Antifibrotic effect of captopril and enalapril on paraquat-induced lung fibrosis in rats

Journal of Applied Toxicology

Volumn 27, Issue 4, 2007, Pages 342-349

  Ghazi Khansari, Mahmoud ^a   Mohammadi Karakani, Ali ^a,b   Sotoudeh, Masoud ^a   Mokhtary, Parvin ^a   Pour Esmaeil, Ebraheim ^a   Maghsoud, Shirin ^a  

^a TEHRAN UNIVERSITY OF MEDICAL SCIENCES   (Iran)

^b Social Security Organization   (Iran)

Author keywords

Angiotensin converting enzyme inhibitors; Hydroxyproline; Paraquat; Pulmonary fibrosis; Rat

Indexed keywords

CAPTOPRIL; DIPEPTIDYL CARBOXYPEPTIDASE; DIPEPTIDYL CARBOXYPEPTIDASE INHIBITOR; ENALAPRIL; GLUTATHIONE; HYDROXYPROLINE; PARAQUAT;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; ENZYME INHIBITION; HISTOPATHOLOGY; LIPID PEROXIDATION; LUNG FIBROSIS; LUNG PARENCHYMA; MALE; NONHUMAN; PRIORITY JOURNAL; RAT; TREATMENT OUTCOME;

ADMINISTRATION, ORAL; ANGIOTENSIN-CONVERTING ENZYME INHIBITORS; ANIMALS; CAPTOPRIL; COLLAGEN; DOSE-RESPONSE RELATIONSHIP, DRUG; ENALAPRIL; GLUTATHIONE; HERBICIDES; HYDROXYPROLINE; INJECTIONS, INTRAPERITONEAL; LIPID PEROXIDATION; LUNG; MALE; PARAQUAT; PULMONARY ALVEOLI; PULMONARY FIBROSIS; RATS; RATS, WISTAR; TIME FACTORS; TREATMENT OUTCOME;

RATTUS; RATTUS NORVEGICUS;

EID: 34447503424     PISSN: 0260437X     EISSN: 10991263     Source Type: Journal    
DOI: 10.1002/jat.1212     Document Type: Article

References (49)

