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Volumn 26, Issue 8, 2007, Pages 1306-1311

Effects of hyaluronan on nitric oxide levels and superoxide dismutase activities in synovial fluid in knee osteoarthritis

Author keywords

Hyaluronan; Knee osteoarthritis; Nitric oxide; Superoxide dismutase; Synovial fluid

Indexed keywords

ANTIOXIDANT; COPPER ZINC SUPEROXIDE DISMUTASE; HYALURONIC ACID; MANGANESE SUPEROXIDE DISMUTASE; NITRIC OXIDE; SUPEROXIDE DISMUTASE;

EID: 34447117501     PISSN: 07703198     EISSN: None     Source Type: Journal    
DOI: 10.1007/s10067-006-0504-y     Document Type: Article
Times cited : (27)

References (59)
  • 1
    • 27744597628 scopus 로고    scopus 로고
    • Extracellular superoxide dismutase and oxidant damage in osteoarthritis
    • Regan E, Flannelly J, Bowler R et al (2005) Extracellular superoxide dismutase and oxidant damage in osteoarthritis. Arthritis Rheum 52:3479-3491
    • (2005) Arthritis Rheum , vol.52 , pp. 3479-3491
    • Regan, E.1    Flannelly, J.2    Bowler, R.3
  • 2
    • 0035076295 scopus 로고    scopus 로고
    • Articular cartilage and changes in arthritis. An introduction: Cell biology of osteoarthritis
    • Sandell LJ, Aigner T (2001) Articular cartilage and changes in arthritis. An introduction: Cell biology of osteoarthritis. Arthritis Res 3:107-113
    • (2001) Arthritis Res , vol.3 , pp. 107-113
    • Sandell, L.J.1    Aigner, T.2
  • 3
    • 0031837375 scopus 로고    scopus 로고
    • Chondrocyte apoptosis and nitric oxide production during experimentally induced osteoarthritis
    • Hashimoto S, Takahashi K, Amiel D et al (1998) Chondrocyte apoptosis and nitric oxide production during experimentally induced osteoarthritis. Arthritis Rheum 41:1266-1274
    • (1998) Arthritis Rheum , vol.41 , pp. 1266-1274
    • Hashimoto, S.1    Takahashi, K.2    Amiel, D.3
  • 4
    • 0031886742 scopus 로고    scopus 로고
    • Osteoarthritis chondrocytes die by apoptosis. A possible pathway for osteoarthritis pathology
    • Blanco FJ, Guitian R, Vazquez-Martul E et al (1998) Osteoarthritis chondrocytes die by apoptosis. A possible pathway for osteoarthritis pathology. Arthritis Rheum 41:284-289
    • (1998) Arthritis Rheum , vol.41 , pp. 284-289
    • Blanco, F.J.1    Guitian, R.2    Vazquez-Martul, E.3
  • 5
    • 0034762985 scopus 로고    scopus 로고
    • Proinflammatory cytokines regulate the gene expression of hyaluronic acid synthetase in cultured rabbit synovial membrane cells
    • Tanimoto K, Ohno S, Fujimoto K et al (2001) Proinflammatory cytokines regulate the gene expression of hyaluronic acid synthetase in cultured rabbit synovial membrane cells. Connect Tissue Res 42:187-195
    • (2001) Connect Tissue Res , vol.42 , pp. 187-195
    • Tanimoto, K.1    Ohno, S.2    Fujimoto, K.3
  • 6
    • 0031658981 scopus 로고    scopus 로고
    • Linkage of chondrocyte apoptosis and cartilage degradation in human osteoarthritis
    • Hashimoto S, Ochs RL, Komiya S, Lotz M (1998) Linkage of chondrocyte apoptosis and cartilage degradation in human osteoarthritis. Arthritis Rheum 41:1632-1638
