Association of polymorphism of TLR4 and CD14 genes with gastroduodenal diseases in Japan

Inflammopharmacology

Volumn 15, Issue 3, 2007, Pages 124-128

  Tahara, T ^a   Arisawa, T ^a   Shibata, T ^a   Hirata, I ^a   Nakano, H ^a  

^a FUJITA HEALTH UNIVERSITY SCHOOL OF MEDICINE   (Japan)

Author keywords

CD14; Gastric cancer; H. pylori; Polymorphism; TLR4

Indexed keywords

ASPARTIC ACID; CD14 ANTIGEN; GLYCINE; ISOLEUCINE; THREONINE; TOLL LIKE RECEPTOR 4;

ADULT; AGE DISTRIBUTION; AGED; ARTICLE; CANCER RISK; CONFIDENCE INTERVAL; CONTROLLED STUDY; DNA POLYMORPHISM; FEMALE; GASTRITIS; GASTROENTERITIS; GENE FREQUENCY; GENETIC ASSOCIATION; GENOTYPE; HELICOBACTER INFECTION; HISTOLOGY; HUMAN; HUMAN TISSUE; JAPAN; MAJOR CLINICAL STUDY; MALE; PEPTIC ULCER; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; RESTRICTION FRAGMENT LENGTH POLYMORPHISM; SCORING SYSTEM; SEX RATIO; STOMACH CANCER; STOMACH MUCOSA;

ADULT; AGED; ANTIGENS, CD14; FEMALE; GASTRITIS; GENOTYPE; HELICOBACTER INFECTIONS; HELICOBACTER PYLORI; HUMANS; MALE; MIDDLE AGED; POLYMORPHISM, GENETIC; RISK FACTORS; STOMACH NEOPLASMS; TOLL-LIKE RECEPTOR 4;

EID: 34347380128     PISSN: 09254692     EISSN: None     Source Type: Journal    
DOI: 10.1007/s10787-006-1567-8     Document Type: Article

References (24)

1. Arbour, N. C., Lorenz, E., Schutte, B. C. et al. (2000) TLR4 mutations are associated with endotoxin hyporesponsiveness in humans. Nat. Genet. 25, 187-191.
2. Baldini, M., Lohman, I. C., Halonen, M. et al. (1999) A Polymorphism* in the 5′ flanking region of the CD14 gene is associated with circulating soluble CD14 levels and with total serum immunoglobulin E. Am. J. Respir. Cell. Mol. Biol. 20, 976-983.
3. Bamford, K. B., Fan, X., and Crowe, S. E. (1998) Lymphocytes in the human gastric mucosa during Helicobacter pylori have a T helper cell 1 phenotype. Gastroenterology. 114, 482-492.
4. Bliss, C. M. Jr., Golenbock, D. T., Keates, S. et al. (1998) Helicobacter pylori lipopolysaccharide binds to CD14 and stimulates release of interleukin-8, epithelial neutrophil-activating peptide 78, and monocyte chemotactic protein 1 by human monocytes. Infect. Immun. 66, 5357-5363.
5. Chao, Y. C., Young, T. H., Tang, H. S. et al. (1997) Alcoholism and alcoholic organ damage and genetic polymorphisms of alcohol metabolizing enzymes in Chinese patients. Hepatology. 25, 112-127.
6. Correa, P. (1995) Helicobacter pylori and gastric carcinogenesis. Am. J. Surg. Pathol. 19 (Suppl), S37-43.
7. Correa, P., Haenszel. W., Cuello, C. (1975) A model for gastric cancer epidemiology, Lancet. 2, 58-60.
8. Dixon, M. F., Genta, R. M., Yardley, J. H. et al. (1996) Classification and grading of gastritis. The updated Sydney System. International Workshop on the Histopathology of Gastritis, Houston 1994. Am. J. Surg. Pathol. 20, 1161-1181.
9. Fernandez-Real, J. M., Broch, M., Richart, C., Vendrell, J. et al. (2003) CD14 monocyte receptor, involved in the inflammatory cascade, and insulin sensitivity. J. Clin. Endocrinol. Metab. 88, 1780-1784.
10. Guo, Q., Zhu, J., Xia, B. et al. (2006) Polymorphism of CD14 gene but not the mutation of TLR4 gene is associated with colorectal cancer in Chinese patients. J. Gastroenterol.Hepatol. 21, 92-97.
11. Hubacek, J. A., Rothe, G., Pit'ha, J. et al. (1999) C(-260) - >T polymorphism in the promoter of the CD14 monocyte receptor gene as a risk factor for myocardial infarction. Circulation. 99, 3218-3220.
12. Ito, D., Murata, M., Tanahashi, N. et al. (2000) Polymorphism in the promoter of lipopolysaccharide receptor CD14 and ischemic cerebrovascular disease. Stroke. 31, 2661-2664.
13. Janeway, C. A. Jr. and Medzhitov, R. (1998) Introduction: the role of innate immunity in the adaptive immune response. Semin Immunol. 10, 349-350.
14. Karhukorpi, J., Yan, Y., Niemela, S. et al. (2002) Effect of CD14 promoter polymorphism and H. pylori infection and its clinical outcomes on circulating CD14. Clin. Exp. Immunol. 128, 326-332.
15. Lauren, P. (1965) The two histrogical main types of gastric carcinoma: diffuse and so-called intestinal-type carcinoma. An attempt at a histo-clinical classification. Acta. Pathol. Microbiol. Scand. 64, 31-49.
16. LeVan, T. D., Bloom , J. W., Bailey, T. J. et al. (2001) A common single nucleotide polymorphism in the CD14 promoter decreases the affinity of Sp protein binding and enhances transcriptional activity. J. Immunol. 167, 5838-5844.
17. Lorenz, E., Frees, K. L. and Schwartz, D. A. (2001) Determination of the TLR4 genotype using allele-specific PCR. Biotechniques. 31, 22-24.
18. Risley, P., Jerrard-Dunne, P, Sitzer, M. et al. (2003) Carotid Atherosclerosis Progression Study. Promoter polymorphism in the endotoxin receptor (CD14) is associated with increased carotid atherosclerosis only in smokers: the Carotid Atherosclerosis Progression Study (CAPS). Stroke. 34, 600-604.
19. Rietschel, E. T., Kirikae, T., Schade, F. U. et al. (1994) Bacterial endotoxin: molecular relationships of structure to activity and function. FASEB J. 8, 217-225.
20. Sweet, M. J. and Hume, D. A. (1996) Endotoxin signal transduction in macrophages. J. Leukoc. Biol. 60, 8-26.
21. Schmausser, B., Andrulis, M., Endrich, S. et al. (2004) Expression and subcellular distribution of toll-like receptors TLR4, TLR5 and TLR9 on the gastric epithelium in Helicobacter pylori infection. Clin. Exp. Immunol. 136, 521-526.
22. Uemura, N., Okamoto, S., Yamamoto, S. et al. (2001) Helicobacter pylori infection and the development of gastric cancer. N. Engl. J. Med. 345, 784-789.
23. Ulevitch, R. J. and Tobias, P. S. (1995) Receptor-dependent mechanisms of cell stimulation by bacterial endotoxin. Annu. Rev. Immunol. 13, 437-457.
24. Wright, S. D., Ramos, R. A., Tobias, P. S. et al. (1990) CD14, a receptor for complexes of lipopolysaccharide (LPS) and LPS binding protein. Science. 249, 1431-1433.