NADPH oxidase polymorphisms in cerebral small vessel disease

Cerebrovascular Diseases

Volumn 24, Issue 1, 2007, Pages 135-138

  Khan, Usman ^a   Bevan, Steve ^a   Markus, Hugh S ^a  

^a ST GEORGE'S UNIVERSITY OF LONDON   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE;

ADULT; ARTICLE; BRAIN INFARCTION; BRAIN LACUNAR INFARCTION; CEREBROVASCULAR DISEASE; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DOPPLER ECHOGRAPHY; ELECTROCARDIOGRAPHY; ENZYME POLYMORPHISM; FEMALE; GENOTYPE; HUMAN; LEUKOARAIOSIS; MAGNETIC RESONANCE ANGIOGRAPHY; MAJOR CLINICAL STUDY; MALE; MICROANGIOPATHY; NEUROIMAGING; PRIORITY JOURNAL; STATISTICAL ANALYSIS;

AGED; CASE-CONTROL STUDIES; CEREBRAL ARTERIAL DISEASES; FEMALE; GENE FREQUENCY; GENETIC PREDISPOSITION TO DISEASE; HAPLOTYPES; HUMANS; MALE; MIDDLE AGED; NADPH OXIDASE; ODDS RATIO; POLYMORPHISM, GENETIC; RISK ASSESSMENT; RISK FACTORS;

EID: 34347383194     PISSN: 10159770     EISSN: None     Source Type: Journal    
DOI: 10.1159/000103615     Document Type: Article

References (12)

1. Boiten J, Lodder J, Kessels F: Two clinically distinct lacunar infarct entities? A hypothesis. Stroke 1993;24:652-656.
2. Carmelli D, DeCarli C, Swan GE, Jack LM, Reed T, Wolf PA, Miller BL: Evidence for genetic variance in white matter hyperintensity volume in normal elderly male twins. Stroke 1998;29:1177-1181.
3. Jerrard-Dunne P, Cloud G, Hassan A, Markus HS: Evaluating the genetic component of ischemic stroke subtypes: a family history study. Stroke 2003;34:1364-1369.
4. Hassan A, Hunt BJ, O'Sullivan M, Parmar K, Bamford JM, Briley D, Brown MM, Thomas DJ, Markus HS: Markers of endothelial dysfunction in lacunar infarction and ischaemic leukoaraiosis. Brain 2003;126:424-432.
5. Cai H, Harrison DG: Endothelial dysfunction in cardiovascular diseases: the role of oxidant stress. Circ Res 2000;87:840-844.
6. Soccio M, Toniato E, Evangelista V, Carluccio M, De Caterina R: Oxidative stress and cardiovascular risk: the role of vascular NAD(P)H oxidase and its genetic variants. Eur J Clin Invest 2005;35:305-314.
7. Ito D, Murata M, Watanabe K, Yoshida T, Saito I, Tanahashi N, Fukuuchi Y: C242T polymorphism of NADPH oxidase p22 PHOX gene and ischemic cerebrovascular disease in the Japanese population. Stroke 2000;31:936-939.
8. Shimo-Nakanishi Y, Hasebe T, Suzuki A, Mochizuki H, Nomiyama T, Tanaka Y, Nagaoka I, Mizuno Y, Urabe T: Functional effects of NAD(P)H oxidase p22(phox) C242T mutation in human leukocytes and association with thrombotic cerebral infarction. Atherosclerosis 2004;175:109-115.
9. Adams HP Jr, Bendixen BH, Kappelle LJ, Biller J, Love BB, Gordon DL, Marsh EE 3rd: Classification of subtype of acute ischemic stroke. Definitions for use in a multicenter clinical trial. TOAST. Trial of Org 10172 in Acute Stroke Treatment. Stroke 1993;24:35-41.
10. Stephens M, Donnelly P: A comparison of bayesian methods for haplotype reconstruction from population genotype data. Am J Hum Genet 2003;73:1162-1169.
11. Barrett JC, Fry B, Maller J, Daly MJ: Haploview: analysis and visualization of LD and haplotype maps. Bioinformatics 2005;21:263-265.
12. Krex D, Ziegler A, Konig IR, Schackert HK, Schackert G: Polymorphisms of the NADPH oxidase P22PHOX gene in a Caucasian population with intracranial aneurysms. Cerebrovasc Dis 2003;16:363-368.