    • (1998) Arthritis Rheum , vol.41 , pp. 1632-1638
    • Hashimoto, S.1    Ochs, R.L.2    Komiya, S.3    Lotz, M.4
  • 8
    • 0034792290 scopus 로고    scopus 로고
    • Cytokines in cartilage injury and repair
    • Lotz M (2001) Cytokines in cartilage injury and repair. Clin Orthop Relat Res Suppl 391:108-115
    • (2001) Clin Orthop Relat Res Suppl , vol.391 , pp. 108-115
    • Lotz, M.1
  • 9
    • 0034971296 scopus 로고    scopus 로고
    • Osteoarthritis, an inflammatory disease: Potential implication for the selection of new therapeutic targets
    • Pelletier JP, Martel-Pelletier J, Abramson SB (2001) Osteoarthritis, an inflammatory disease: Potential implication for the selection of new therapeutic targets. Arthritis Rheum 44:1237-1247
    • (2001) Arthritis Rheum , vol.44 , pp. 1237-1247
    • Pelletier, J.P.1    Martel-Pelletier, J.2    Abramson, S.B.3
  • 10
    • 0033569188 scopus 로고    scopus 로고
    • An introduction to the pathophysiology of osteoarthritis
    • Poole AR (1999) An introduction to the pathophysiology of osteoarthritis. Front Biosci 4:662-670
    • (1999) Front Biosci , vol.4 , pp. 662-670
    • Poole, A.R.1
  • 11
    • 0034840936 scopus 로고    scopus 로고
    • The role of ADAM-TS4 (aggrecanase-1) and ADAM-TS5 (aggrecanase-2) in a model of cartilage degradation
    • Tortorella MD, Malfait AM, Deccico C, Arner E (2001) The role of ADAM-TS4 (aggrecanase-1) and ADAM-TS5 (aggrecanase-2) in a model of cartilage degradation. Osteoarthritis Cartilage 9:539-552
    • (2001) Osteoarthritis Cartilage , vol.9 , pp. 539-552
    • Tortorella, M.D.1    Malfait, A.M.2    Deccico, C.3    Arner, E.4
  • 12
    • 0031864605 scopus 로고    scopus 로고
    • Reduced progression of experimental osteoarthritis in vivo by selective inhibition of inducible nitric oxide synthase
    • Pelletier JP, Jovanovic D, Fernandes JC et al (1998) Reduced progression of experimental osteoarthritis in vivo by selective inhibition of inducible nitric oxide synthase. Arthritis Rheum 41:1275-1286
    • (1998) Arthritis Rheum , vol.41 , pp. 1275-1286
    • Pelletier, J.P.1    Jovanovic, D.2    Fernandes, J.C.3
  • 14
    • 0031833414 scopus 로고    scopus 로고
    • The role of nitric oxide in articular cartilage breakdown in osteoarthritis
    • Amin AR, Abramson SB (1998) The role of nitric oxide in articular cartilage breakdown in osteoarthritis. Curr Opin Rheumatol 10:263-268
    • (1998) Curr Opin Rheumatol , vol.10 , pp. 263-268
    • Amin, A.R.1    Abramson, S.B.2
  • 15
    • 0031809547 scopus 로고    scopus 로고
    • The role of nitric oxide in inflammation and immunity
    • Clancy RM, Amin AR, Abramson SB (1998) The role of nitric oxide in inflammation and immunity. Arthritis Rheum 41:1141-1151
    • (1998) Arthritis Rheum , vol.41 , pp. 1141-1151
    • Clancy, R.M.1    Amin, A.R.2    Abramson, S.B.3
  • 16
    • 0031904069 scopus 로고    scopus 로고
    • Nitric oxide - Friend or foe in arthritis?
