Metoprolol CR/XL improves systolic and diastolic left ventricular function in patients with chronic heart failure

Echocardiography

Volumn 21, Issue 3, 2004, Pages 215-223

  Hole, Torstein ^a,f   Frøland, Gisle ^b   Gullestad, Lars ^c   Offstad, Jon ^d   Skjærpe, Terje ^e  

^a Alesund Hospital   (Norway)

^b Section of Cardiology   (Norway)

^c VESTRE VIKEN HOSPITAL TRUST   (Norway)

^d OSLO UNIVERSITY HOSPITAL   (Norway)

^e TRONDHEIM UNIVERSITY HOSPITAL   (Norway)

^f Alesund Hospital   (Norway)

Author keywords

Beta blockade; Diastolic function; Doppler; Echocardiography; Heart failure; Systolic function

Indexed keywords

METOPROLOL;

ADULT; AGED; ARTICLE; CLINICAL TRIAL; COLOR ULTRASOUND FLOWMETRY; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DECELERATION; DIASTOLE; DRUG DOSE REGIMEN; DRUG EFFECT; DRUG EFFICACY; ECHOCARDIOGRAPHY; FEMALE; HEART FAILURE; HEART LEFT VENTRICLE EJECTION FRACTION; HEART LEFT VENTRICLE FUNCTION; HUMAN; MAJOR CLINICAL STUDY; MALE; PRIORITY JOURNAL; RANDOMIZATION; SUSTAINED DRUG RELEASE; SYSTOLE;

ADRENERGIC BETA-ANTAGONISTS; AGED; ECHOCARDIOGRAPHY; FEMALE; HEART FAILURE, CONGESTIVE; HUMANS; MALE; METOPROLOL; MYOCARDIAL CONTRACTION; VENTRICULAR DYSFUNCTION, LEFT;

EID: 1842678180     PISSN: 07422822     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.0742-2822.2004.03102.x     Document Type: Article

References (44)

