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Cruz ML, Weigensberg MJ, Huang TT, et al.: The metabolic syndrome in overweight Hispanic youth and the role in insulin sensitivity. J Clin Endocrinol Metab 2004, 89:108-113. This study demonstrates that insulin resistance is independently related to adverse lipid profile, blood pressure, and abdominal obesity.
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Cruz, M.L.1
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Metabolic disturbances in obesity versus sleep apnea: The importance of visceral obesity and insulin resistance
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Vgontzas AN, Bixler EO, Chrousos GP: Metabolic disturbances in obesity versus sleep apnea: the importance of visceral obesity and insulin resistance. J Intern Med 2003, 254:32-44.
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Change in body mass index from adolescence to young adulthood and increased carotid intima-media thickness at 28 years of age: The Atherosclerosis Risk in Young Adults study
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Oren A, Vos LE, Uiterwaal CS, et al.: Change in body mass index from adolescence to young adulthood and increased carotid intima-media thickness at 28 years of age: the Atherosclerosis Risk in Young Adults study. Int J Obes Relat Metab Disord 2003, 27:1383-1390. This study confirms the tracking of BMI and concomitant increase in CIMT, and importantly the reversal of these changes for those members of the cohort with decreasing BMI through adolescence.
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Int J Obes Relat Metab Disord
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Oren, A.1
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Vos LE, Oren A, Bots ML, et al.: Does a routinely measured blood pressure in young adolescence accurately predict hypertension and total cardiovascular risk in young adulthood? J Hypertens 2003, 21:2027-2034. The findings of this study strengthen the concept that elevated blood pressure in adolescence unfavorably affects cardiovascular risk, as indicated by increased CIMT.
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Raitakari OT, Juonala M, Kähönen M, et al.: Cardiovascular risk factors in childhood and carotid artery intima-media thickness in adulthood: the Cardiovascular Risk Study in Young Finns. JAMA 2003, 290:2277-2283.
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Glowinska B, Urban M, Koput A, et al.: New atherosclerosis risk factors in obese, hypertensive and diabetic children and adolescents. Atherosclerosis 2003, 167:275-286. In this study the levels of "new" cardiovascular risk factors (lipoprotein a, apolipoproteins A-1 and B, homocysteine, fibrinogen, and tissue plasminogen activator) are measured in children and adolescents with "traditional" risk factors (obesity, hypertension, and diabetes)
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Vgontzas AN, Bixler EO, Chrousos GP: Metabolic disturbances in obesity versus sleep apnea: the importance of visceral obesity and insulin resistance. J Intern Med 2003, 254:32-44. This study identifies that obstructive sleep apnea is independently linked to both the metabolic syndrome and abdominal obesity.
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McCrindle, B.W.1
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