Impact of Sex, Metabolic Syndrome, and Diabetes Mellitus on Cardiovascular Events

American Journal of Cardiology

Volumn 100, Issue 2, 2007, Pages 227-233

  Mak, Koon Hou ^a   Ma, Stefan ^b   Heng, Derrick ^b   Tan, Chee Eng ^a   Tai, E Shyong ^c   Topol, Eric J ^d   Chew, Suok Kai ^b  

^a GLENEAGLES HOSPITAL   (Singapore)

^b MINISTRY OF HEALTH   (Singapore)

^c SINGAPORE GENERAL HOSPITAL   (Singapore)

^d SCRIPPS RESEARCH INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ADULT; AGED; ARTICLE; CARDIOVASCULAR DISEASE; CONFIDENCE INTERVAL; DIABETES MELLITUS; FEMALE; GENDER; HEALTH SURVEY; HIGH RISK POPULATION; HOSPITAL ADMISSION; HUMAN; ISCHEMIC HEART DISEASE; MAJOR CLINICAL STUDY; MALE; METABOLIC SYNDROME X; MORTALITY; PREVALENCE; PRIORITY JOURNAL; RISK ASSESSMENT; RISK FACTOR; SEX DIFFERENCE; SINGAPORE; STROKE;

ADOLESCENT; ADULT; AGED; CARDIOVASCULAR DISEASES; COHORT STUDIES; DIABETES COMPLICATIONS; FEMALE; HUMANS; MALE; METABOLIC SYNDROME X; MIDDLE AGED; PROSPECTIVE STUDIES; RISK FACTORS; SEX FACTORS;

EID: 34447293482     PISSN: 00029149     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.amjcard.2007.02.090     Document Type: Article

References (28)

