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Volumn 34, Issue 6, 2006, Pages 716-722

The effect of cyclosporin A on alveolar bone in rats subjected to experimental periodontal disease

Author keywords

Adverse effects; Alveolar bone; Cyclosporine A; Periodontal disease; Rats

Indexed keywords

ALKALINE PHOSPHATASE; CALCIUM; CYCLOSPORIN; IMMUNOSUPPRESSIVE AGENT;

EID: 34347357205     PISSN: 01926233     EISSN: 15331601     Source Type: Journal    
DOI: 10.1080/01926230600826269     Document Type: Article
Times cited : (10)

References (44)
  • 1
    • 0021760566 scopus 로고
    • Gingival hyperplasia associated with cyclosporin A. A report of two cases
    • Adams, D., and Davies, G. (1984). Gingival hyperplasia associated with cyclosporin A. A report of two cases. Br Dent J 157, 89-90.
    • (1984) Br Dent J , vol.157 , pp. 89-90
    • Adams, D.1    Davies, G.2
  • 2
    • 0024463342 scopus 로고
    • Regulation of human gingival fibroblast growth and synthetic activity by cyclosporine-A in vitro
    • Bartold, P. M. (1989). Regulation of human gingival fibroblast growth and synthetic activity by cyclosporine-A in vitro. J Periodontal Res 24, 314-21.
    • (1989) J Periodontal Res , vol.24 , pp. 314-321
    • Bartold, P.M.1
  • 3
    • 0019418366 scopus 로고
    • Cyclosporin A mediates immunosuppression of primary cytotoxic T cell responses by impairing the release of interleukin 1 and interleukin 2
    • DOI 10.1002/eji.1830110812
    • Bunjes, D., Hardt, C., Rollinghoff, M., and Wagner, H. (1981). Cyclosporin A mediates immunosuppression of primary cytotoxic T cell responses by impairing the release of interleukin 1 and interleukin 2. Eur J Immunol 11, 657-61. (Pubitemid 11057615)
    • (1981) European Journal of Immunology , vol.11 , Issue.8 , pp. 657-661
    • Bunjes, D.1    Hardt, C.2    Roellinghoff, M.3    Wagner, H.4
  • 4
    • 0018688143 scopus 로고
    • Cyclosporin A initially as the only immunosuppressant in 34 recipients of cadaveric organs: 32 Kidneys, 2 pancreases, and 2 livers
    • Calne, R. Y., Rolles, K., White, D. J., Thiru, S., Evans, D. B., McMaster, P., Dunn, D. C., Craddock, G. N., Henderson, R. G., Aziz, S., and Lewis, P. (1979). Cyclosporin A initially as the only immunosupresant 34 recipients of cadaveric organs: 32 kidneys, 2 pancreases and 2 livers. Lancet 2, 1033-6. (Pubitemid 10213970)
    • (1979) Lancet , vol.2 , Issue.8151 , pp. 1033-1036
    • Calne, R.Y.1    Rolles, K.2    White, D.J.G.3
  • 6
    • 33646199031 scopus 로고    scopus 로고
    • Increased expression of vascular endothelial growth factor in cyclosporin A-induced gingival overgrowth in rats
    • DOI 10.1902/jop.2006.77.1.54
    • Cetinkaya, B. O., Acikgoz, G., Ayas, B., Aliyev, E., and Sakallioglu, E. E. (2006a). Increased expression of vascular endothelial growth factor in cyclosporin A-induced gingival overgrowth in rats. J Periodontol 77, 54-60. (Pubitemid 43949657)
    • (2006) Journal of Periodontology , vol.77 , Issue.1 , pp. 54-60
    • Cetinkaya, B.O.1    Acikgoz, G.2    Ayas, B.3    Aliyev, E.4    Sakallioglu, E.E.5
  • 7
    • 33747600645 scopus 로고    scopus 로고