    • St Clair EW (1998) Nitric oxide - friend or foe in arthritis? J Rheumatol 25:1451-1453
    • (1998) J Rheumatol , vol.25 , pp. 1451-1453
    • St Clair, E.W.1
  • 17
    • 0029986420 scopus 로고    scopus 로고
    • The increased synthesis of inducible nitric oxide inhibits IL-1ra synthesis by human articular chondrocytes: Possible role in osteoarthritic cartilage degradation
    • Pelletier JP, Mineau F, Ranger P et al (1996) The increased synthesis of inducible nitric oxide inhibits IL-1ra synthesis by human articular chondrocytes: Possible role in osteoarthritic cartilage degradation. Osteoarthritis Cartilage 4:77-84
    • (1996) Osteoarthritis Cartilage , vol.4 , pp. 77-84
    • Pelletier, J.P.1    Mineau, F.2    Ranger, P.3
  • 18
    • 0036793531 scopus 로고    scopus 로고
    • Oxygen radicals and nitric oxide levels in chondral or meniscal lesions or both
    • Haklar U, Yuksel M, Velioglu A et al (2002) Oxygen radicals and nitric oxide levels in chondral or meniscal lesions or both. Clin Orthop Relat Res 403:135-142
    • (2002) Clin Orthop Relat Res , vol.403 , pp. 135-142
    • Haklar, U.1    Yuksel, M.2    Velioglu, A.3
  • 19
    • 18744384078 scopus 로고    scopus 로고
    • In vivo effect of celecoxib and tenoxicam on oxidant/anti-oxidant status of patients with knee osteoarthritis
    • Ozgocmen S, Ardicoglu O, Erdogan H et al (2005) In vivo effect of celecoxib and tenoxicam on oxidant/anti-oxidant status of patients with knee osteoarthritis. Ann Clin Lab Sci 35:137-143
    • (2005) Ann Clin Lab Sci , vol.35 , pp. 137-143
    • Ozgocmen, S.1    Ardicoglu, O.2    Erdogan, H.3
  • 20
    • 10244253892 scopus 로고    scopus 로고
    • Production of nitric oxide in the synovial membrane of rheumatoid and osteoarthritis patients
    • McInnes IB, Leung BP, Field M et al (1996) Production of nitric oxide in the synovial membrane of rheumatoid and osteoarthritis patients. J Exp Med 184:1519-1524
    • (1996) J Exp Med , vol.184 , pp. 1519-1524
    • McInnes, I.B.1    Leung, B.P.2    Field, M.3
  • 21
    • 2342533252 scopus 로고    scopus 로고
    • Synovial fluid nitric oxide levels in patients with knee osteoarthritis
    • Karan A, Karan MA, Vural P et al (2003) Synovial fluid nitric oxide levels in patients with knee osteoarthritis. Clin Rheumatol 22:397-399
    • (2003) Clin Rheumatol , vol.22 , pp. 397-399
    • Karan, A.1    Karan, M.A.2    Vural, P.3
  • 22
    • 0033036389 scopus 로고    scopus 로고
    • The role of nitric oxide in articular cartilage damage
    • Lotz M (1999) The role of nitric oxide in articular cartilage damage. Rheum Dis Clin North Am 25:269-282
    • (1999) Rheum Dis Clin North Am , vol.25 , pp. 269-282
    • Lotz, M.1
  • 23
    • 0033065891 scopus 로고    scopus 로고
    • Aggrecan degradation in chondrocytes is mediated by reactive oxygen species and protected by antioxidants
    • Tiku ML, Gupta S, Deshmukh DR (1999) Aggrecan degradation in chondrocytes is mediated by reactive oxygen species and protected by antioxidants. Free Radic Res 30:395-405
    • (1999) Free Radic Res , vol.30 , pp. 395-405
    • Tiku, M.L.1    Gupta, S.2    Deshmukh, D.R.3
  • 25
    • 0038300845 scopus 로고    scopus 로고
    • Intra-articular hyaluronan (hyaluronic acid) and hylans for the treatment of osteoarthritis: Mechanisms of action
    • Moreland LW (2003) Intra-articular hyaluronan (hyaluronic acid) and hylans for the treatment of osteoarthritis: Mechanisms of action. Arthritis Res Ther 5:54-67
    • (2003) Arthritis Res Ther , vol.5 , pp. 54-67
    • Moreland, L.W.1
  • 26
