X-ray structure of HIV-1 protease tethered dimer complexed to ritonavir

Protein and Peptide Letters

Volumn 14, Issue 6, 2007, Pages 565-568

  Das, Amit ^a   Rao, Dharmaraj Ramachandra ^b   Hosur, Madhusoodan Vijayacharya ^a  

^a BHABHA ATOMIC RESEARCH CENTRE   (India)

^b CIPLA LTD   (India)

Author keywords

HIV 1 protease; Inhibitor; Tethered dimmer; X ray crystallography

Indexed keywords

HUMAN IMMUNODEFICIENCY VIRUS; HUMAN IMMUNODEFICIENCY VIRUS 1;

EID: 34447287560     PISSN: 09298665     EISSN: None     Source Type: Journal    
DOI: 10.2174/092986607780989930     Document Type: Article

References (18)

1. Heagarty, M.C. (2003) AIDS: The Battle Rages On, Issues in science and technology online, Summer 2003, http://www.nap.edu/issues/19.4/heagarty. html#top.
2. Kohl, N.E., Emini, E.A., Schleif, W.A., Davis, L.J., Heimbach, J.C., Dixon, R.A.E., Scolnick, M. and Sigal, I.S. (1988) Proc. Natl. Acad. Sci. USA, 85, 4686-4690.
3. Wolfenden, R. (1999) Bioorg. Med. Chem., 7, 647-652.
4. Wlodawer, A. and Vondrasek, J. (1998) Annu. Rev. Biophys. Biomol. Struct., 27, 249-284.
5. Prashar, V. and Hosur, M.V. (2004) Biochem. Biophys. Res. Commun., 323, 1229-1235.
6. Cheng, Y.-S.E.F. and Yin, H., Foundling, S., Blomstrom, D. and Kettner, C.A. (1990) Proc. Natl. Acad. Sci. USA, 87, 9660-9664.
7. Kumar, M., Prashar, V., Mahale, S. and Hosur, M.V. (2005) Biochem. J., 389(2), 365-371.
8. Das, A., Prashar, V., Mahale, S., Serre, L., Ferrer, J.-L. and Hosur, M.V. (2006) Proc. Natl. Acad. Sci. USA, 103(49), 18464-18469.
9. http://www.hivdb.stanford.edu
10. Wlodawer, A. and Erickson, J.W. (1993) Annu. Rev. Biochem., 62, 543-585.
11. Kumar, M., Kannan, K.K., Hosur, M.V., Bhavesh, N.S., Chatterjee, A., Mittal, R. and Hosur, R.V. (2002) Biochem. Biophys. Res. Commun., 294, 395-401.
12. Vondrasek, J. and Wlodawer, A. (2002) Proteins Struct. Funct. Genet., 49, 429-431.
13. Jaskolski, M., Tomasselli, A.G., Sawyer, T.K., Staples, D.G., Heinrickson, R.L., Schneider, J., Kent, S.B.H. and Wlodawer, A. (1991) Biochemistry, 30, 1600-1609.
14. Pillai, B., Kannan, K., K. and Hosur, M.V. (2001) Proteins, 43, 57-64.
15. Otwinowski, Z. (1993) "Oscillation Data Reduction Program" in Proceedings of the CCP4 study weekend: "Data Collection and Processing", Compiled by Swyer, L., Isaacs, N. Bailys SERC Daresbury Laboratory England. pp. 56-62.
16. Brünger, A.T., Adams, P.D., Clore, G.M., DeLano, W.L., Gros, P., Grosse-Kunstleve, R.W., Jiang, J.-S., Kuszewski, J., Nilges, M., Pannu, N.S., Read, R.J., Rice, L.M., Simonson, T. and Warren, G.L. (1998) Acta Cryst., D54, 905-921.
17. Schuettelkopf, A.W. and van Aalten, D.M.F. (2004) Acta Cryst., D60, 1355-1363.
18. Jones, T.A., Zou, J.Y., Cowan, S.W. and Kjeldgaard, M. (1991) Acta Cryst., A47, 110-119.