
Strobel, H.W.2
Napoli, K.L.3
Grevel, J.4
-
2
-
-
2042501244
-
Glutathione and glutathione delivery compounds
-
Anderson M.E. Glutathione and glutathione delivery compounds. Adv. Pharmacol. 38:1997;65.
-
(1997)
Adv. Pharmacol.
, vol.38
, pp. 65
-
-
Anderson, M.E.1
-
3
-
-
0019978083
-
Toxicity of the immune suppressant cyclosporin A in the rat
-
Blair J.T., Thompson A.W., Whiting P.H., Davidson R.J.L., Simpson J.G. Toxicity of the immune suppressant cyclosporin A in the rat. J. Pathol. 138:1982;163.
-
(1982)
J. Pathol.
, vol.138
, pp. 163
-
-
Blair, J.T.1
Thompson, A.W.2
Whiting, P.H.3
Davidson, R.J.L.4
Simpson, J.G.5
-
4
-
-
0024241497
-
In vitro toxicity assessment of cyclosporin A and its analogs in a primary rat hepatocyte culture model
-
Boelsterli U.A., Bouis P., Brouillard J.-F., Donatsch P. In vitro toxicity assessment of cyclosporin A and its analogs in a primary rat hepatocyte culture model. Toxicol. Appl. Pharmacol. 96:1988;212.
-
(1988)
Toxicol. Appl. Pharmacol.
, vol.96
, pp. 212
-
-
Boelsterli, U.A.1
Bouis, P.2
Brouillard, J.-F.3
Donatsch, P.4
-
5
-
-
0025164832
-
Effect of enzyme induction on sandimmun® (cyclosporin A) biotransformation and hepatotoxicity in cultured rat hepatocytes and in vivo
-
Bouis P., Brouillard J.-F., Fischer V., Donatsch P., Boelsterli U.A. Effect of enzyme induction on sandimmun® (cyclosporin A) biotransformation and hepatotoxicity in cultured rat hepatocytes and in vivo. Biochem. Pharmacol. 39:1990;257.
-
(1990)
Biochem. Pharmacol.
, vol.39
, pp. 257
-
-
Bouis, P.1
Brouillard, J.-F.2
Fischer, V.3
Donatsch, P.4
Boelsterli, U.A.5
-
6
-
-
0017066115
-
Enzymatic assay for glutathione
-
Brehe J.E., Burch H.B. Enzymatic assay for glutathione. Anal. Biochem. 74:1976;189.
-
(1976)
Anal. Biochem.
, vol.74
, pp. 189
-
-
Brehe, J.E.1
Burch, H.B.2
-
8
-
-
0027965108
-
Long-term efficacy and safety of cyclosporine in renaltransplant recipients
-
Burke J.F., Pirsch J.D., Ramos E.L., Salomon D.R., Stablein D.M., van Buren D.H., West J.C. Long-term efficacy and safety of cyclosporine in renaltransplant recipients. New Engl. J. Med. 331:1994;358.
-
(1994)
New Engl. J. Med.
, vol.331
, pp. 358
-
-
Burke, J.F.1
Pirsch, J.D.2
Ramos, E.L.3
Salomon, D.R.4
Stablein, D.M.5
Van Buren, D.H.6
West, J.C.7
-
9
-
-
0027155059
-
Ciclosporin metabolism in transplanted patients
-
Christians U., Sewing K.-Fr. Ciclosporin metabolism in transplanted patients. Pharmacol. Ther. 57:1993;291.
-
(1993)
Pharmacol. Ther.
, vol.57
, pp. 291
-
-
Christians, U.1
Sewing, K.-Fr.2
-
11
-
-
0000080398
-
New tables for multiple comparisons with a control
-
Dunnett C.W. New tables for multiple comparisons with a control. Biometrics. 20:1964;482.
-
(1964)
Biometrics
, vol.20
, pp. 482
-
-
Dunnett, C.W.1
-
12
-
-
0019864790
-
Nature of the toxicity of cyclosporin A in the rat
-
Farthing M.J.G., Clark M.L. Nature of the toxicity of cyclosporin A in the rat. Biochem. Pharmacol. 30:1981;3311.
-
(1981)
Biochem. Pharmacol.
