A plateau in pre-Alzheimer memory decline: Evidence for compensatory mechanisms?

Neurology

Volumn 69, Issue 2, 2007, Pages 133-139

  Smith, G E ^a,c   Pankratz, V S ^b,c   Negash, S ^a,c   Machulda, M M ^a,c   Petersen, R C ^a,c   Boeve, B F ^a,c   Knopman, D S ^a,c   Lucas, J A ^a,d   Ferman, T J ^a,d   Graff Radford, N ^a,d   Ivnik, R J ^a,c  

^a Department of Psychiatry and Psychology ^*  (United States)

^b Division of Biostatistics   (United States)

^c MAYO CLINIC   (United States)

^d MAYO CLINIC   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ADULT; AGED; ALZHEIMER DISEASE; ARTICLE; COGNITION; CONTROLLED STUDY; FEMALE; HUMAN; MAJOR CLINICAL STUDY; MALE; MEMORY DISORDER; NERVE CELL NETWORK; NEUROPSYCHOLOGICAL TEST; NEUROTRANSMITTER RELEASE; PRIORITY JOURNAL; SCORING SYSTEM; STATISTICAL MODEL; UPREGULATION;

ADAPTATION, PHYSIOLOGICAL; AGE FACTORS; AGED; AGED, 80 AND OVER; ALZHEIMER DISEASE; BRAIN; COMORBIDITY; DISEASE PROGRESSION; FEMALE; HUMANS; LOGISTIC MODELS; LONGITUDINAL STUDIES; MALE; MEMORY DISORDERS; MODELS, STATISTICAL; NEURONAL PLASTICITY; NEUROPSYCHOLOGICAL TESTS; PREDICTIVE VALUE OF TESTS; PROGNOSIS;

EID: 34447318881     PISSN: 00283878     EISSN: None     Source Type: Journal    
DOI: 10.1212/01.wnl.0000265594.23511.16     Document Type: Article

References (46)