    • 0022465236 scopus 로고
    • Development of criteria for the classification and reporting of osteoarthritis. Classification of osteoarthritis of the knee. Diagnostic and Therapeutic Criteria Committee of the American Rheumatism Association
    • Altman R, Asch E, Bloch D et al (1986) Development of criteria for the classification and reporting of osteoarthritis. Classification of osteoarthritis of the knee. Diagnostic and Therapeutic Criteria Committee of the American Rheumatism Association. Arthritis Rheum 29:1039-1049
    • (1986) Arthritis Rheum , vol.29 , pp. 1039-1049
    • Altman, R.1    Asch, E.2    Bloch, D.3
  • 27
    • 62949246527 scopus 로고
    • Radiological assessment of osteo-arthrosis
    • Kellgren JH, Lawrence JS (1957) Radiological assessment of osteo-arthrosis. Ann Rheum Dis 16:494-502
    • (1957) Ann Rheum Dis , vol.16 , pp. 494-502
    • Kellgren, J.H.1    Lawrence, J.S.2
  • 28
    • 0025125066 scopus 로고
    • Determination of inorganic nitrate in serum and urine by a kinetic cadmium-reduction method
    • Cortas NK, Wakid NW (1990) Determination of inorganic nitrate in serum and urine by a kinetic cadmium-reduction method. Clin Chem 36:1440-1443
    • (1990) Clin Chem , vol.36 , pp. 1440-1443
    • Cortas, N.K.1    Wakid, N.W.2
  • 29
    • 0023952554 scopus 로고
    • A simple method for clinical assay of superoxide dismutase
    • Sun Y, Oberley LW, Li Y (1988) A simple method for clinical assay of superoxide dismutase. Clin Chem 34:497-500
    • (1988) Clin Chem , vol.34 , pp. 497-500
    • Sun, Y.1    Oberley, L.W.2    Li, Y.3
  • 30
    • 0036237812 scopus 로고    scopus 로고
    • Effects of shear stress on nitric oxide and matrix protein gene expression in human osteoarthritic chondrocytes in vitro
    • Lee MS, Trindade MC, Ikenoue T et al (2002) Effects of shear stress on nitric oxide and matrix protein gene expression in human osteoarthritic chondrocytes in vitro. J Orthop Res 20:556-561
    • (2002) J Orthop Res , vol.20 , pp. 556-561
    • Lee, M.S.1    Trindade, M.C.2    Ikenoue, T.3
  • 32
    • 3242706033 scopus 로고    scopus 로고
    • The effects of intraarticularly injected sodium hyaluronate on levels of intact aggrecan and nitric oxide in the joint fluid of patients with knee osteoarthritis
    • Kobayashi K, Matsuzaka S, Yoshida Y et al (2004) The effects of intraarticularly injected sodium hyaluronate on levels of intact aggrecan and nitric oxide in the joint fluid of patients with knee osteoarthritis. Osteoarthritis Cartilage 12:536-542
    • (2004) Osteoarthritis Cartilage , vol.12 , pp. 536-542
    • Kobayashi, K.1    Matsuzaka, S.2    Yoshida, Y.3
  • 33
    • 0141504018 scopus 로고    scopus 로고
    • The role of reactive oxygen species in homeostasis and degradation of cartilage
    • Henrotin YE, Bruckner P, Pujol JP (2003) The role of reactive oxygen species in homeostasis and degradation of cartilage. Osteoarthritis Cartilage 11:747-755
    • (2003) Osteoarthritis Cartilage , vol.11 , pp. 747-755
    • Henrotin, Y.E.1    Bruckner, P.2    Pujol, J.P.3
  • 34
    • 0028872942 scopus 로고
    • Nitric oxide activates metalloprotease enzymes in articular cartilage
    • Murrell GA, Jang D, Williams RJ (1995) Nitric oxide activates metalloprotease enzymes in articular cartilage. Biochem Biophys Res Commun 206:15-21
    • (1995) Biochem Biophys Res Commun , vol.206 , pp. 15-21
    • Murrell, G.A.1    Jang, D.2    Williams, R.J.3
  • 35
    • 0035008314 scopus 로고    scopus 로고
    • Activation of stress-activated protein kinase in osteoarthritic cartilage: Evidence for nitric oxide dependence