1. CIBIS-II investigators and committees: The Cardiac Insufficiency Bisoprolol Study II (CIBIS-II): A randomised trial. Lancet 1999;353:9-13.
2. MERIT-HF study group: Effect of metoprolol CB/XL in chronic heart failure: Metoprolol CR/XL Randomised Intervention Trial in Congestive Heart Failure (MERIT-HF). Lancet 1999;353:2001-2007.
3. Packer M, Bristow M, Cohn JN, et al. for the U.S. Carvedilol Heart Failure Study Group: The effect of carvedilol on morbidity and mortality in patients with chronic heart failure. N Engl J Med 1996;334:1349-1355.
4. Australia/New Zealand Heart Failure Research Collaborative Group: Randomised, placebo-controlled trial of carvedilol in patients with congestive heart failure due to ischemic heart disease. Lancet 1997;349:375-380.
5. Packer M, Coats AJS, Fowler MB, et al: Effect of carvedilol on survival in severe chronic heart failure. N Engl J Med 2001;344:1651-1658.
6. Eichhorn EJ, Hesch CM, Barnett JH, et al: Effect of metoprolol on myocardial function and energetics in patients with non-ischemic dilated cardiomyopathy: A randomised, double-blind, placebo-controlled study. J Am Coll Cardiol 1994;24:1310-1320.
7. Wisenbaugh T, Katz I, Davis J, et al: Long-term (3 month) effects of a new beta-blocker (nebivolol) on cardiac performance in dilated cardiomyopathy. J Am Coll Cardiol 1993;21:1094-1100.
8. Bristow MR, Gilbert EM, Abraham WT, et al. for the MOCHA investigators: Carvedilol produces dose-related improvements in left ventricular function and survival in subjects with chronic heart failure. Circulation 1996;94:2807-2816.
9. Hall SA, Cigarroa CG, Marcoux L, et al: Time course of improvement in left ventricular function, mass, and geometry in patients with congestive heart failure treated with β-adrenergic blockade. J Am Coll Cardiol 1995;25:1154-1161.
10. Andersson B, Caidal K, di Lenarda A, et al: Changes in early and late diastolic filling patterns induced by long-term adrenergic β-blockade in patients with idiopathic dilated cardiomyopathy. Circulation 1996;94:673-682.
11. The RESOLVD Investigators: Effects of metoprolol CR in patients with ischemic and dilated cardiomyopathy. The randomised evaluation of strategies for left ventricular dysfunction pilot study. Circulation 2000;101:378-384.
12. Groenning BA, Nilsson JC, Sondergaard L, et al: Antiremodeling effects on the left ventricle during beta-blockade with metoprolol in the treatment of chronic heart failure. J Am Coll Cardiol 2000;36:2072-2080.
13. Eichhorn EJ, Grayburn PA: β-blocker improvement in diastolic performance: The yin and yang of ventricular function changes. Am Heart J 2000;139:584-586.
14. Eichhorn EJ, Bedotta JB, Malloy CR, et al: Effect of beta-adrenergic blockade on myocardial function and energetics in congestive heart failure: Improvements in hemodynamic, contractile, and diastolic performance with bucindolol. Circulation 1990;82:473-483.
15. Kim MH, Devlin WH, Das SK, et al: Effects of β-adrenergic blocking therapy on left ventricular diastolic relaxation properties in patients with dilated cardiomyopathy. Circulation 1999;100:729-735.
16. Capomolla S, Febo O, Gnemmi M, et al: β-blockade therapy in chronic heart failure: Diastolic function and mitral regurgitation improvement by carvedilol. Am Heart J 2000;139:596-608.
17. Schiller NB, Shah PM, Crawford M, et al: Recommendations for quantification of the left ventricle by two-dimensional echocardiography. J Am Soc Echocardiogr 1989;2:358-368.
18. Otterstad JE, Frøland G, St John Sutton M, et al: Accuracy and reproducibility of biplane two-dimensional echocardiographic measurements of left ventricular dimensions and function. Eur Heart J 1997;18:507-513.
19. Hole T, Urheim S, Skjærpe T: Intra-and interobserver reproducibility of transthoracic pulmonary venous Doppler flow indices after acute myocardial infarction. Eur J Echocardiogr 2002;3:32-38, doi: 10.1053/euje.2001.0102.
20. Hand D, Crowder M: Practical Longitudinal Data Analysis. New York, Chapman & Hall/CRC, 1999.
21. Little RC, Milliken GA, Stroup WW, et al: SAS System for Mixed Models. Cary, NC, SAS Institute 1996.
22. Rakowski H, Appleton CP, Chan KL, et al: Canadian consensus recommendations for the measurement and reporting of diastolic dysfunction by echocardiography: From the Investigators of Consensus on Diastolic Dysfunction by Echocardiography. J Am Soc Echocardiogr 1996;9:736-760.
23. Hjalmarson Å, Goldstein S, Fagerberg B, et al. for the MERIT-HF Study Group: Effects of controlled-release metoprolol on total mortality, hospitaliszations, and well-being in patients with heart failure. JAMA 2000;283:1295-1302.
