Relationships between heart rate variability, vascular function, and adiposity in children

Clinical Autonomic Research

Volumn 17, Issue 3, 2007, Pages 165-171

  Kaufman, Christopher L ^a,b   Kaiser, Daniel R ^c   Steinberger, Julia ^c   Dengel, Donald R ^a  

^a UNIVERSITY OF MINNESOTA   (United States)

^b St Paul Heart Clinic   (United States)

^c UNIVERSITY OF MINNESOTA MEDICAL SCHOOL   (United States)

Author keywords

Cardiac autonomic function; Cardiovascular disease; Flow mediated dilation; Pediatrics

Indexed keywords

C REACTIVE PROTEIN; FAT; GLUCOSE; INSULIN; LIPID;

ADOLESCENT; ARTERY BLOOD FLOW; ARTERY DILATATION; ARTICLE; AUTONOMIC DYSFUNCTION; AUTONOMIC NERVOUS SYSTEM FUNCTION; BLOOD SAMPLING; BLOOD VESSEL FUNCTION; BODY FAT; BRACHIAL ARTERY; CARDIOVASCULAR FUNCTION; CONFOUNDING VARIABLE; CONTROLLED STUDY; CORRELATION ANALYSIS; FEMALE; FUNCTIONAL ASSESSMENT; GLUCOSE BLOOD LEVEL; HEART RATE VARIABILITY; HUMAN; INFLAMMATION; INSULIN BLOOD LEVEL; LIPID BLOOD LEVEL; MALE; NORMAL HUMAN; OBESITY; PARASYMPATHETIC NERVE; PROTEIN BLOOD LEVEL; SCHOOL CHILD; SYMPATHETIC FUNCTION; VAGUS NERVE;

ADIPOSITY; ADOLESCENT; AUTONOMIC NERVOUS SYSTEM; BLOOD PRESSURE; BRACHIAL ARTERY; CARDIOVASCULAR PHYSIOLOGY; CHILD; CONFOUNDING FACTORS (EPIDEMIOLOGY); ELECTROCARDIOGRAPHY; FEMALE; HEART RATE; HUMANS; MALE; NITROGLYCERIN; VASODILATION;

EID: 34447103609     PISSN: 09599851     EISSN: None     Source Type: Journal    
DOI: 10.1007/s10286-007-0411-6     Document Type: Article

References (30)

