Age-dependent changes in the hippocampal antioxidant ability of EL mice

Neuroscience Research

Volumn 58, Issue 3, 2007, Pages 336-338

  Takaki, Mayuko ^a   Ueda, Yuto ^b   Doi, Taku ^b   Nagatomo, Keiko ^b   Murashima, Yoshiya L ^c   Nakajima, Akira ^b   Kannan, Hiroshi ^a  

^a UNIVERSITY OF MIYAZAKI   (Japan)

^b UNIVERSITY OF MIYAZAKI   (Japan)

^c TOKYO METROPOLITAN INSTITUTE OF MEDICAL SCIENCE   (Japan)

Author keywords

Antioxidant ability; EL mice; Epilepsy; ESR; Nitroxide radical; Redox

Indexed keywords

3 METHOXYCARBONYL 2,2,5,5 TETRAMETHYLPYRROLIDINE 1 OXYL; ANTIOXIDANT; CARBONYL DERIVATIVE; NITROXIDE; PYRROLIDINE DERIVATIVE; RADICAL; UNCLASSIFIED DRUG;

AGE; ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIOXIDANT ACTIVITY; ARTICLE; CONTROLLED STUDY; ELECTRON SPIN RESONANCE; EPILEPTOGENESIS; HALF LIFE TIME; HIPPOCAMPUS; IN VIVO STUDY; LIMBIC SYSTEM; MICRODIALYSIS; MOUSE; NONHUMAN; OXIDATION REDUCTION STATE; OXIDATIVE STRESS; PRIORITY JOURNAL; SEIZURE;

AGING; ANIMALS; ANTIOXIDANTS; CYCLIC N-OXIDES; EPILEPSY; HALF-LIFE; HIPPOCAMPUS; MICE; MICE, NEUROLOGIC MUTANTS; PYRROLIDINES;

EID: 34447271440     PISSN: 01680102     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.neures.2007.03.013     Document Type: Article

References (17)

1. Dal-Pizzol F., Klamt F., Vianna M.M., Schroder N., Quevedo J., Benfato M.S., Moreira J.C., and Walz R. Lipid peroxidation in hippocampus early and late after status epilepticus induced by pilocarpine or kainic acid in Wistar rats. Neurosci. Lett. 291 (2000) 179-182
2. Franklin K.B.J., and Paxinos G. The Mouse Brain in Stereotaxic Coordinates (1997), Academic Press
3. Ishida N., Kasamo K., Nakamoto Y., and Suzuki J. Epileptic seizure of El mouse initiates at the parietal cortex: depth EEG observation in freely moving condition using buffer amplifier. Brain Res. 608 (1993) 52-57
4. King Jr. J.T., and LaMotte C.C. EL mouse as a model of focal epilepsy: a review. Epilepsia 30 (1989) 257-265
5. Lewerenz J., Klein M., and Methner A. Cooperative action of glutamate transporters and cystine/glutamate antiporter system Xc - protects from oxidative glutamate toxicity. J. Neurochem. 98 (2006) 916-925
6. Michiels C., Raes M., Toussaint O., and Remacle J. Importance of Se-glutathione peroxidase, catalase, and Cu/Zn-SOD for cell survival against oxidative stress. Free Radic. Biol. Med. 17 (1994) 235-248
7. Murashima Y.L., Kasamo K., and Suzuki J. Antiepileptic effects of allopurinol on EL mice are associated with changes in SOD isoenzyme activities. Epilepsy Res. 32 (1998) 254-265
8. Murashima Y.L., Kassamo K., and Suzuki J. Developmental and seizure-related regional differences in immediate early gene expression and GABAergic abnormalities in the brain of EL mice. Epilepsy Res. 26 (1996) 3-14
9. Murashima Y.L., Suzuki J., and Yoshii M. Developmental program of epileptogenesis in the brain of EL mice. Epilepsia 46 Suppl. 5 (2005) 10-16
10. Seyfried T.N., Todorova M.T., and Poderycki M.J. Experimental models of multifactorial epilepsies: the EL mouse and mice susceptible to audiogenic seizures. Adv. Neurol. 79 (1999) 279-290
11. Suzuki J., Nakamoto Y., and Shinkawa Y. Local cerebral glucose utilization in epileptic seizures of the mutant EL mouse. Brain Res. 266 (1983) 359-363
12. Todorova M.T., Burwell T.J., and Seyfried T.N. Environmental risk factors for multifactorial epilepsy in EL mice. Epilepsia 40 (1999) 1697-1707
13. Trotti D., Rizzini B.L., Rossi D., Haugeto O., Racagni G., Danbolt N.C., and Volterra A. Neuronal and glial glutamate transporters possess an SH-based redox regulatory mechanism. Eur. J. Neurosci. 9 (1997) 1236-1243
14. Ueda Y., Yokoyama H., Niwa R., Konaka R., Ohya-Nishiguchi H., and Kamada H. Generation of lipid radicals in the hippocampal extracellular space during kainic acid-induced seizures in rats. Epilepsy Res. 26 (1997) 329-333
15. Ueda Y., Yokoyama H., Ohya-Nishiguchi H., and Kamada H. ESR spectroscopy for analysis of hippocampal elimination of a nitroxide radical during kainic acid-induced seizure in rats. Magn. Reson. Med. 40 (1998) 491-493
16. Ueda Y., Yokoyama H., Tokumaru J., Doi T., and Nakajima A. Kinetics of extracellular nitroxide radical and glutamate levels in the hippocampus of conscious rats: cautionary note to the application of nitroxide radical on clinical arena. Neurochem. Res. 29 (2004) 1695-1701
17. Waterfall A.H., Singh G., Fry J.R., and Marsden C.A. Detection of the lipid peroxidation product malonaldehyde in rat brain in vivo. Neurosci. Lett. 200 (1995) 69-72