Stomach-specific drug delivery of 5-fluorouracil using floating alginate beads

AAPS PharmSciTech

Volumn 8, Issue 2, 2007, Pages

  Shishu, ^a   Gupta, Neeta ^a   Aggarwal, Nidhi ^a  

^a PANJAB UNIVERSITY   (India)

Author keywords

5 Fluorouracil; Buoyancy; Calcium alginate beads; Floating dosage form; Gastric residence time

Indexed keywords

ALGINIC ACID; BENZO[A]PYRENE; CALCIUM ALGINATE; CALCIUM CARBONATE; CALCIUM CHLORIDE; CALCIUM ION; CARBON DIOXIDE; CARBONIC ACID; FLUOROURACIL; HYDROXYPROPYLMETHYLCELLULOSE; POLYMER; GLUCURONIC ACID; HEXURONIC ACID;

ACIDIFICATION; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CANCER INHIBITION; CONTROLLED STUDY; DISPERSION; DRUG BIOAVAILABILITY; DRUG DELIVERY SYSTEM; DRUG DESIGN; DRUG DOSAGE FORM COMPARISON; DRUG EFFICACY; DRUG RELEASE; DRUG SCREENING; DRUG SYNTHESIS; FEMALE; GELATION; IN VIVO STUDY; MOLECULAR WEIGHT; MOUSE; NONHUMAN; STOMACH CANCER; SURFACE PROPERTY; TABLET FORMULATION; ANIMAL; BAGG ALBINO MOUSE; CHEMISTRY; DELAYED RELEASE FORMULATION; PARTICLE SIZE; SOLUBILITY; STOMACH TUMOR;

ALGINATES; ANIMALS; CHEMISTRY, PHARMACEUTICAL; DELAYED-ACTION PREPARATIONS; FEMALE; FLUOROURACIL; GLUCURONIC ACID; HEXURONIC ACIDS; MICE; MICE, INBRED BALB C; PARTICLE SIZE; SOLUBILITY; STOMACH NEOPLASMS; SURFACE PROPERTIES;

EID: 34347393858     PISSN: None     EISSN: 15309932     Source Type: Journal    
DOI: 10.1208/pt0802048     Document Type: Article

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