Stem cell theory of colorectal cancer and its connection with molecularbiological data;A colorectalis rák kialakulásának ossejtelmélete és összefüggése a molekuláris biológiai adatokkal

Orvosi Hetilap

Volumn 148, Issue 17, 2007, Pages 779-785

  Hagymási, Krisztina ^a,c   Molnár, Béla ^a,b   Sipos, Ferenc ^a,b   Galamb, Orsolya ^a,b   Tulassay, Zsolt ^a,b  

^a SEMMELWEIS UNIVERSITY   (Hungary)

^b INSTITUTE OF EXPERIMENTAL MEDICINE   (Hungary)

^c Semmelweis Egyetem   (Hungary)

Author keywords

Cancer stem cell; Colorectal cancer; Notch; Stem cell; Wnt; Catenin

Indexed keywords

APC PROTEIN; BETA CATENIN; CYCLIN DEPENDENT KINASE INHIBITOR; CYCLIN DEPENDENT KINASE INHIBITOR 2A; MATHUSASHI 1; METHYLATED DNA PROTEIN CYSTEINE METHYLTRANSFERASE; MISMATCH REPAIR PROTEIN PMS2; PROTEIN MLH1; PROTEIN P16; TUMOR MARKER; UNCLASSIFIED DRUG; WNT PROTEIN; NOTCH RECEPTOR;

ARTICLE; CANCER LOCALIZATION; CANCER MORTALITY; CANCER STEM CELL; CARCINOGENESIS; CELL PROLIFERATION; CELL RENEWAL; COLORECTAL CANCER; DNA METHYLATION; GENE MUTATION; HEMATOPOIETIC STEM CELL TRANSPLANTATION; HUMAN; HUNGARY; LIFE CYCLE; MALIGNANT TRANSFORMATION; MOLECULAR BIOLOGY; PREVALENCE; SIGNAL TRANSDUCTION; THEORETICAL STUDY; CELL TRANSFORMATION; COLITIS; COLORECTAL TUMOR; EPITHELIUM CELL; GENE EXPRESSION REGULATION; MALE; METABOLISM; MUTATION; PATHOLOGY; REVIEW;

BETA CATENIN; CELL TRANSFORMATION, NEOPLASTIC; COLITIS; COLORECTAL NEOPLASMS; EPITHELIAL CELLS; GENE EXPRESSION REGULATION, NEOPLASTIC; HUMANS; MALE; MUTATION; RECEPTORS, NOTCH; SIGNAL TRANSDUCTION; TUMOR STEM CELLS; WNT PROTEINS;

EID: 34447322600     PISSN: 00306002     EISSN: 17886120     Source Type: Journal    
DOI: 10.1556/OH.2007.28071     Document Type: Article

References (37)