1. Booz GW, Schorb W, Dostal DE, Conrad KM, Chang KC, Baker KM. 1993. Angiotensin II is a mitogenic in neonatal rat cardiac fibroblast. Circ. Res. 72: 1245-1254.
2. Brilla CG, Reams GP, Maisch B, Weber KT. 1993. Renin-angiotensin system and myocardial collagen matrix remodeling in hypertensive heart disease. In vivo and in vitro studies on collagen matrix regulation. Eur. Heart 14 (Suppl. J): 57-61.
3. Brown NJ, Vaughan DE. 1998. Angiotensin-converting enzyme inhibitors. Circulation 97: 1411-1420.
4. Candan F, Alagozlu H. 2001. Captopril inhibits the pulmonary toxicity of paraquat in rats. Hum. Exp. Toxicol. 20: 637-641.
5. Carre P, Leophone P. 1993. Cytokines in pulmonary fibrosis. Rev. Mal. Respir. 10: 193-207.
6. Chen K, Wei Y, Sharp GC, Braley-Mullen H. 2002. Inhibition of TGF-β by anti-TGF-β antibody or lisinopril reduces thyroid fibrosis in granulomatous experimental autoimmune thyroiditis. J. Immunol. 169: 6530-6538.
7. Chopra M, Beswick H, Clapperton M, Dargie HJ, Smith WE, McMurray J. 1992. Antioxidant effects of angiotensin-converting enzyme (ACE) inhibitors: free radical and oxidant scavenging are sulfhydryl dependent, but lipid peroxidation is inhibited by both sulfhydryl- and nonsulfhydryl-containing ACE inhibitors. J. Cardiovasc. Pharmacol. 19: 330-340.
8. Copland GM, Kolin A, Shulman HS. 1974. Fatal pulmonary intraalveolar fibrosis after paraquat ingestion. N. Engl. J. Med. 291: 290-292.
9. Costa LE, La-Padula P, Lores-Arnaiz S, D'Amico G, Boveris A, Kurnjek ML, Basso N. 2002. Long-term angiotensin II inhibition increases mitochondrial nitric oxide synthase and not antioxidant enzyme activities in rat heart. J. Hypertens. 20: 2487-2494.
10. Darr D, Combs S, Murad S, Pinnell S. 1993. Studies on the inhibition of collagen synthesis in fibroblasts treated with paraquat. Arch. Biochem. Biophys. 306: 267-271.
11. Demedts M, Behr J, Buhl R, Costabel U, Dekhuijzen R, Jansen HM, MacNee W, Thomeer M, Wallaert B, Laurent F, Nicholson AG, Verbeken EK, Verschakelen J, Flower CD, Capron F, Petruzzelli S, De Vuyst P, van den Bosch JM, Rodriguez-Becerra E, Corvasce G, Lankhorst I, Sardina M, Montanari M; IFIGENIA Study Group. 2005. High-dose acetylcysteine in idiopathic pulmonary fibrosis. N. Engl. J. Med. 353: 2229-2242.
12. Esterbauer H, Cheeseman KH. 1990. Determination of aldehydic lipid peroxidation products: malonaldehyde and 4-hydroxynonenal. Methods Enzymol. 186: 407-421.
13. Fonseca C, Abraham D, Black CM. 1999. Lung fibrosis. Springer Semin. Immunopathol 21: 453-474.
14. Forman HJ, Aldrich TK, Posner MA, Fisher AB. 1982. Differential paraquat uptake and redox kinetics of rat granular pneumocytes and alveolar macrophages. J. Pharmacol. Exp. Ther. 221: 428-433.
15. Franklin TJ. 1997. Therapeutic approaches to organ fibrosis. Int. J. Biochem. Cell. Biol. 29: 79-89.
16. Garantziotis S, Steele MP, Schwartz DA. 2004. Pulmonary fibrosis: thinking outside of the lung. J. Clin. Invest. 114: 319-321.
17. Ghazi-Khansari M, Nasiri G, Honarjoo M. 2005. Decreasing the oxidant stress from paraquat in isolated perfused rat lung using captopril and niacin. Arch. Toxicol. 79: 341-345.
18. Green FH. 2002. Overview of pulmonary fibrosis. Chest 122(Suppl 6): 334S-339S.
19. Gross TJ, Hunninghake GW. 2001. Idiopathic pulmonary fibrosis. N. Engl. J. Med. 345: 517-525.
20. Hettiarachchi J, Fernando SS. 1988. Pulmonary fibrosis following paraquat poisoning. Ceylon. Med. J. 33: 141-142.
21. Kaetsu A, Fukushima T, Inoue S, Lim H, Moriyama M. 2001. Role of heat shock protein 60 (HSP60) on paraquat intoxication. J. Appl. Toxicol. 21: 425-430.
22. Kifune K, Takatsu A, Shigeta A, Kuniyoshi N. 1990. Scanning electron microscopic study of rat lungs in experimental chronic paraquat poisoning. Nihon Hoigaku Zasshi 44: 302-313 (Abstract).
23. Kuo CH, Hook JB. 1982. Depletion of renal glutathione content and nephrotoxicity of cephaloridine in rabbit, rats, mice. Toxicol. Appl. Pharmacol. 65: 292-302.
24. Kuwano K, Hagimoto N, Hara N. 2001. Molecular mechanisms of pulmonary fibrosis and current treatment. Curr. Mol. Med. 1: 551-573.
25. Lasky JA, Ortiz LA. 2001. Antifibrotic therapy for the treatment of pulmonary fibrosis. Am. J. Med. Sci. 332: 213-218.
26. Marshall RP, Gohlke P, Chambers RC, Howell DC, Bottoms SE, Unger T, McAnulty RJ, Laurent GJ. 2004. Angiotensin II and the fibroproliferative response to acute lung injury. Am. J. Physiol. Lung. Cell. Mol. Physiol. 286: L156-L164.