, vol.30
, pp. 3311
-
-
Farthing, M.J.G.1
Clark, M.L.2
-
13
-
-
0019167355
-
Determination of glutathione and glutathione disulfide using glutathione reductase and 2-vinylpyridine
-
Griffith O.W. Determination of glutathione and glutathione disulfide using glutathione reductase and 2-vinylpyridine. Anal. Biochem. 106:1980;207.
-
(1980)
Anal. Biochem.
, vol.106
, pp. 207
-
-
Griffith, O.W.1
-
14
-
-
0004897150
-
Antioxidants: The basics - What they are and how to evaluate them
-
Halliwell B. Antioxidants: the basics - what they are and how to evaluate them. Adv. Pharmacol. 38:1997;3.
-
(1997)
Adv. Pharmacol.
, vol.38
, pp. 3
-
-
Halliwell, B.1
-
16
-
-
0024536206
-
The role for reactive oxygen species in cyclosporin A induced nephrotoxicity in rat
-
Kumano K., Yoshida K., Iwamura M., Endo T., Sakay T., Nakamuara K., Kuwao T. The role for reactive oxygen species in cyclosporin A induced nephrotoxicity in rat. Transplant. Proc. XX. 1:1989;941.
-
(1989)
Transplant. Proc. XX
, vol.1
, pp. 941
-
-
Kumano, K.1
Yoshida, K.2
Iwamura, M.3
Endo, T.4
Sakay, T.5
Nakamuara, K.6
Kuwao, T.7
-
17
-
-
0023684797
-
Cholestatic effect of cyclosporine in the rat
-
Le Thai B., Dumont M., Michel A., Erlinger S., Houssin D. Cholestatic effect of cyclosporine in the rat. Transplantation. 46:1988;510.
-
(1988)
Transplantation
, vol.46
, pp. 510
-
-
Le Thai, B.1
Dumont, M.2
Michel, A.3
Erlinger, S.4
Houssin, D.5
-
18
-
-
0023142190
-
Hepatobiliary and pancreatic complications of cyclosporine therapy in 466 renal transplant recipients
-
Lorber M.I., van Buren C.T., Flechner S.M., Williams C., Kahan B.D. Hepatobiliary and pancreatic complications of cyclosporine therapy in 466 renal transplant recipients. Transplantation. 43:1987;35.
-
(1987)
Transplantation
, vol.43
, pp. 35
-
-
Lorber, M.I.1
Van Buren, C.T.2
Flechner, S.M.3
Williams, C.4
Kahan, B.D.5
-
19
-
-
0027529896
-
Glycine protects hepatocytes from injury caused by anoxia, cold ischemia and mitochondrial inhibitors, but not injury caused by calcium ionophores or oxidative stress
-
Marsh D.C., Vreugdenhil P.K., Mack V.E., Belzer F.O., Southard J.H. Glycine protects hepatocytes from injury caused by anoxia, cold ischemia and mitochondrial inhibitors, but not injury caused by calcium ionophores or oxidative stress. Hepatology. 17:1993;91.
-
(1993)
Hepatology
, vol.17
, pp. 91
-
-
Marsh, D.C.1
Vreugdenhil, P.K.2
MacK, V.E.3
Belzer, F.O.4
Southard, J.H.5
-
20
-
-
0028126537
-
Effects of cyclosporin on kideney glutathione metabolism and cytochrome P-450 in the rabbit: Possible implication of eicosanoid metabolism
-
Massicot F., Thevenin M., Martin C., Warnet J.-M., Duterte-Catella H., Claude J.R. Effects of cyclosporin on kideney glutathione metabolism and cytochrome P-450 in the rabbit: possible implication of eicosanoid metabolism. Drug Chem. Toxicol. 17:1994;449.
-
(1994)
Drug Chem. Toxicol.
, vol.17
, pp. 449
-
-
Massicot, F.1
Thevenin, M.2
Martin, C.3
Warnet, J.-M.4
Duterte-Catella, H.5
Claude, J.R.6
-
21
-
-
0001184687
-
Toxic responses of the liver.
-
In: Klaassen, C.D., Amdur, M.O., Doull, J. (Eds.), McGraw-Hill, New York
-
Moslen, M.T., 1996. Toxic responses of the liver. In: Klaassen, C.D., Amdur, M.O., Doull, J. (Eds.), Casarett and Doull's Toxicology. The Basic Science of Poisons, 5th ed., McGraw-Hill, New York, pp. 403.
-
(1996)
Casarett and Doull's Toxicology. the Basic Science of Poisons, 5th Ed.