24. Sutton MStJ, Pfeffer MA, Plappert T, et al: Quantitative two-dimensional echocardiographic measurements are major predictors of adverse cardiovascular events after acute myocardial infarction. Circulation 1994;89:68-75.
25. Gaudron P, Ellis C, Kugler I, et al: Progressive left ventricular dysfunction and remodelling after myocardial infarction. Potential mechanisms and early predictors. Circulation 1993;87:755-763.
26. Petersen LC, Gadsbøll N, Stadeager C, et al: Changes in left and right ventricular performance and volumes in 7-year survivors of acute myocardial infarction. Am J Cardiol 1995;75:659-664.
27. Gadsbøll N, Høilund-Carlsen PF, Badsberg JH, et al: Left ventricular volumes in the recovery phase after acute myocardial infarction: Relation to infarct locatrion, left ventricular function and one-year cardiac mortality. Eur Heart J 1990;11:791-799.
28. White HD, Norris RM, Brown MA, et al: Left ventricular volume as the major determinant of survival after recovery from myocardial infarction. Circulation 1987;76:44-51.
29. Wong M, Johnson G, Shabetai R, et al: Echocardiographic variables as prognostic indicators and therapeutic monitors in chronic congestive heart failure. Veterans Affair Cooperative Studies VHeFT I and II. VHeFT VA Cooperative Study Group. Circulation 1993;87(Suppl. 6):v165-v170.
30. Pfeffer ME, Braunwald E, Moye LA, on behalf of the SAVE investigators: Effects of captopril on mortality and morbidity in patients with left ventricular dysfunction after myocardial infarction: Results of the survival and ventricular enlargement trial. N Engl J Med 1992;327:669-677.
31. Chuang ML, Hibberd MG, Salton CJ, et al: Importance of imaging method over imaging modality in non-invasive determination of left ventricular volumes and ejection fraction. J Am Coll Cardiol 2000;35:477-484.
32. Appleton CP, Hatle LK: The natural history of left ventricular filling abnormalities: Assessment by two-dimensional and Doppler echocardiography. Echocardiography 1992;9:437-457.
33. Giannuzzi P, Imparato A, Temporelli PL, et al: Doppler-derived mitral deceleration time of early filling as strong predictor of pulmonary capillary wedge pressure in postinfarction patients with left ventricular systolic dysfunction. J Am Coll Cardiol 1994;23:1630-1637.
34. Pozzoli M, Capomolla S, Pinna G, et al: Doppler echocardiography reliably predicts pulmonary artery wedge pressure in patients with chronic heart failure with and without mitral regurgitation. J Am Coll Cardiol 1996;27:883-893.
35. Klein AL, Hatle LK, Taliercio CP, et al: Prognostic significance of Doppler measures of diastolic function in cardiac amyloidosis. A Doppler echocardiographic study. Circulation 1991;83:808-816.
36. Shen WF, Tribouilloy C, Rey JL, et al: Prognostic significance of Doppler-derived left ventricular diastolic filling variables in dilated cardiomyopathy. Am Heart J 1992;124:1524-1533.
37. Xie GY, Berk MR, Smith MD, et al: Prognostic value of transmitral flow patterns in patients with congestive heart failure. J Am Coll Cardiol 1994;24:132-139.
38. Giannuzzi P, Temporelli PL, Bosimini E, et al: Independent and incremental prognostic value of Doppler-derived mitral deceleration time of early filling in both symptomatic and asymptomatic patients with left ventricular dysfunction. J Am Coll Cardiol 1996;28:383-390.
39. Traversi E, Pozzoli M, Cioffi G, et al: Mitral flow velocity changes after 6 months of optimised therapy provide important hemodynamic and prognostic information in patients with chronic heart failure. Am Heart J 1996;132:809-819.
40. Nuti R, Boni A, Baldini U, et al: Duration of mitral inflow A-wave increases sensitivity of Doppler estimation of filling pressure in the elderly with dilated cardiomyopathy. Eur J Echocardiography 2001;2(Suppl. A):S9.
41. Paraskevaidis IA, Tsiapras DP, Karavolias GK, et al: Doppler-derived left ventricular end-diastolic pressure prediction model using the combined analysisi of mitral and pulmonary A waves in patients with coronary artery disease and preserved left ventricular systolic function. Am J Cardiol 2002;90:720-724.
42. Andersson B, Strømblad SO, Lomsky M, et al: Heart rate dependency of cardiac performance in heart failure patients treated with metoprolol. Eur Heart J 1999;20:575-583.
43. Lechat P, Hulot JS, Escolano S, et al. on behalf of the CIBIS II Investigators: Heart rate and cardiac rhythm relationships with bisoprolol benefit in chronic heart failure in CIBIS II trial. Circulation 2001;103:1428-1433.
44. Arnold RH, Kotlyar E, Hayward C, et al: Relation between heart rate, heart rhythm, and reverse left ventricular remodelling in response to carvedilol in patients with chronic heart failure: A single centre, observational study. Heart 2003;89:293-298.