    • The relationship between Proliferating Cell Nuclear Antigen expression and histomorphometrical alterations in cyclosporin A-induced gingival overgrowth in rats
    • Cetinkaya, B. O., Acikgoz, G., Aydin, O., Korkmaz, A., and Keles, G. C. (2006b). The relationship between Proliferating Cell Nuclear Antigen expression and histomorphometrical alterations in cyclosporin A-induced gingival overgrowth in rats. Toxicol Pathol 34, 180-6.
    • (2006) Toxicol Pathol , vol.34 , pp. 180-186
    • Cetinkaya, B.O.1    Acikgoz, G.2    Aydin, O.3    Korkmaz, A.4    Keles, G.C.5
  • 8
    • 8044228552 scopus 로고
    • Role of interleukin-2 in periodontal bone loss in the ligated rats
    • Cox D. S., Williams-Miller C., and Nadip, T. (1987). Role of interleukin-2 in periodontal bone loss in the ligated rats. J Periodontol 58, 130.
    • (1987) J Periodontol , vol.58 , pp. 130
    • Cox, D.S.1    Williams-Miller, C.2    Nadip, T.3
  • 10
    • 0021706396 scopus 로고
    • Cyclosporine therapy. Its significance to the periodontist
    • Daley, T. D., and Wysocki, G. P. (1984). Cyclosporine therapy. Its significance to the periodontist. J Periodontol 55, 708-12. (Pubitemid 15152387)
    • (1984) Journal of Periodontology , vol.55 , Issue.12 , pp. 708-712
    • Daley, T.D.1    Wysocki, G.P.2
  • 11
    • 0022619315 scopus 로고
    • Cyclosporine A: Effectiveness and toxicity in a rat model
    • Dieperink, H., Kemp, E., Leyssac, P. P., and Starklint, H. (1986). Cyclosporine A: effectiveness and toxicity in a rat model. Clin Nephrol 25, 46-50.
    • (1986) Clin Nephrol , vol.25 , pp. 46-50
    • Dieperink, H.1    Kemp, E.2    Leyssac, P.P.3    Starklint, H.4
  • 12
    • 0023847966 scopus 로고
    • Cyclosporin in rheumatoid arthritis: A double blind, placebo controlled study in 52 patients
    • Dougados, M., Awada, H., and Amor, B. (1988). Cyclosporin in rheumatoid arthritis: a double blind, placebo controlled study in 52 patients. Ann Rheum Dis 47, 127-33. (Pubitemid 18046617)
    • (1988) Annals of the Rheumatic Diseases , vol.47 , Issue.2 , pp. 127-133
    • Dougados, M.1    Awada, H.2    Amor, B.3
  • 13
    • 0023925015 scopus 로고
    • Sensitivity of monocyte subpopulations to cyclosporine. Arachidonate metabolism and in vitro antigen presentation
    • Esa, A. H., Paxman, D. G., Noga, S. J., and Hess, A. D. (1988). Sensitivity of monocyte subpopulations to cyclosporine. Arachidonate metabolism and in vitro antigen presentation. Transplant Proc 20, 80-6.
    • (1988) Transplant Proc , vol.20 , pp. 80-86
    • Esa, A.H.1    Paxman, D.G.2    Noga, S.J.3    Hess, A.D.4
  • 14
    • 0027170712 scopus 로고
    • Cyclosporin: A review of its pharmacodynamic and pharmacokinetic properties, and therapeutic use in immunoregulatory disorders
    • Faulds, D., Goa, K. L., and Benfield, P. (1993). Cyclosporin. A review of its pharmacodynamic and pharmacokinetic properties, and therapeutic use in immunoregulatory disorders. Drugs 45, 953-1040. (Pubitemid 23219075)
    • (1993) Drugs , vol.45 , Issue.6 , pp. 953-1040
    • Faulds, D.1    Goa, K.L.2    Benfield, P.3
  • 15
    • 0028411661 scopus 로고