1. Isomaa B., Almgren P., Tuomi T., Forsén B., Lahti K., Nissén M., Taskinen M.R., and Groop L. Cardiovascular morbidity and mortality associated with the metabolic syndrome. Diabetes Care 24 (2001) 683-689
2. Lakka H.M., Laaksonen D.E., Lakka T.A., Niskanen L.K., Kumpusalo E., Tuomilehto J., and Salonen J.T. The metabolic syndrome and total and cardiovascular disease mortality in middle-aged men. JAMA 288 (2002) 2709-2716
3. Sattar N., Gaw A., Scherbakova O., Ford I., O'Reilly D.S.J., Haffner S.M., Isles C., Macfarlane P.W., Packard C.J., Cobbe S.M., and Shepherd J. Metabolic syndrome with and without C-reactive protein as a predictor of coronary heart disease and diabetes in the West of Scotland Coronary Prevention Study. Circulation 108 (2003) 414-419
4. Yusuf S., Hawken S., Ôunpuu S., Dans T., Avezum A., Lanas F., McQueen M., Budaj A., Pais P., Varigos J., Lisheng L., and INTERHEART Study Investigators. Effect of potentially modifiable risk factors associated with myocardial infarction in 52 countries (the INTERHEART study): case-control study. Lancet 364 (2004) 937-952
5. Yusuf S., Hawken S., Ônpuu S., Bautista L., Franzosi M.G., Commerford P., Lang C.C., Rumboldt Z., Onen C.L., Lisheng L., et al., INTERHEART Study Investigators. Obesity and the risk of myocardial infarction in 27 000 participants from 52 countries: a case-control study. Lancet 366 (2005) 1640-1649
6. Marroquin O.C., Kip K.E., Kelly D.E., Johan B.D., Shaw L.J., Merz C.N.B., Sharaf B.L., Pepine J.C., Sopko G., Reis S., and Women's Ischemia Syndrome Evaluation Investigators. Metabolic syndrome modifies the cardiovascular risk associated with angiographic coronary artery disease in women: a report from the for the Women's Ischemia Syndrome Evaluation. Circulation 109 (2004) 714-721
7. Ma S., Cutter J., Tan C.E., Chew S.K., and Tai E.S. Associations of diabetes mellitus and ethnicity with mortality in a multiethnic Asian population: data from the 1992 Singapore National Health Survey. Am J Epidemiol 158 (2003) 543-552
8. Joint National Committee on Prevention, Detection, Evaluation, and Treatment of Hypertension. The sixth report of the Joint National Committee on Prevention, Detection, Evaluation, and Treatment of Hypertension. Arch Intern Med 157 (1997) 2413-2446
9. Adult Treatment Panel III. Executive Summary of the Third Report of the National Cholesterol Education Program (NCEP) Expert Panel on Detection, Evaluation, and Treatment of High Blood Cholesterol in Adults (Adult Treatment Panel III). JAMA 285 (2001) 2486-2497
10. Hughes K., Lun K.C., and Yeo P.P.B. Cardiovascular diseases in Chinese, Malays, and Indians in Singapore. I: differences in mortality. J Epidemiol Community Health 44 (1990) 24-28
11. Alexander C.M., Landsman P.B., Teutsch S.M., and Haffner S.M. NCEP-defined metabolic syndrome, diabetes, and prevalence of coronary heart disease among NHANES III participants age 50 years and older. Diabetes 52 (2003) 1210-1214
12. Girman C.J., Rhodes T., Mercuri M., Pyörälä K., Kjekshus J., Pedersen T.R., Beere P.A., Gotto A.M., Clearfield M., 4S Group, and AFCAPS/TexCAPS Research Group. The metabolic syndrome and the risk of major coronary events in the Scandinavian Simvastatin Survival Study (4S) and the Air Force/Texas Coronary Atherosclerosis Prevention Study (AFCAPS/TexCAPS). Am J Cardiol 93 (2004) 136-141
13. Sundström J., Risérus U., Byberg L., Zethelius B., Lithell H., and Lind L. Clinical value of the metabolic syndrome for long term prediction of total and cardiovascular mortality: prospective, population based cohort study. Br Med J 332 (2006) 878-882
14. Resnick H.E., Jones K., Ruotolo G., Jain A.K., Henderson J., Lu W., and Howard B.V. Insulin resistance, the metabolic syndrome, and risk of incident cardiovascular disease in nondiabetic American Indians. The Strong Heart Study. Diabetes Care 26 (2003) 861-867
15. Malik S., Wong N.D., Franklin S.S., Kamath T.V., L'Italien G.L., Pio J.R., and Williams G.R. Impact of the metabolic syndrome on mortality from coronary heart disease, cardiovascular disease, and all causes in United States adults. Circulation 110 (2004) 1245-1250
16. He Y., Jiang B., Wang J., Feng K., Chang Q., Fan L., Li X., and Hu F.B. Prevalence of the metabolic syndrome and its relation to cardiovascular disease in an elderly Chinese population. J Am Coll Cardiol 47 (2006) 1588-1594
17. Anand S.S., Yi Q., Gerstein H., Lonn E., Jacobs R., Vuksan V., Teo K., Davis B., Montague P., Yusuf S., Study of Health Assessment and Risk in Ethnic groups (SHARE), and Study of Health Assessment and Risk Evaluation in Aboriginal Peoples (SHARE-AP) Investigators. Relationship of metabolic syndrome and fibrinolytic dysfunction to cardiovascular disease. Circulation 108 (2003) 420-425
18. Hulthe J., Bokemark L., Wikstrand J., and Fagerberg B. The metabolic syndrome, LDL particle size, and atherosclerosis: the Atherosclerosis and Insulin Resistance (AIR) study. Arterioscler Thromb Vasc Biol 20 (2000) 2140-2147
19. Lakka H.M., Lakka T.A., Tuomilehto J., and Salonen J.T. Abdominal obesity is associated with increased risk of acute coronary events in men. Eur Heart J 23 (2002) 705-714
20. Regitz-Zagrosek V., Lehmkuhl E., and Weickert M.O. Gender differences in the metabolic syndrome and their role for cardiovascular disease. Clin Res Cardiol 95 (2006) 136-147
21. Kip K.E., Marroquin O.C., Kelly D.E., Johnson B.D., Kelsey S.F., Shaw L.J., Rogers W.J., and Reis S.E. Clinical importance of obesity versus the metabolic syndrome in cardiovascular risk in women: a report from the Women's Ischemia Syndrome Evaluation (WISE) Study. Circulation 109 (2004) 706-713
22. Carr M.C., Hokanson J.E., Zambon A., Deeb S.S., Barrett P.H.R., Purnell J.Q., and Brunzell J.D. The contribution of intraabdominal fat to gender differences in hepatic lipase activity and low/high density lipoprotein heterogeneity. J Clin Endocrinol Metab 86 (2001) 2831-2837
23. Couillard C., Bergeron N., Prud'homme D., Bergeron J., Tremblay A., Bouchard C., Mauriège P., and Després J.P. Gender difference in postprandial lipidemia. Importance of visceral adipose tissue accumulation. Arterioscler Thromb Vasc Biol 19 (1999) 2448-2455
24. Liao Y., Cooper R.S., Mensah G.A., and McGee D.L. Left ventricular hypertrophy has a greater impact on survival in women than in men. Circulation 92 (1995) 805-810
25. Evans R.W., and Orchard T.J. Oxidized lipids in insulin-dependent diabetes mellitus: a sex-diabetes interaction?. Metabolism 43 (1994) 1196-1200
26. Steinberg H.O., Paradisi G., Cronin J., Crowde K., Hempfling A., Hook G., and Baron A.D. Type II diabetes abrogates sex differences in endothelial function in premenopausal women. Circulation 101 (2000) 2040-2046
27. Klein B.E.K., Klein R., and Lee K.E. Components of the metabolic syndrome and risk of cardiovascular disease and diabetes in Beaver Dam. Diabetes Care 25 (2002) 1790-1794
28. Lichnovská R., Gwozdziewiczová S., and Hrebícek J. Gender differences in factors influencing insulin resistance in elderly hyperlipemic non-diabetic subjects. Cardiovasc Diabetol 1 (2002) 4