The structure of Escherichia coli cytosine deaminase

Journal of Molecular Biology

Volumn 315, Issue 4, 2002, Pages 687-697

  Ireton, Gregory C ^a   McDermott, Gerry ^b   Black, Margaret E ^c   Stoddard, Barry L ^a  

^a UNIVERSITY OF WASHINGTON   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

^c WASHINGTON STATE UNIVERSITY   (United States)

Author keywords

Cytosine deaminase; Enzyme mechanism; Prodrug gene therapy; Protein structure; X ray crystallography

Indexed keywords

ADENOSINE DEAMINASE; ANTIINFECTIVE AGENT; BACTERIAL ENZYME; CYTOSINE; CYTOSINE DEAMINASE; FLUCYTOSINE; FLUOROURACIL; PYRIMIDINE; URACIL;

AMINO ACID SEQUENCE; ARTICLE; CANCER THERAPY; CATALYSIS; CYTOTOXICITY; DEAMINATION; DRUG DESIGN; ENZYME ACTIVE SITE; ENZYME ANALYSIS; ENZYME BINDING; ENZYME CONFORMATION; ENZYME STRUCTURE; ENZYME SUBUNIT; ESCHERICHIA COLI; FUNGUS; GENE THERAPY; PRIORITY JOURNAL; PROKARYOTE; PROTEIN DOMAIN; PROTEIN PROTEIN INTERACTION; STRUCTURE ANALYSIS;

BACTERIA (MICROORGANISMS); ESCHERICHIA COLI; EUKARYOTA; FUNGI; PROKARYOTA;

EID: 0036304598     PISSN: 00222836     EISSN: None     Source Type: Journal    
DOI: 10.1006/jmbi.2001.5277     Document Type: Article

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