, pp. 403
-
-
Moslen, M.T.1
-
22
-
-
0023619257
-
The covalent binding of cyclosporin A to rat liver macromolecules in vivo and in vitro: The role of cytochrome P-450
-
Nagelkerke J.F., Tijdens R.B., Schwarz E.P., Winters M.F.G., Paul L.C., Mulder G.J. The covalent binding of cyclosporin A to rat liver macromolecules in vivo and in vitro: the role of cytochrome P-450. Toxicology. 47:1987;277.
-
(1987)
Toxicology
, vol.47
, pp. 277
-
-
Nagelkerke, J.F.1
Tijdens, R.B.2
Schwarz, E.P.3
Winters, M.F.G.4
Paul, L.C.5
Mulder, G.J.6
-
25
-
-
0020538451
-
Toxicological evaluation of cyclosporin A
-
Ryffel B., Donatsch P., Madorin M., Matter B.E., Rüttimann G., Schon H., Stoll R., Wilson J. Toxicological evaluation of cyclosporin A. Arch. Toxicol. 53:1983;107.
-
(1983)
Arch. Toxicol.
, vol.53
, pp. 107
-
-
Ryffel, B.1
Donatsch, P.2
Madorin, M.3
Matter, B.E.4
Rüttimann, G.5
Schon, H.6
Stoll, R.7
Wilson, J.8
-
26
-
-
0027275820
-
Generation of oxygen free radicals during the metabolism of cyclosporine A: A cause-effect relationship with metabolism inhibition
-
Serino F., Grevel J., Napoli K.L., Kahan B.D., Strobel H.W. Generation of oxygen free radicals during the metabolism of cyclosporine A: a cause-effect relationship with metabolism inhibition. Mol. Cell. Biochem. 122:1993;101.
-
(1993)
Mol. Cell. Biochem.
, vol.122
, pp. 101
-
-
Serino, F.1
Grevel, J.2
Napoli, K.L.3
Kahan, B.D.4
Strobel, H.W.5
-
27
-
-
0025282956
-
Biologic activity of cyclosporine metabolites
-
Sewing K.-Fr., Christians U., Kohlhaw K., Radeke H., Strohmeyer S., Kownatzki R., Budniak J., Schottmann R., Bleck J.S., Almeida V.M.F., Deters M., Wonigeit K., Pichlmayr R. Biologic activity of cyclosporine metabolites. Transplant. Proc. 22:1990;1129.
-
(1990)
Transplant. Proc.
, vol.22
, pp. 1129
-
-
Sewing, K.-Fr.1
Christians, U.2
Kohlhaw, K.3
Radeke, H.4
Strohmeyer, S.5
Kownatzki, R.6
Budniak, J.7
Schottmann, R.8
Bleck, J.S.9
Almeida, V.M.F.10
Deters, M.11
Wonigeit, K.12
Pichlmayr, R.13
-
28
-
-
0023766272
-
Inhibition of taurocholate and ouabain transport in isolated rat hepatocytes by cyclosporin A
-
Stacey N.H., Kotecka B. Inhibition of taurocholate and ouabain transport in isolated rat hepatocytes by cyclosporin A. Gastroenterology. 95:1988;780.
-
(1988)
Gastroenterology
, vol.95
, pp. 780
-
-
Stacey, N.H.1
Kotecka, B.2
-
29
-
-
0023222218
-
Cyclosporin A-induced cholestasis
-
Stone B.G., Udani M., Sanghvi A., Warty V., Plocki K., Bedetti C.D., van Thiel D.H. Cyclosporin A-induced cholestasis. Gastroenterology. 93:1987;344.
-
(1987)
Gastroenterology
, vol.93
, pp. 344
-
-
Stone, B.G.1
Udani, M.2
Sanghvi, A.3
Warty, V.4
Plocki, K.5
Bedetti, C.D.6
Van Thiel, D.H.7
-
30
-
-
0019407238
-
The influence of fasting on the susceptibility of mice to hepatotoxic injury
-
Strubelt O., Dost-Kempf E., Siegers C.-P., Younes M., Volpel M., Preuss U., Dreckmann J.G. The influence of fasting on the susceptibility of mice to hepatotoxic injury. Toxicol. Appl. Pharmacol. 60:1981;66.
-
(1981)
Toxicol. Appl. Pharmacol.