    • Clancy R, Rediske J, Koehne C et al (2001) Activation of stress-activated protein kinase in osteoarthritic cartilage: Evidence for nitric oxide dependence. Osteoarthritis Cartilage 9:294-299
    • (2001) Osteoarthritis Cartilage , vol.9 , pp. 294-299
    • Clancy, R.1    Rediske, J.2    Koehne, C.3
  • 36
    • 0029043151 scopus 로고
    • IL-1-induced nitric oxide inhibits chondrocyte proliferation via PGE2
    • Blanco FJ, Lotz M (1995) IL-1-induced nitric oxide inhibits chondrocyte proliferation via PGE2. Exp Cell Res 218:319-325
    • (1995) Exp Cell Res , vol.218 , pp. 319-325
    • Blanco, F.J.1    Lotz, M.2
  • 37
    • 0034665322 scopus 로고    scopus 로고
    • The induction of cell death in human osteoarthritis chondrocytes by nitric oxide is related to the production of prostaglandin E2 via the induction of cyclooxygenase-2
    • Notoya K, Jovanovic DV, Reboul P et al (2000) The induction of cell death in human osteoarthritis chondrocytes by nitric oxide is related to the production of prostaglandin E2 via the induction of cyclooxygenase-2. J Immunol 165:3402-3410
    • (2000) J Immunol , vol.165 , pp. 3402-3410
    • Notoya, K.1    Jovanovic, D.V.2    Reboul, P.3
  • 39
    • 0035677247 scopus 로고    scopus 로고
    • Amelioration of joint disease in a rat model of collagen-induced arthritis by M40403, a superoxide dismutase mimetic
    • Salvemini D, Mazzon E, Dugo L et al (2001) Amelioration of joint disease in a rat model of collagen-induced arthritis by M40403, a superoxide dismutase mimetic. Arthritis Rheum 44:2909-2921
    • (2001) Arthritis Rheum , vol.44 , pp. 2909-2921
    • Salvemini, D.1    Mazzon, E.2    Dugo, L.3
  • 40
    • 0019974866 scopus 로고
    • Serum copper and erythrocyte superoxide dismutase in rheumatoid arthritis
    • Banford JC, Brown DH, Hazelton RA et al (1982) Serum copper and erythrocyte superoxide dismutase in rheumatoid arthritis. Ann Rheum Dis 41:458-462
    • (1982) Ann Rheum Dis , vol.41 , pp. 458-462
    • Banford, J.C.1    Brown, D.H.2    Hazelton, R.A.3
  • 41
    • 0020082109 scopus 로고
    • A remarkable increase of superoxide dismutase activity in synovial fluid of patients with rheumatoid arthritis
    • Igari T, Kaneda H, Horiuchi S, Ono S (1982) A remarkable increase of superoxide dismutase activity in synovial fluid of patients with rheumatoid arthritis. Clin Orthop Relat Res 162:282-287
    • (1982) Clin Orthop Relat Res , vol.162 , pp. 282-287
    • Igari, T.1    Kaneda, H.2    Horiuchi, S.3    Ono, S.4
  • 42
    • 0033866512 scopus 로고    scopus 로고
    • Oxidant/antioxidant status of the erythrocytes from patients with rheumatoid arthritis
    • Cimen MY, Cimen OB, Kacmaz M et al (2000) Oxidant/antioxidant status of the erythrocytes from patients with rheumatoid arthritis. Clin Rheumatol 19:275-277
    • (2000) Clin Rheumatol , vol.19 , pp. 275-277
    • Cimen, M.Y.1    Cimen, O.B.2    Kacmaz, M.3
  • 43
    • 0030158925 scopus 로고    scopus 로고
    • Superoxide dismutase activity in arthropathy: Its role and measurement in the joints
    • Sumii H, Inoue H, Onoue J et al (1996) Superoxide dismutase activity in arthropathy: Its role and measurement in the joints. Hiroshima J Med Sci 45:51-55
    • (1996) Hiroshima J Med Sci , vol.45 , pp. 51-55
    • Sumii, H.1    Inoue, H.2    Onoue, J.3
  • 44
    • 0030481032 scopus 로고    scopus 로고
    • Serum copper/zinc superoxide dismutase levels in patients with rheumatoid arthritis
    • Mazzetti I, Grigolo B, Borzi RM et al (1996) Serum copper/zinc superoxide dismutase levels in patients with rheumatoid arthritis. Int J Clin Lab Res 26:245-249
