Triplex molecular beacons as modular probes for DNA detection

Angewandte Chemie - International Edition

Volumn 46, Issue 27, 2007, Pages 5223-5225

  Grossmann, Tom N ^a   Röglin, Lars ^a   Seitz, Oliver ^a  

^a HUMBOLDT UNIVERSITY   (Germany)

Author keywords

Bioanalysis; DNA recognition; Fluorescent probes; FRET (fluorescence resonant energy transfer); Molecular beacons

Indexed keywords

BIOANALYSIS; FLUORESCENCE RESONANT ENERGY TRANSFER (FRET); FLUORESCENT PROBES; MODULAR PROBES; MOLECULAR BEACONS; QUENCHERS;

DNA; ENERGY TRANSFER; FLUOROPHORES; MOLECULAR RECOGNITION; OLIGOMERS;

BIOSENSORS;

DNA;

ARTICLE; CHEMISTRY; CONFORMATION; DNA DENATURATION; MOLECULAR PROBE; TEMPERATURE; TRANSITION TEMPERATURE;

DNA; MOLECULAR PROBES; NUCLEIC ACID CONFORMATION; NUCLEIC ACID DENATURATION; TEMPERATURE; TRANSITION TEMPERATURE;

EID: 34447310597     PISSN: 14337851     EISSN: None     Source Type: Journal    
DOI: 10.1002/anie.200700289     Document Type: Article

References (23)

1. a) C. A. Foy, H. C. Parkes, Clin. Chem. 2001, 47, 990-1000;
2. b) R. T. Ranasinghe, T. Brown, Chem. Commun. 2005, 5487-5502.
3. a) S. Tyagi, F. R. Kramer, Nat. Biotechnol. 1996, 14, 303-308;
4. b) selected review: W. Tan, K. Wang, T. J. Drake, Curr. Opin. Chem. Biol. 2004, 8, 547-553.
5. G. Bonnet, S. Tyagi, A. Libchaber, F. R. Kramer, Proc. Natl. Acad. Sci. USA 1999, 96, 6171-6176.
6. a) C. Crey-Desbiolles, D. Ahn, C. Leumann, Nucleic Acids Res. 2005, 33, e77;
7. b) L. Wang, C. J. Yang, C. D. Medley, S. A. Benner, W. Tan, J. Am. Chem. Soc. 2005, 127, 15 664-15 665;
8. c) A. Bourdoncle, A. Estevez Torres, C. Gosse, L. Lacroix, P. Vekhoff, T. Le Saux, L. Jullien, J.-L. Mergny, J. Am. Chem. Soc. 2006, 128, 11 094-11 105;
9. d) O. Seitz, Angew. Chem. 2000, 112, 3389-3392;
10. Angew. Chem. Int. Ed. 2000, 39, 3249-3252;
11. e) H. Kuhn, V. V. Demidov, B. D. Gildea, J. M. Fiandaca, J. C. Coull, M. D. Frank-Kamenetskii, Antisense Nucleic Acid Drug Dev. 2001, 11, 265-270;
12. f) H. Kuhn, V. V. Demidov, J. C. Coull, J. M. Fiandaca, B. D. Gildea, M. D. Frank-Kamenetskii, J. Am. Chem. Soc. 2002, 124, 1097-1103.
13. I. Trkulja, S. M. Biner, S. M. Langenegger, R. Häner, Chem BioChem 2007, 8, 25-27.
14. C. J. Yang, H. Lin, W. Tan, J. Am. Chem. Soc. 2005, 127, 12 772-12 774.
15. M. D. Frank-Kamenetskii, S. M. Mirkin, Annu. Rev. Biochem. 1995, 64, 65-95.
16. a) P. Nielsen, M. Egholm, R. Berg, O. Buchardt, Science 1991, 254, 1497-1500;
17. b) selected review: P. E. Nielsen, Curr. Opin. Biotechnol. 2001, 12, 16-20.
18. R.A.J. Darby, M. Sollogoub, C. McKeen, L. Brown, A. Risitano, N. Brown, C. Barton, T. Brown, K. R. Fox. Nucleic Acids Res. 2002, 30, 39e.
19. S. A. E. Marras, F. R. Kramer, S. Tyagi, Nucleic Acids Res. 2002, 30, 122e.
20. a) D. J. French, C. L. Archard, T. Brown, D. G. McDowell, Mol. Cell. Probes 2001, 15, 363-374;
21. b) N. Svanvik, A. Stahlberg, U. Sehlstedt, R. Sjoback, M. Kubista, Anal. Biochem. 2000, 287, 179-182;
22. c) O. Köhler, O. Seitz, Chem. Commun. 2003, 2938-2939;
23. d) O. Köhler, D. V. Jarikote, O. Seitz, ChemBioChem 2005, 6, 69-77.