Downregulation of urokinase plasminogen activator receptor expression inhibits Erk signalling with concomitant suppression of invasiveness due to loss of uPAR-β1 integrin complex in colon cancer cells

British Journal of Cancer

Volumn 89, Issue 2, 2003, Pages 374-384

  Ahmed, N ^a,c   Oliva, K ^a   Wang, Y ^b   Quinn, M ^a   Rice, G ^a  

^a UNIVERSITY OF MELBOURNE   (Australia)

^b UNIVERSITY OF NEW SOUTH WALES   (Australia)

^c ROYAL WOMEN'S HOSPITAL   (Australia)

Author keywords

1 integrin; Colon cancer; Plasminogen activation and metastasis; Urokinase plasminogen activator receptor

Indexed keywords

BETA1 INTEGRIN; GELATINASE A; GELATINASE B; MATRIX METALLOPROTEINASE; MITOGEN ACTIVATED PROTEIN KINASE; PLASMIN; PROTEINASE ACTIVATED RECEPTOR 1; UROKINASE RECEPTOR;

ARTICLE; CANCER CELL CULTURE; CANCER INVASION; CELL SURFACE; CONTROLLED STUDY; ENZYME ACTIVATION; ENZYME ACTIVITY; HUMAN; HUMAN CELL; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN SECRETION; RECEPTOR DOWN REGULATION; SIGNAL TRANSDUCTION;

ANTIGENS, CD29; COLONIC NEOPLASMS; DOWN-REGULATION; HUMANS; MANNOSE-BINDING LECTINS; MEMBRANE GLYCOPROTEINS; MITOGEN-ACTIVATED PROTEIN KINASES; NEOPLASM INVASIVENESS; NEOPLASM METASTASIS; RECEPTORS, CELL SURFACE; SIGNAL TRANSDUCTION; TRANSFECTION; TUMOR CELLS, CULTURED;

EID: 0042121063     PISSN: 00070920     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.bjc.6601098     Document Type: Article

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