The effects of duloxetine on urethral function and sphincter morphology

International Urogynecology Journal

Volumn 18, Issue 7, 2007, Pages 763-767

  Athanasiou, Stavros ^a   Chaliha, Charlotte ^d   Digesu, G A ^c   Sotiropoulou, Myrtia ^a   Georgoulias, Nicolaos ^a   Khullar, Vik ^b   Antsaklis, Aris ^a  

^a UNIVERSITY OF ATHENS   (Greece)

^b ST MARY S HOSPITAL   (United Kingdom)

^c Bassini Hospital   (Italy)

^d NATIONAL HOSPITAL FOR NEUROLOGY AND NEUROSURGERY   (United Kingdom)

Author keywords

Duloxetine; Ultrasound; Urethral pressure profilometry; Urethral retro resistance pressure; Urethral sphincter; Urodynamic stress incontinence

Indexed keywords

DULOXETINE;

ADULT; AGED; ARTICLE; BLADDER SPHINCTER; CONTROLLED STUDY; DRUG MECHANISM; ECHOGRAPHY; FEMALE; HUMAN; MAJOR CLINICAL STUDY; MORPHOLOGY; PATIENT REFERRAL; PRIORITY JOURNAL; QUESTIONNAIRE; STRESS INCONTINENCE; THICKNESS; TREATMENT DURATION; TREATMENT OUTCOME; URETHRA FUNCTION; URETHRA PRESSURE; URODYNAMICS;

EID: 34347402025     PISSN: 09373462     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00192-006-0230-7     Document Type: Article

References (24)

1. Hannestad YS, Rortveit G, Snadvik, Hunskaar S (2000) A community based epidemiological survey of female urinary incontinence: The Norwegian EPINCONT study. J Clin Epidemiol 53:1150-1157
2. Minassian VA, Drutz HP, Al-Badr A (2003) Urinary incontinence as a worldwide problem. Int J Gynecol Obstet 82:327-328
3. Kinchen KS, Burgio K, Diokno AC, Fultz NH, Bump RC (2003) Burden of stress urinary incontinence for community-dwelling women. Am J Obstet Gynecol 189:1275-1282
4. Hunskaar S, Lose G, Sykes D, Voss S (2004) The prevalence of urinary incontinence in women in four European countries. BJU Int 93:324-330
5. Largo-Janssen T, van Weel C (1998) Long-term effect of treatment of female incontinence in general practice. Br J Gen Pract 48:1735-1738
6. Wilson PD, Bo K, Hay-Smith J et al (2002) Conservative treatment in women. In: Abrams P, Khoury S, Wein A (eds) Incontinence, 2nd edn. Health Publications, Plymouth, UK, pp 573-624
7. Pesce F (2004) Current management of stress urinary incontinence. BJU Int 94(Suppl 1):8-13
8. Thor KB, Katofiasc MA (1995) Effects of duloxetine, a combined serotonin and norepinephrine reuptake inhibitor on central neural control of lower urinary tract function in the chlorase-anesthetised female cat. J Pharmacol Exp Ther 274:1014-1024
9. Danuseer H, Bemis K, Thor KB (1995) Pharmacological analysis of the noradrenergic control of central sympathetic and somatic reflexes controlling the lower urinary tract in the anesthetized cat. J Urol 274:820-825
10. Norton PA, Zinner NR, Yalcin I, Bump RC (2002) Duloxetine versus placebo in the treatment of stress urinary incontinence. Am J Obstet Gynecol 187:40-48
11. Dmochowski RR, Miklos JR, Norton PA, Zinner NR, Yalcin I, Bump RC (2003) Duloxetine versus placebo for the treatment of North American women with stress urinary incontinence. J Urol 170:1259-1263
12. Millard RJ, Moore K, Rencken R, Yalcin I, Bump RC (2004) Duloxetine vs placebo in the treatment of stress urinary incontinence: A four continent randomized clinical trial. BJU Int 92:311-318
13. van Kerrebroeck P, Abrams P, Lange R et al (2004) Duloxetine versus placebo in the treatment of European and Canadian women with stress urinary incontinence. BJOG 111:249-257
14. Cardozo L, Drutz HP, Baygani SK, Bump RC (2004) Pharmacological treatment of women awaiting surgery for stress urinary incontinence. Obstet Gynecol 104:511-519
15. Kelleher CJ, Cardozo LD, Khullar V, Salvatore S (1997) A new questionnaire to assess the quality of life of urinary incontinent women. Br J Obstet Gynaecol 104:1374-1379
16. Guy W (1976) EGDEU assessment manual for psychopharmacology. Rockville (MD): National Institute of Mental Health. US Department of Health, Education and Welfare, pp 218-222
17. Yalcin I, Bump RC (2003) Validation of two global impression questionnaires for incontinence. Am J Obstet Gynecol 189:98-101
18. Slack M, Culligan P, Tracey M, Hunisker K, Patel B, Sumeray M (2004) Relationship of urethral retro-resistance pressure to urodynamic measurements and incontinence severity. Neurourol Urodyn 23:109-114
19. Slack M, Tracey M, Hunsicker K, Godwin A, Patel B, Sumeray M (2004) Urethral retro-resistance pressure: A new clinical measure of urethral function. Neurourol Urodyn 23(7):656-671
20. Hilton P, Stanton SL (1983) Urethral pressure measurement by microtransducer: The results in symptom-free women and in those with genuine stress incontinence. Br J Obstet Gynaecol 90:919-933
21. Abrams P, Cardozo L, Fall M, Griffiths D, Rosier P, Ulmsten U et al (2002) The standardization of terminology of lower urinary tract function: Report from the standardization sub-committee of the International Continence Society. Neurourol Urodyn 21:167-178
22. Boy S, Reitz A, Wirth B, Karsenty G, Knapp P, Schurch B (2005) Facilitatory neuromodulative effect of duloxetine on urethral sphincter motor neurones in healthy females. Eur Urol Suppl 4:253, Abstract 998
23. Bump RC, Benson JT, Brubaker L et al (2004) Biomechanical and electrophysiological effects of duloxetine in women with stress urinary incontinence. Neurourol Urodynam 23, Abstract 269
24. Athanasiou S, Khullar V, Boos K, Salvatore S, Cardozo L (1999) Imaging the urethral sphincter with three-dimensional ultrasound. Obstet Gynecol 94:295-301