27. Marshall RP, McAnulty RJ, Laurent GJ. 1997. The pathogenesis of pulmonary fibrosis: is there a fibrosis gene? Int. J. Biochem. Cell. Biol. 29: 107-120.
28. Masafumi T, Okuyama T. 1994. Effect of paraquat on malondialdehyde level in the rat liver microsome. Arch. Toxicol. 8: 187-192.
29. Mason RJ, Schwarz MI, Hunninghake GW, Musson RA. 1999. NHLBI Workshop Summary. Pharmacological therapy for idiopathic pulmonary fibrosis. Past, present, and future. Am. J. Respir. Crit. Care Med. 160: 1771-1777.
30. Melchiorri D, Reiter RJ, Sewerynek E, Hara M, Chen L, Nistico G. 1996. Paraquat toxicity and oxidative damage. Reduction by melatonin. Biochem. Pharmacol. 51: 1095-1099.
31. Mohammadi-Karakani A, Ghazi-Khansari M, Sotoudeh M. 2006. Lisinopril ameliorates paraquat-induced lung fibrosis. Clin. Chim. Acta 367: 170-174.
32. Molteni A, Moulder JE, Cohen EP, Fish BL, Taylor JM, Veno PA, Wolfe LF, Ward WF. 2001. Prevention of radiation-induced nephropathy and fibrosis in a model of bone marrow transplant by an angiotensin II receptor blocker. Exp. Biol. Med. 226: 1016-1023.
33. Murray RE, Gibson JE. 1972. A comparative study of paraquat intoxication in rats, guinea pigs and monkeys. Exp. Mol. Pathol. 17: 317-325.
34. Nadrous HF, Pellikka PA, Krowka MJ, Swanson KL, Chaowalit N, Decker PA, Ryu JH. 2005. The impact of pulmonary hypertension on survival in patients with idiopathic pulmonary fibrosis. Chest 128: 616S-617S.
35. Ohishi T, Saito H, Tsusaka K, Toda K, Inagaki H, Hamada Y, Kumagai N, Atsukawa K, Ishii H. 2001. Anti-fibrogenic effect of an angiotensin converting enzyme inhibitor on chronic carbon tetrachloride-induced hepatic fibrosis in rats. Hepatol. Res. 21: 147-158.
36. Ozyurt H, Sogut S, Yildirim Z, Kart L, Iraz M, Armutcu F, Temel I, Ozen S, Uzun A, Akyol O. 2004. Inhibitory effect of caffeic acid phenethyl ester on bleomycine-induced lung fibrosis in rats. Clin. Chim. Acta 339: 65-75.
37. Pardo A, Ruiz V, Arreola JL, Ramirez R, Cisneros-Lira J, Gaxiola M, Barrios R, Kala SV, Lieberman MW, Selman M. 2003. Bleomycin-induced pulmonary fibrosis is attenuated in gamma-glutamyl transpeptidase-deficient mice. Am. J. Respir. Crit. Care. Med. 167: 925-932.
38. Reddy GK, Enwemeka CS. 1996. Simplified method for the analysis of hydroxyproline in biological tissue. Clin. Biochem. 9: 225-229.
39. Rocco PR, Negri EM, Kurtz PM, Vasconcellos FP, Silva GH, Capelozzi VL, Romero PV, Zin WA. 2001. Lung tissue mechanics and extracellular matrix remodeling in acute lung injury. Am. J. Respir. Crit. Care. Med. 164: 1067-1071.
40. Rose MS, Smith LL, Wyatt I. 1974. Evidence for energy-dependent accumulation of paraquat into rat lung. Nature 252: 314-315.
41. Saunier C, Schrijen F, Gille JP, Horsky P, Peslin R, Hartemann D, Foliguet B, Lambert H. 1982. Experimental chronic paraquat poisoning. Functional and histopathological pulmonary changes. Bull. Eur. Physiopathol. Respir. 18: 863-876 (Abstract).
42. Suntres ZE. 2002. Role of antioxidants in paraquat toxicity. Toxicology 180: 65-77.
43. Tsukada S, Parsons CJ, Rippe RA. 2006. Mechanisms of liver fibrosis. Clin. Chim. Acta 364: 33-60.
44. Virjeyaratnam GS, Corrin B. 1971. Experimental paraquat poisoning: a histological and electron-optical study of the changes in the lung. J. Pathol. 103: 123-129.
45. Wang R, Ibarra-Sunga O, Verlinski L, Pick R, Uhal BD. 2000. Abrogation of bleomycin-induced epithelial apoptosis and lung fibrosis by captopril or by a caspase inhibitor. Am. J. Physiol. Lung. Cell. Mol. Physiol. 279: L143-L151.
46. Wang HD, Yamaya M, Okinaga S, Jia YX, Kamanaka M, Takahashi H, Guo LY, Ohrui T, Sasaki H. 2002. Bilirubin ameliorates bleomycin-induced pulmonary fibrosis in rats. Am. J. Respir. Crit. Care Med. 165: 406-411.
47. Ward PA, Hunninghake GW. 1998. Lung inflammation and fibrosis. Am. J. Respir. Crit. Care Med. 157: S123-S129.
48. Ward WF, Molteni A, Ts'ao CH, Hinz JM. 1990. Captopril reduces collagen and mast cell accumulation in irradiated rat lung. Int. J. Radiat. Oncol. Biol. Phys. 19: 1405-1409.
49. Wolf G, Haberstroh U, Neilson EG. 1992. Angiotensin II stimulates the proliferation and biosynthesis of type I collagen in cultured murine mesangial cells. Am. J. Pathol. 140: 95-107.