Stabilization of a transition-state analogue at the active site of yeast cytosine deaminase: Importance of proton transfers

Journal of Physical Chemistry B

Volumn 111, Issue 23, 2007, Pages 6501-6506

  Xu, Qin ^a   Guo, Haobo ^a   Gorin, Andrey ^b   Guo, Hong ^a  

^a UNIVERSITY OF TENNESSEE   (United States)

^b OAK RIDGE NATIONAL LABORATORY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BINDING SITES; KETONES; MOLECULAR DYNAMICS; NUCLEOPHILES; PROTON TRANSFER; QUANTUM THEORY; YEAST;

ALKOXIDE; FREE ENERGY SIMULATIONS; HYDROXIDE GROUP; PYRIMIDIN-2-ONE;

ENZYME ACTIVITY;

EID: 34347358491     PISSN: 15206106     EISSN: None     Source Type: Journal    
DOI: 10.1021/jp0670743     Document Type: Article

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