Potent macrocyclic antagonists to the motilin receptor presenting novel unnatural amino acids

Bioorganic and Medicinal Chemistry Letters

Volumn 17, Issue 15, 2007, Pages 4187-4190

  Marsault, Eric ^a   Benakli, Kamel ^a   Beaubien, Sylvie ^a   Saint Louis, Carl ^a   Déziel, Robert ^a   Fraser, Graeme ^a  

^a Tranzyme Pharma Inc   (Canada)

Author keywords

Antagonist; Macrocycles; Motilin; Peptidomimetics

Indexed keywords

AMINO ACID DERIVATIVE; HORMONE RECEPTOR; HORMONE RECEPTOR BLOCKING AGENT; MACROCYCLIC COMPOUND; MOTILIN; MOTILIN RECEPTOR ANTAGONIST; TRIPEPTIDE; UNCLASSIFIED DRUG;

ARTICLE; DRUG ACTIVITY; DRUG STRUCTURE; STRUCTURE ANALYSIS;

AMINO ACIDS; CYCLIZATION; MACROCYCLIC COMPOUNDS; RECEPTORS, GASTROINTESTINAL HORMONE; RECEPTORS, NEUROPEPTIDE;

EID: 34347401398     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmcl.2007.05.043     Document Type: Article

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