1. Leedham, S. J., Schier, S., Thliveris, A. T. és mtsai: From gene mutations to tumours - stem cells in gastrointestinal carcinogenesis. Cell Prolif., 2005, 38, 387-405.
2. Tulassay Zs. (szerk.): Gasztroenterológiai Útmutató 2005 - Klinikai Irányelvek Kézikönyve. Medition Kiadó, Budapest. 2005, 133-136.
3. Pinto, D., Clevers, H.: Wnt, stem cells and cancer in the intestine. Biol. Cell, 2005, 97, 185-196.
4. Sipos F., Tihanyi E., Molnár B. és mtsa: Humán szöveti ossejtek izolálása és terápiás alkalmazása. Orv. Hetil., 2005, 146, 1327-1333.
5. Uher F., Vas V.: A szöveti ossejtek plaszticitása. Orv. Hetil., 2002, 18, 921-928.
6. Wright, N.: Stem cell in the GI tract: Where are we now and where are we going? AGA Perspectives, 2006, 2, 6.
7. Kim, K-M., Shibata, D.: Methylation revelas a niche: stem cell succession in human colon crypt. Oncogene, 2002, 21, 5441-5449.
8. Morrison, S. J., Kimble J.: Asymmetric and symmetric stem-cell divisions in development and cancer. Nature, 2006, 441, 1068-1074.
9. McDonald, S. A. C., Preston, S. L., Lowell, M. J. és mtsai: Mechanisms of disease: from stem cell cells to colorectal cancer. Nature Clin. Practice Gastroenterol. Hepatol., 2006, 3, 267-274.
10. Serakinci, N., Keith, W. N.: Therapeutic potential of adult stem cells. Eur. J. Cancer, 2006, 42, 1243-1246.
11. Radtke, F., Clevers, H.: Self-renewal and cancer of the gut: two sides of the coin. Science, 2005, 307, 1904-1909.
12. Scadden, D. T.: The stem-cell niche as an entity of action. Nature, 2006, 441, 1075-1079.
13. Varró V. (Szerk.): Gastroenterologia. Medicina Könyvkiadó Rt., Budapest. 1998, 318-322.
14. Reya, T., Clevers, H.: Wnt signalling in stem cells and cancer. Nature, 2005, 434, 843-850.
15. Silberg, D. G., Wu, G. D.: Development of the alimentary tract, liver and pancreas. In Pathology of gastrointestinal cancers. In Gastrointestinal cancers. Szerk.: Rustgi, A. K., Crawford, J. M. Saunders, New York. 2005, 105-115.
16. Bjerknes, M., Cheng, H.: Gastrointestinal Stem Cells. II. Intestinal stem cells. Am. J. Physiol. Gastrointest. Liver Physiol., 2005, 289, G381-G387.
17. Stanger, B. Z., Datar, R., Murtaugh, L. C. és mtsai: Direct regulation of intestinal fate by Notch. Proc. Natl. Acad. Sci. USA, 2005, 102, 12443-12448.
18. Li, H. C., Stoicov, C., Rogers, A. B. és mtsa: Stem cells and cancer: Evidence for bone marrow stem cells in epithelial cancers. W. J. Gastroent., 2006, 12, 363-371.
19. Marx, J.: Mutant stem cells may seed cancer. Science, 2003, 301, 1308-1310.
20. Galamb O., Molnár B., Sipos F. és mtsa: A humán szöveti (felnott) ossejtek kutatása és klinikai alkalmazási lehetoségei. Orv. Hetil., 2003, 144, 2263-2270.
21. Korbling, M., Katz, R. L., Khanna, A. és mtsai: Hepatocytes and epithelial cells of donor origin in recipients of peripheral-blood stem cells. N. Eng. J. Med., 2002, 346, 738-746.
22. Houghton, J. M., Stoicov, C., Nomura, S. és mtsai: Gastric cancer originating from bone-marrow-derived cells. Science, 2004, 306, 1568-1570.
23. Houghton, J., Wang, T. C.: Helicobacter pylori and gastric cancer: a new paradigm for inflammation-associated epithelial cancers. Gastroenterology, 2005, 128, 1567-1578.
24. Secko, D.: Do stem cells cause gastric cancer? CMAJ, 2005, 172, 325-326.
25. Burkert, J., Wright, N. A., Alison, M. R.: Stem cells and cancer: an intimate relationship. J. Pathol., 2006, 209, 287-297.
26. Hagymási K., Tulassay Zs.: Gyulladásos bélbetegségek és colorectalis rák. Orv. Hetil., 2006, 147, 1977-1982.
27. Rhodes, J. M., Campbell, B. J.: Inflammation and colorectal cancer: IBD-associated and sporadic cancer compared. TRENDS Mol. Med., 2002, 8, 10-16.
28. Jackson, L., Evers, B. M.: Chronic inflammation and athogenesis of GI and pancreatic cancer. Cancer Treat. Res., 2006, 130, 39-65.
29. Schottelius, A. J., Dinter, H.: Cytokines, NF-kappaB, microenvironment, intestinal inflammation and cancer. Cancer Treat. Res., 2006, 130, 67-87.
30. Wang, W. S., Chen, P. M. és Su, Y.: Colorectal carcinoma: from tumorigenesis to treatment. Cell. Mol. Life Sci., 2006, 63, 663-671.
31. Jubb, A. M., Bell, S. M., Quirke, P.: Methylation and colorectal cancer. J. Pathol., 2001, 195, 111-134.
32. Ogino, S., Odze, R. D., Kawasaki, T. és mtsai: Correlation of pathologic features with CpG island methylator phenotype (CIMP) by quantitative DNA methylation analysis in colorectal carcinoma. Am. J. Surg. Pathol., 2006, 30, 1175-1183.
33. Jass, J. R.: Serated adenoma of the colorectum and the DNA-methylator phenotype. Nat. Clin. Pract. Oncol., 2005, 2, 398-405.
34. Tupurainen, K., Makinen, J. M., Junttila, O. és mtsai: Morphology and microsatellite instability in sporadic serrated and non-serrated colorectal cancer. J. Pathol., 2005, 207, 285-294.
35. Gregorieff, A., Clevers, H.: Wnt signaling in the intestinal epithelium: from endoderm to cancer. Genes Dev., 2005, 19, 877-890.
36. Pinto, D., Clevers, H.: Wnt control of stem cell and differentiation in the intestinal epithelium. Exp. Cell Res., 2005, 306, 357-363.
37. Holmberg, J., Genander, M., Halford, M. M. és mtsai: EphB receptors coordinate migration and proliferation in the intestinal stem cell niche. Cell, 2006, 125, 1151-1163.