1. Bäckman L, Small B, Fratiglioni L. Stability of the preclinical episodic memory deficit in Alzheimer's disease. Brain 2001;124:96-102.
2. Bondi M, Salmon D, Galasko D, Thomas R, Thal L. Neuropsychological function and apolipoprotein E genotype in the preclinical detection of Alzheimer's disease. Psychol Aging 1999;14:295-303.
3. Chen P, Ratcliff G, Belle S, et al. Patterns of cognitive decline in presymptomatic Alzheimer disease: a prospective community study. Arch Gen Psychiatry 2001;58:853-858.
4. Fuld P, Masur D, Blau A, Crystal H, Aronson M. Object-memory evaluation for prospective detection of dementia in normal functioning elderly: predictive and normative data. J Clin Exp Neuropsychol 1990;12:520-528.
5. Jacobs D, Sano M, Dooneief G, et al. Neuropsychological detection and characterization of preclinical Alzheimer's disease. Neurology 1995;45:957-962.
6. Lange K, Bondi M, Salmon D, et al. Decline in verbal memory during preclinical Alzheimer's disease: examination of the effect of APOE genotype. J Int Neuropsychol Soc 2002;8:943-955.
7. Masur D, Sliwinski M, Lipton R, Blau A, Crystal H. Neuropsychological prediction of dementia and the absence of dementia in healthy elderly persons. Neurology 1994;44:1427-1432.
8. Petersen R, Smith G, Waring S, et al. Mild cognitive impairment: clinical characterization and outcome. Arch Neurol 1999;56:303-308.
9. Smith G, Petersen R, Parisi J, et al. Definition, course and outcome of mild cognitive impairment. Aging Neuropsychol Cogn 1996;3:141-147.
10. Small B, Mobly J, Laukka E, Jones S, Backman L. Cognitive deficits in preclinical Alzheimer's disease. Acta Neurol Scand (Suppl) 2003;179:29-33.
11. Cerhan J, Ivnik R, Smith G, et al. Alzheimer's disease patients' cognitive status and course years prior to symptom recognition. Aging Neuropsychol Cogn 2007;14:227-235.
12. Petersen R. Mild cognitive impairment as a diagnostic entity. J Intern Med 2004;256:183-194.
13. Hall C, Ying J, Kuo L, Lipton R. Bayesian and profile likelihood change point methods for modeling cognitive function over time. Comput Stat Data Anal 2003;42:91-109.
14. Twamley E, Ropacki S, Bondi M. Neuropsychological and neuroimaging changes in preclinical Alzheimer's disease. J Int Neuropsychol Soc 2006;12:707-735.
15. McKhann G, Drachman D, Folstein M, et al. Clinical diagnosis of Alzheimer's disease: Report of the NINCDS-ADRDA work group under the auspices of Department of Health and Human Services Task Force on Alzheimer's Disease. Neurology 1984;34:939-944.
16. Malec J, Ivnik R, Smith G. Neuropsychology and normal aging: clinicians' perspective. In: Parks R, Zec R, Wilson R, eds. Neuropsychology of Alzheimer's disease and related dementias. New York: Oxford University Press, 1993:81-111.
17. Smith G, Ivnik R, Malec J, et al. Mayo Cognitive Factor Scales: derivation of a short battery and norms for factor scores. Neuropsychology 1994;8:194-202.
18. Wechsler D. Wechsler Adult Intelligence Scale-Revised. New York: Psychological Corporation, 1981.
19. Wechsler D. Wechsler Memory Scale-Revised. New York: Psychological Corporation, 1987.
20. Rey A. L'examen clinique en psychologie. Paris: Presses Universitaires de France, 1964.
21. DeKosky S, Ikonomovic M, Styren S, et al. Upregulation of choline acetyltransferase activity in hippocampus and frontal cortex of elderly subjects with mild cognitive impairment. Ann Neurol 2002;51:145-155.
22. Ikonomovic M, Mufson E, Wuu J, Bennett D, DeKosky S. Reduction of choline acetyltransferase activity in primary visual cortex in mild to moderate Alzheimer's disease. Arch Neurol 2005;62:425-430.
23. Davis K, Mohs R, Marin D, et al. Cholinergic markers in elderly patients with early signs of Alzheimer disease. JAMA 1999;281:1401-1406.
24. Gilmor M, Erickson J, Varoqui H, et al. Preservation of nucleus basalis neurons containing choline acetyltransferase and the vesicular acetylcholine transporter in the elderly with mild cognitive impairment and early Alzheimer's disease. J Comp Neurol 1999;411:693-704.
25. Durany N, Michel T, Kurt J, et al. Brain-derived neurotrophic factor and neurotrophin-3 levels in Alzheimer's disease brains. Int J Dev Neurosci 2000;18:807-813.
26. Egan M, Kojima M, Callicott J, et al. The BDNF val66met polymorphism affects activity-dependent secretion of BDNF and human memory and hippocampal function. Cell 2003;112:257-269.
27. Mufson E, Ikonomovic M, Styren S, et al. Preservation of brain nerve growth factor in mild cognitive impairment and Alzheimer disease. Arch Neurol 2003;60:1143-1148.
28. Peng S, Wuu J, Mufson E, Fahnestock M. Increased proNGF levels in subjects with mild cognitive impairment and mild Alzheimer disease. J Neuropathol Exp Neurol 2004;63:641-649.
29. Grady C, McIntosh A, Beig S, et al. Evidence from functional neuroimaging of a compensatory prefrontal network in Alzheimer's disease. J Neurosci 2003;23:986-993.
30. Dickerson B, Salat D, Bates J, et al. Medial temporal lobe function and structure in mild cognitive impairment. Ann Neurol 2004;56:27-35.
31. Dickerson B, Salat D, Greve D, et al. Increased hippocampal activation in mild cognitive impairment compared to normal aging and AD. Neurology 2005;65:404-411.
32. Heun R, Freymann K, Erb M, et al. Mild cognitive impairment (MCI) and actual retrieval performance affect cerebral activation in the elderly. Neurobiol Aging 2006;available on-line.
33. Celone K, Calhoun V, Dickerson B, et al. Alterations in memory networks in mild cognitive impairment and Alzheimer's disease: an independent component analysis. J Neurosci 2006;26:10222-10231.
34. Johnson S, Baxter L, Susskind-Wilder L, et al. Hippocampal adaptation to face repetition in healthy elderly and mild cognitive impairment. Neuropsychologia 2004;42:980-989.
35. Rombouts S, Goekoop R, Stam C, Barkhof F, Scheltens P. Delayed rather than decreased BOLD response as a marker for early Alzheimer's disease. Neuroimage 2005;26:1078-1085.
36. Ries M, Schmitz T, Kawahara T, et al. Task-dependent posterior cingulate activation in mild cognitive impairment. Neuroimage 2006;29:485-492.
37. Machulda M, Ward H, Borowski B, et al. Comparison of memory fMRI response among normal, MCI, and Alzheimer's patients. Neurology 2003;61:500-506.
38. Petrella J, Krishnan S, Slavin M, et al. Mild cognitive impairment: evaluation with 4-T functional MR imaging. Radiology 2006;240:177-186.
39. Scheff S, Price D. Alzheimer's disease-related alterations in synaptic density: neocortex and hippocampus. J Alzheimers Dis 2006;9(suppl 3);101-115.
40. Petersen R, Parisi J, Dickson D, et al. Neuropathologic features of amnestic mild cognitive impairment. Arch Neurol 2006;63:665-672.
41. Stern Y. Cognitive reserve and Alzheimer's disease. Alzheimer Dis 2006;20:112-117.
42. Ivnik R, Smith G, Petersen R, et al. Diagnostic accuracy of four approaches to interpreting neuropsychological test data. Neuropsychologia 2000;14:163-177.
43. Akwa Y, Allain H, Bentue-Ferrer D, et al. Neuroprotection and neurodegenerative diseases: from biology to clinical practice. Alzheimer Dis 2005;19:226-239.
44. Greenaway M, Smith G, Lepore S, et al. Compensating for memory loss in amnestic mild cognitive impairment. Alzheimers Dementia 2006;2(suppl 1):S571.
45. Powell M, Smith G, Knopman D, et al. Cognitive measures predict Alzheimer's disease pathology. Arch Neurol 2006;63:865-868.
46. Petersen RC. Aging, mild cognitive impairment, and Alzheimer's disease. In: DeKosky S, ed. Neurologic clinics. Philadelphia: Saunders, 2000:789-805.