1. Astrup AS, Tarnow L, Rossing P, Hansen BV, Hilsted J, Parving HH (2006) Cardiac autonomic neuropathy predicts cardiovascular morbidity and mortality in type 1 diabetic patients with diabetic nephropathy. Diabetes Care 29:334-339
2. Bar-Or O, Rowland TW (eds) (2004) Pediatric exercise medicine. Human Kinetics: Champagne, IL
3. Bloomfield DM, Magnano A, Bigger T Jr., Rivadeneira H, Parides M, Steinman RC (2001) Comparison of spontaneous vs. metronome-guided breathing on assessment of vagal modulation using RR variability. Am J Physiol Heart Circ Physiol 280: H1145-H1150
4. Cabellero AE (2003) Endothelial dysfunction in obesity and insulin resistance: a road to diabetes and heart disease. Obes Res 11:1278-1289
5. Celemajer DS, Sorenson KE, Gooch VM, et al. (1992) Non-invasive detection of endothelial dysfunction in children and adults at risk of atherosclerosis. Lancet 340:1111-1115
6. Dyson KS, Shoemaker JK, Hughson RL (2006) Effect of acute sympathetic nervous system activation on flow-mediated dilation of brachial artery. Am J Physiol Heart Circ Physiol 290:H1446-H1453
7. Emdin M, Gastaldelli A, Muscelli E, et al. (2001) Hyperinsulinemia and autonomic nervous system dysfunction in obesity: effects of weight loss. Circulation 103:513-519
8. Engelke KA, Williams MM, Dietz NM, Joyner MJ (1997) Does sympathetic activation blunt nitric oxide-mediated hyperemia in the human forearm? Clin Auton Res 7:85-91
9. Grekin RJ, Dumont CJ, Vollmer AP, Watts SW, Webb RC (1997) Mechanisms in the pressor effect of hepatic portal venous fatty acid infusion. Am J Physiol 273:R324-R330
10. Hijmering ML, Stroes ESG, Olijhoek J, Hutten BA, Blankestijn PJ, Rabelink TJ (2002) Sympathetic activation markedly reduces endothelium-dependent, flow-mediated vasodilation. J Am Coll Cardiol 39:683-688
11. Iellamo F, Tesauro M, Rizza S, et al. (2006) Concomitant impairment of endothelial function and neural cardiovascular regulation in offspring of type 2 diabetic subjects. Hypertension 48:418-423
12. Kelly AS, Kaiser DR, Dengel DR, Bank AJ (2004) Comparison of B-mode and echo tracking methods of assessing flow-mediated dilation. Ultrasound Med Biol 30:1447-1449.
13. Kelly AS, Wetzsteon RJ, Kaiser DR, Steinberger J, Bank AJ, Dengel DR (2004) Inflammation, insulin, and endothelial function in overweight children and adolescents: the role of exercise. J Pediatr 145:731-736
14. Kleiger RE, Miller JP, Bigger JT, Moss AJ (1987) Decreased heart rate variability and its association with increased mortality after acute myocardial infarction. Am J Cardiol 59:256-262
15. Kobayashi K, Akishita M, Yu W, Hashimoto M, Ohni M, Toba K (2004) Interrelationship between non-invasive measurements of atherosclerosis: flow-mediated dilation of brachial artery, carotid intima-media thickness and pulse wave velocity. Atherosclerosis 173:13-18
16. Martini G, Riva P, Rabbia F, et al. (2001) Heart rate variability in childhood obesity. Clin Auton Res 11:87-91
17. Montani JP, Antic V, Yang Z, Dulloo A (2002) Pathways from obesity to hypertension: from the perspective of a vicious triangle. Int J Obes 26:S28-S38
18. Nagai N, Matsumoto T, Kita H, Moritani T (2003) Autonomic nervous system activity and the state and development of obesity in Japanese school children. Obes Res 11:25-32
19. Neunteufl T, Katzenschlager R, Hassan A, et al. (1997) Systemic endothelial dysfunction is related to the extent and severity of coronary artery disease. Atherosclerosis 129:111-118
20. Rabbia F, Silke B, Conterno A, et al. (2003) Assessment of cardiac autonomic modulation during adolescent obesity. Obes Res 11:541-548
21. Riva G, Martini G, Milan A, Paglieri C, Chiandussi L, Veglio F (2001) Obesity and autonomic function in adolescence. Clin Exp Hypertens 23:57-67
22. Scherrer U, Sartori C (2000) Defective nitric oxide synthesis: a link between metabolic insulin resistance, sympathetic overactivity, and cardiovascular morbidity. Eur J Endocrinol 142:315-323
23. Taniyama Y, Griendling KK (2003) Reactive oxygen species in the vasculature: molecular and cellular mechanisms. Hypertension 42:1075-1081
24. Task Force of the European Society of Cardiology, the North American Society of Pacing and Electrophysiology (1996) Heart rate variability: standards of measurement, physiological interpretation, and clinical use. Circulation 93:1043-1065
25. Toni R, Malaguti A, Castorina S, Roti E, Lechan RM (2004) New paradigms in neuroendocrinology: relationships between obesity, systemic inflammation and the neuroendocrine system. J Endocrinol Invest 27:182-186
26. Tounian P, Aggoun Y, Dubern B, et al. (2001) Presence of increased stiffness of the common carotid artery and endothelial dysfunction in severely obese children: a prospective study. Lancet 358:1400-1404
27. Tsuji H, Venditti FJ, Manders ES, et al. (1994) Reduced heart rate variability and mortality risk in an elderly cohort: the Framingham Heart Study. Circulation 91:878-883
28. Woo KS, Chook P, Yu CW, et al. (2004) Overweight in children is associated with arterial endothelial dysfunction and intima-media thickening. Int J Obes 28:852-857
29. Yakinci C, Mungen B, Karabiber H, Tayfun M, Evereklioglu C (2000) Autonomic nervous system functions in obese children. Brain Dev 22:151-153
30. Yudkin JS, Stehouwer CDA, Emeis JJ, Coppack SW (1999) C-reactive protein in healthy subjects: associations with obesity, insulin resistance, and endothelial dysfunction: a potential role for cytokines originating from adipose tissue? Arterioscler Thomb Vasc Biol 19:972-978