Structural diversity within the mononuclear and binuclear active sites of N-acetyl-D-glucosamine-6-phosphate deacetylase

Biochemistry

Volumn 46, Issue 27, 2007, Pages 7953-7962

  Hall, Richard S ^a   Brown, Shoshana ^b   Fedorov, Alexander A ^c   Fedorov, Elena V ^c   Xu, Chengfu ^a   Babbitt, Patricia C ^b   Almo, Steven C ^c   Raushel, Frank M ^a  

^a TEXAS A AND M UNIVERSITY   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

^c ALBERT EINSTEIN COLLEGE OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AMIDE BONDS; METHYL PHOSPHONATE MOIETY; WATER MOLECULES;

AMINES; CATALYSIS; CHEMICAL BONDS; MOLECULAR INTERACTIONS; ZINC;

ENZYMES;

ACETIC ACID; AMIDE; APOENZYME; ASPARTIC ACID; BACTERIAL ENZYME; CARBONYL DERIVATIVE; DIVALENT CATION; ENZYME INHIBITOR; LEWIS ACID; METHYLPHOSPHONIC ACID; MUTANT PROTEIN; N ACETYLGLUCOSAMINE; N ACETYLGLUCOSAMINE 6 PHOSPHATE DEACETYLASE; N METHYLHYDROXYPHOSPHINYLGLUCOSAMINE 6 PHOSPHATE; PHOSPHATE; PHOSPHINE DERIVATIVE; UNCLASSIFIED DRUG; WATER; ZINC;

ARTICLE; CATALYSIS; CATALYST; CHEMICAL BINDING; CRYSTAL STRUCTURE; ENZYME ACTIVE SITE; ENZYME BINDING; ENZYME STRUCTURE; ENZYME SUBSTRATE; ESCHERICHIA COLI; HYDROGEN BOND; HYDROLYSIS; MOLECULAR INTERACTION; NONHUMAN; PRIORITY JOURNAL; PROTON TRANSPORT; STRUCTURE ANALYSIS; THERMOTOGA MARITIMA; THREE DIMENSIONAL IMAGING; X RAY CRYSTALLOGRAPHY;

AMIDOHYDROLASES; AMINO ACID SEQUENCE; BASE SEQUENCE; BINDING SITES; CRYSTALLOGRAPHY, X-RAY; DNA PRIMERS; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; PHYLOGENY; PROTEIN CONFORMATION; SEQUENCE HOMOLOGY, AMINO ACID; THERMOTOGA MARITIMA;

ESCHERICHIA COLI; THERMOTOGA MARITIMA;

EID: 34447345710     PISSN: 00062960     EISSN: None     Source Type: Journal    
DOI: 10.1021/bi700544c     Document Type: Article

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