, vol.60
, pp. 66
-
-
Strubelt, O.1
Dost-Kempf, E.2
Siegers, C.-P.3
Younes, M.4
Volpel, M.5
Preuss, U.6
Dreckmann, J.G.7
-
31
-
-
0022499782
-
Influence of extracellular calcium on allyl alcohol-induced hepatotoxicity
-
Strubelt O., Younes M., Pentz R. Influence of extracellular calcium on allyl alcohol-induced hepatotoxicity. Acta Pharmacol. Toxicol. 59:1986;47.
-
(1986)
Acta Pharmacol. Toxicol.
, vol.59
, pp. 47
-
-
Strubelt, O.1
Younes, M.2
Pentz, R.3
-
32
-
-
0023932868
-
Effect of cyclosporin A on cultured human kidney cells
-
Triffilis A.D., Kahng M.W. Effect of cyclosporin A on cultured human kidney cells. Transplant. Proc. XX. 3:1988;717.
-
(1988)
Transplant. Proc. XX
, vol.3
, pp. 717
-
-
Triffilis, A.D.1
Kahng, M.W.2
-
33
-
-
0025033479
-
Evidence that alterations in renal metabolism and lipid peroxidation may contribute to cyclosporine nephrotoxicity
-
Walker R.J., Lazzaro V.A., Duggin G.G., Horvath J.S., Tiller D.J. Evidence that alterations in renal metabolism and lipid peroxidation may contribute to cyclosporine nephrotoxicity. Transplantation. 50:1990;487.
-
(1990)
Transplantation
, vol.50
, pp. 487
-
-
Walker, R.J.1
Lazzaro, V.A.2
Duggin, G.G.3
Horvath, J.S.4
Tiller, D.J.5
-
34
-
-
0024521323
-
Isolation, characterization and in vitro activity of human cyclosporin A metabolites
-
Wallemacq P.E., Lhoest G., Latinne D., de Brnyere M. Isolation, characterization and in vitro activity of human cyclosporin A metabolites. Transplant. Proc. 21:1989;906.
-
(1989)
Transplant. Proc.
, vol.21
, pp. 906
-
-
Wallemacq, P.E.1
Lhoest, G.2
Latinne, D.3
De Brnyere, M.4
-
35
-
-
77957001185
-
Assays of intermediates of the citric acid cycle and related compounds by fluorimetric methods
-
Williamson J.R., Corkey B.E. Assays of intermediates of the citric acid cycle and related compounds by fluorimetric methods. Methods Enzymol. 13:1969;434.
-
(1969)
Methods Enzymol.
, vol.13
, pp. 434
-
-
Williamson, J.R.1
Corkey, B.E.2
-
36
-
-
0023858902
-
The involvement of reactive oxygen species in hypoxic injury to rat liver
-
Younes M., Strubelt O. The involvement of reactive oxygen species in hypoxic injury to rat liver. Res. Commun. Chem. Pathol. Pharm. 59:1988;369.
-
(1988)
Res. Commun. Chem. Pathol. Pharm.
, vol.59
, pp. 369
-
-
Younes, M.1
Strubelt, O.2
-
37
-
-
0024217389
-
Cyanide-induced injury to the isolated perfused rat liver
-
Younes M., Strubelt O. Cyanide-induced injury to the isolated perfused rat liver. Pharmacol. Toxicol. 63:1988;382.
-
(1988)
Pharmacol. Toxicol.
, vol.63
, pp. 382
-
-
Younes, M.1
Strubelt, O.2
-
38
-
-
0025092149
-
Protection by exogenous glutathione against hypoxic and cyanide-induced damage to isolated perfused rat livers
-
Younes M., Strubelt O. Protection by exogenous glutathione against hypoxic and cyanide-induced damage to isolated perfused rat livers. Toxicol. Lett. 50:1990;229.
-
(1990)
Toxicol. Lett.
, vol.50
, pp. 229
-
-
Younes, M.1
Strubelt, O.2
-
39
-
-
0025966565
-
Vanadate-induced toxicity towards isolated perfused rat livers: The role of lipid peroxidation
-
Younes M., Strubelt O. Vanadate-induced toxicity towards isolated perfused rat livers: the role of lipid peroxidation. Toxicology. 66:1991;63.
-
(1991)
Toxicology
, vol.66
, pp. 63
-
-
Younes, M.1
Strubelt, O.2
|