Novel selective PPARδ agonists: Optimization of activity by modification of alkynylallylic moiety

Bioorganic and Medicinal Chemistry Letters

Volumn 17, Issue 15, 2007, Pages 4144-4149

  Havranek, Miroslav ^a   Sauerberg, Per ^b   Mogensen, John P ^b   Kratina, Pavel ^a   Jeppesen, Claus B ^b   Pettersson, Ingrid ^b   Pihera, Pavel ^a  

^a RE and D VÚFB s r o   (Czech Republic)

^b NOVO NORDISK A S   (Denmark)

Author keywords

Hydroalumination; Nuclear receptor; Peroxisome proliferator activated receptor ; PPAR agonists; Substituted allyl alcohols

Indexed keywords

PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA AGONIST; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR DELTA;

ARTICLE; CHEMICAL STRUCTURE; CROSS COUPLING REACTION; DRUG POTENTIATION;

MODELS, MOLECULAR; MOLECULAR STRUCTURE; PPAR DELTA;

EID: 34447122589     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmcl.2007.05.051     Document Type: Article

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