    • (1996) Int J Clin Lab Res , vol.26 , pp. 245-249
    • Mazzetti, I.1    Grigolo, B.2    Borzi, R.M.3
  • 45
    • 0027292127 scopus 로고
    • Histomorphological studies on the effect of recombinant human superoxide dismutase in biochemically induced osteoarthritis
    • Hoedt-Schmidt S, Schneider B, Kalbhen DA (1993) Histomorphological studies on the effect of recombinant human superoxide dismutase in biochemically induced osteoarthritis. Pharmacology 47:252-260
    • (1993) Pharmacology , vol.47 , pp. 252-260
    • Hoedt-Schmidt, S.1    Schneider, B.2    Kalbhen, D.A.3
  • 46
    • 0023856199 scopus 로고
    • Antioxidant activity of synovial fluid, hyaluronic acid, and two subcomponents of hyaluronic acid. Synovial fluid scavenging effect is enhanced in rheumatoid arthritis patients
    • Sato H, Takahashi T, Ide H et al (1988) Antioxidant activity of synovial fluid, hyaluronic acid, and two subcomponents of hyaluronic acid. Synovial fluid scavenging effect is enhanced in rheumatoid arthritis patients. Arthritis Rheum 31:63-71
    • (1988) Arthritis Rheum , vol.31 , pp. 63-71
    • Sato, H.1    Takahashi, T.2    Ide, H.3
  • 47
    • 0035008315 scopus 로고    scopus 로고
    • Sodium hyaluronate inhibits interleukin-1-evoked reactive oxygen species of bovine articular chondrocytes
    • Fukuda K, Oh M, Asada S et al (2001) Sodium hyaluronate inhibits interleukin-1-evoked reactive oxygen species of bovine articular chondrocytes. Osteoarthritis Cartilage 9:390-392
    • (2001) Osteoarthritis Cartilage , vol.9 , pp. 390-392
    • Fukuda, K.1    Oh, M.2    Asada, S.3
  • 48
    • 0030943154 scopus 로고    scopus 로고
    • Hyaluronic acid inhibits interleukin-1-induced superoxide anion in bovine chondrocytes
    • Fukuda K, Takayama M, Ueno M et al (1997) Hyaluronic acid inhibits interleukin-1-induced superoxide anion in bovine chondrocytes. Inflamm Res 46:114-117
    • (1997) Inflamm Res , vol.46 , pp. 114-117
    • Fukuda, K.1    Takayama, M.2    Ueno, M.3
  • 49
    • 0029018699 scopus 로고
    • Oxygen-derived free radical (ODFR) action on hyaluronan (HA), on two HA ester derivatives, and on the metabolism of articular chondrocytes
    • Kvam BJ, Fragonas E, Degrassi A et al (1995) Oxygen-derived free radical (ODFR) action on hyaluronan (HA), on two HA ester derivatives, and on the metabolism of articular chondrocytes. Exp Cell Res 218:79-86
    • (1995) Exp Cell Res , vol.218 , pp. 79-86
    • Kvam, B.J.1    Fragonas, E.2    Degrassi, A.3
  • 50
    • 0028139442 scopus 로고
    • Hyaluronan-mediated protective effect against cell damage caused by enzymatically produced hydroxyl (OH) radicals is dependent on hyaluronan molecular mass Cell
    • Presti D, Scott JE (1994) Hyaluronan-mediated protective effect against cell damage caused by enzymatically produced hydroxyl (OH) radicals is dependent on hyaluronan molecular mass. Cell Biochem Funct 12:281-288
    • (1994) Biochem Funct , vol.12 , pp. 281-288
    • Presti, D.1    Scott, J.E.2
  • 51
    • 0034999149 scopus 로고    scopus 로고
    • Hyaluronan suppressed nitric oxide production in the meniscus and synovium of rabbit osteoarthritis model
    • Takahashi K, Hashimoto S, Kubo T et al (2001) Hyaluronan suppressed nitric oxide production in the meniscus and synovium of rabbit osteoarthritis model. J Orthop Res 19:500-503
    • (2001) J Orthop Res , vol.19 , pp. 500-503
    • Takahashi, K.1    Hashimoto, S.2    Kubo, T.3
  • 52
    • 0036052630 scopus 로고    scopus 로고
