Cruentaren A, a highly cytotoxic benzolactone from Myxobacteria is a novel selective inhibitor of mitochondrial F1-ATPases

FEBS Letters

Volumn 581, Issue 18, 2007, Pages 3523-3527

  Kunze, Brigitte ^a   Sasse, Florenz ^a   Wieczorek, Helmut ^b   Huss, Markus ^b  

^a HELMHOLTZ CENTRE FOR INFECTION RESEARCH   (Germany)

^b UNIVERSITY OF OSNABRÜCK   (Germany)

Author keywords

Benzolactone class; Cruentaren; Cytotoxic activity; Mitochondrial F1 ATPase inhibitor; Myxobacteria

Indexed keywords

ADENOSINE TRIPHOSPHATASE; ADENOSINE TRIPHOSPHATASE INHIBITOR; ANTIFUNGAL AGENT; APICULAREN; CRUENTAREN A; LACTONE DERIVATIVE; UNCLASSIFIED DRUG;

APOPTOSIS; ARTICLE; BINDING SITE; CANCER; CANCER CELL CULTURE; CANCER INHIBITION; CATALYSIS; CELL CYCLE G0 PHASE; CELL CYCLE G1 PHASE; CYTOTOXICITY; DRUG ACTIVITY; HUMAN; HUMAN CELL; IC 50; MITOCHONDRION; MYXOCOCCALES; PATHOPHYSIOLOGY; PRIORITY JOURNAL; PROTEIN DOMAIN;

ANIMALS; BENZENE; BICYCLO COMPOUNDS, HETEROCYCLIC; CATTLE; CELL LINE; CELL PROLIFERATION; ENZYME INHIBITORS; HEART; HUMANS; KINETICS; MACROLIDES; MITOCHONDRIAL PROTON-TRANSLOCATING ATPASES; MOLECULAR STRUCTURE; MYOCARDIUM; MYXOCOCCALES; SOLUBILITY;

MYXOCOCCALES;

EID: 34447280880     PISSN: 00145793     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.febslet.2007.06.069     Document Type: Article

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