Elimination of methyl methanesulfonate (MMS)-induced micronuclei (MNS) under mild hyperthermia via p53-dependent pathway in human lymphoid cells

Research Communications in Molecular Pathology and Pharmacology

Volumn 115-116, Issue , 2004, Pages 175-183

  Hwa, Jin Jung ^a   Jee, Na Hwang ^a   Seo, Young R ^a  

^a Kyung Hee University Hospital   (South Korea)

Author keywords

Apoptosis; Carcinogenic DNA damage; Genotoxic stress; Micronuclei (MN); Mild hyperthermia; p53

Indexed keywords

MESYLIC ACID METHYL ESTER; PROTEIN P53; MUTAGENIC AGENT;

ARTICLE; CANCER RISK; CARCINOGENESIS; CHROMOSOMAL INSTABILITY; CONTROLLED STUDY; DNA DAMAGE; GENOTOXICITY; HUMAN; HUMAN CELL; HYPERTHERMIC THERAPY; LYMPHOID CELL; MICRONUCLEUS; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN FUNCTION; CELL NUCLEUS; CULTURE TECHNIQUE; ENZYME LINKED IMMUNOSORBENT ASSAY; GENETICS; LYMPHOCYTE; METABOLISM; MICRONUCLEUS TEST; TUMOR CELL LINE;

CELL CULTURE TECHNIQUES; CELL LINE, TUMOR; CELL NUCLEUS; ENZYME-LINKED IMMUNOSORBENT ASSAY; HUMANS; HYPERTHERMIA, INDUCED; LYMPHOCYTES; METHYL METHANESULFONATE; MICRONUCLEUS TESTS; MUTAGENS; TUMOR SUPPRESSOR PROTEIN P53;

EID: 34447275679     PISSN: 10780297     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (14)

1. Cummings, M. (1995). Increased c-fos expression associated with hyperthermia-induced apoptosis of a Burkitt lymphoma cell line. Int. J. Radiat. Biol. 68: 687-692.
2. Harmon, B.V., Corder, A. M., Collins, R. J., Gobe, G. C., Allen, J., Allan, D. J., and Kerr, J. F. R. (1990). Cell death induced in a murine mastocytoma by 42-47°C heating in vitro: Evidence that the form of death changes from apoptosis to necrosis above a critical heat. Int. J. Rad. Biol. 58: 845-858.
3. Honma, M., Tadokoro, S., Sakamoto, H., Tanabe, H., Sugimoto, M., Furuichi, Y., Satoh, T., Sofuni, T., Goto, M., and Hayashi, M. (2002). Chromosomal instability in B-lymphoblastoid cell lines from Werner and Bloom syndrome patients. Mutat. Res. 520: 15-24.
4. Lindquist, S., and Craig, E. A. (1988). The heat-shock proteins. Annu. Rev. Genet. 22: 631-677.
5. Lu, X., and Lane, D. P. (1993). Differential induction of transcriptionally active p53 following UV or ionizing irradiation: defects in chromosome instability syndromes? Cell 75: 765-778.
6. Matsuoka, A., Matsuura, K., Sakamoto, H., Hayashi, M., and Sofuni, T. (1999). A proposal for a simple way to distinguish aneugens form clastogens in the vitro micronucleus test. Mutagenesis 14: 385-389.
7. Nath, J., and Krishna, G. (1998). Safety screening of drugs in cancer therapy. Acta. Haematol. 99: 138-147.
8. Nicolaou, K. C., Stabila, P., Esmaeli-Azad, B., Wrasidlo, W., and Hiatt, A. (1993). Cell-specific regulation of apoptosis by designed enediynes. Proc. Natl. Acad. Sci. USA. 90: 3142-3146.
9. Ohnishi, T., Wang, X., Ohnishi, K., Matsumoto, H., and Takahashi, A. (1996). p53-dependent induction of WAF1 by heat treatment in human glioblastoma cells. J. Biol. Chem. 271: 14510-14513.
10. Pluquet, O., and Hainaut, P. (2001). Genotoxic and non-genotoxic pathways of p53 induction. Cancer Letters. 174: 1-15.
11. Seo, Y. R., Smith, M. L., Han, S. S., Fairbairn, D. W., O'Neill, K. L., and Ryu, J. C. (1999). Mild hyperthermia-induced apoptosis is dependent on p53 in human lymphoid cells. Res. Commun. Mol. Pathol. Pharmacol. 104: 285-292.
12. Takano, Y. S., Harmon, B.V., and Kerr, J.F.R. (1991). Apoptosis induced by mild hyperthermia in human and murine tumor cell lines: a study using electron microscopy and DNA gel electrophoresis. J. Pathol. 163: 329-336.
13. Weller, M. (1998). Predicting response to cancer chemotherapy: the role of p53. Cell Tissue Res. 292: 435-445.
14. Yonezawa, M., Otsuka, T., Matsui, N., Tsuji, H., Kato, K. H., Moriyama, A., and Kato, T. (1996). Hyperthermia induces apoptosis in malignant fibrous histiocytoma cells in vitro. Int. J. Cancer 66: 347-351.