    • The suppressive effect of hyaluronan on nitric oxide production and cell apoptosis in the central region of meniscus following partial meniscectomy
    • Kobayashi K, Mishima H, Harwood F et al (2002) The suppressive effect of hyaluronan on nitric oxide production and cell apoptosis in the central region of meniscus following partial meniscectomy. Iowa Orthop J 22:39-41
    • (2002) Iowa Orthop J , vol.22 , pp. 39-41
    • Kobayashi, K.1    Mishima, H.2    Harwood, F.3
  • 53
    • 0033910259 scopus 로고    scopus 로고
    • Effect of hyaluronan on chondrocyte apoptosis and nitric oxide production in experimentally induced osteoarthritis
    • Takahashi K, Hashimoto S, Kubo T et al (2000) Effect of hyaluronan on chondrocyte apoptosis and nitric oxide production in experimentally induced osteoarthritis. J Rheumatol 27:1713-1720
    • (2000) J Rheumatol , vol.27 , pp. 1713-1720
    • Takahashi, K.1    Hashimoto, S.2    Kubo, T.3
  • 54
    • 30344446653 scopus 로고    scopus 로고
    • Effects of different hyaluronic acid products on synovial fluid NO levels in knee osteoarthritis
    • Karatay S, Kiziltunc A, Yildirim K et al (2005) Effects of different hyaluronic acid products on synovial fluid NO levels in knee osteoarthritis. Clin Rheumatol 24:497-501
    • (2005) Clin Rheumatol , vol.24 , pp. 497-501
    • Karatay, S.1    Kiziltunc, A.2    Yildirim, K.3
  • 55
    • 0036158517 scopus 로고    scopus 로고
    • Inducible nitric oxide expression in equine articular chondrocytes: Effects of antiinflammatory compounds
    • Tung JT, Venta PJ, Caron JP (2002) Inducible nitric oxide expression in equine articular chondrocytes: Effects of antiinflammatory compounds. Osteoarthritis Cartilage 10:5-12
    • (2002) Osteoarthritis Cartilage , vol.10 , pp. 5-12
    • Tung, J.T.1    Venta, P.J.2    Caron, J.P.3
  • 56
    • 0027314084 scopus 로고
    • The kinetics of hyaluronan in normal and acutely inflamed synovial joints: Observations with experimental arthritis in sheep
    • Fraser JR, Kimpton WG, Pierscionek BK, Cahill RN (1993) The kinetics of hyaluronan in normal and acutely inflamed synovial joints: Observations with experimental arthritis in sheep. Semin Arthritis Rheum 22:9-17
    • (1993) Semin Arthritis Rheum , vol.22 , pp. 9-17
    • Fraser, J.R.1    Kimpton, W.G.2    Pierscionek, B.K.3    Cahill, R.N.4
  • 57
    • 0027435051 scopus 로고
    • Viscosupplementation: A new concept in the treatment of osteoarthritis
    • Balazs EA, Denlinger JL (1993) Viscosupplementation: A new concept in the treatment of osteoarthritis. J Rheumatol Suppl 39:3-9
    • (1993) J Rheumatol , vol.39 , Issue.SUPPL. , pp. 3-9
    • Balazs, E.A.1    Denlinger, J.L.2
  • 58
    • 0029149237 scopus 로고
    • Modulation of chondrocyte proteoglycan synthesis by endogeneously produced nitric oxide
    • Stefanovic-Racic M, Taskiran D, Georgescu HI, Evans CH (1995) Modulation of chondrocyte proteoglycan synthesis by endogeneously produced nitric oxide. Inflamm Res 44:216-217
    • (1995) Inflamm Res , vol.44 , pp. 216-217
    • Stefanovic-Racic, M.1    Taskiran, D.2    Georgescu, H.I.3    Evans, C.H.4
  • 59
    • 0028872942 scopus 로고
    • Nitric oxide activates metalloprotease enzymes in articular cartilage
    • Murrell GA, Jang D, Williams RJ (1995) Nitric oxide activates metalloprotease enzymes in articular cartilage. Biochem Biophys Res Commun 206:15-21
    • (1995) Biochem Biophys Res Commun , vol.206 , pp. 15-21
    • Murrell, G.A.1    Jang, D.2    Williams, R.J.3


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