    • Clinical and histological evaluation of ligature-induced periodontal breakdown in domestic ferrets immunosuppressed by cyclosporin-A
    • Fischer, R. G., and Klinge, B. (1994). Clinical and histological evaluation of ligature-induced periodontal breakdown in domestic ferrets immunosuppressed by cyclosporin-A. J Clin Periodontol 21, 240-9.
    • (1994) J Clin Periodontol , vol.21 , pp. 240-249
    • Fischer, R.G.1    Klinge, B.2
  • 16
    • 0033061888 scopus 로고    scopus 로고
    • Effects of cyclosporin A on alveolar bone: An experimental study in the rat
    • DOI 10.1902/jop.1999.70.2.189
    • Fu, E., Hsieh, Y. D., Nieh, S., Wikesjo, U. M., and Liu, D. (1999). Effects of cyclosporin A on alveolar bone: an experimental study in the rat. J Periodontol 70, 189-94. (Pubitemid 29140480)
    • (1999) Journal of Periodontology , vol.70 , Issue.2 , pp. 189-194
    • Fu, E.1    Hsieh, Y.-D.2    Nieh, S.3    Wikesjo, U.M.E.4    Liu, D.5
  • 17
    • 0031152114 scopus 로고    scopus 로고
    • Cytokines and prostaglandins in immune homeostasis and tissue destruction in periodontal disease
    • Gemmell, E., Marshall, R. I., and Seymour, G. J. (1997). Cytokines and prostaglandins in immune homeostasis and tissue destruction in periodontal disease. Periodontol 2000 14, 112-43. (Pubitemid 127601173)
    • (1997) Periodontology 2000 , vol.1997 , Issue.14 , pp. 112-143
    • Gemmell, E.1    Marshall, R.I.2    Seymour, G.J.3
  • 18
    • 0142121278 scopus 로고    scopus 로고
    • Immunosuppressant therapy and bone loss in ligature-induced periodontitis - A study in rats
    • Goncalves, P. F., Filho, G. R., Sallum, E. A., Sallum, A. W., and Nociti Junior, F. H. (2003). Immunosuppressant therapy and bone loss in ligature-induced periodontitis - a study in rats. Pesqui Odontol Bras 17, 46-50.
    • (2003) Pesqui Odontol Bras , vol.17 , pp. 46-50
    • Goncalves, P.F.1    Filho, G.R.2    Sallum, E.A.3    Sallum, A.W.4    Nociti Jr., F.H.5
  • 19
    • 0141521191 scopus 로고    scopus 로고
    • Estimation of component volume and volume fraction
    • (C. V. Howard, and M. G. Reed, eds.), Chapter 4, First edition, BİOS Scientific Publishers, Oxford, UK
    • Howard, C. V., and Reed, M. G. (1998). Estimation of component volume and volume fraction. In Unbiased Stereology, Three Dimensional Measurement in Microscopy (C. V. Howard, and M. G. Reed, eds.), Chapter 4, pp. 55-68. First edition, BİOS Scientific Publishers, Oxford, UK.
    • (1998) Unbiased Stereology, Three Dimensional Measurement in Microscopy , pp. 55-68
    • Howard, C.V.1    Reed, M.G.2
  • 20
    • 0030614422 scopus 로고    scopus 로고
    • Phenytoin and cyclosporine A specifically regulate macrophage phenotype and expression of platelet-derived growth factor and interleukin-1 in vitro and in vivo: Possible molecular mechanism of drug-induced gingival hyperplasia
    • Iacopino, A. M., Doxey, D., Cutler, C. W., Nares, S., Stoever, K., Fojt, J., Gonzales, A., and Dill, R. E. (1997). Phenytoin and cyclosporine A specifically regulate macrophage phenotype and expression of platelet-derived growth factor and interleukin-1 in vitro and in vivo: possible molecular mechanism of drug-induced gingival hyperplasia. J Periodontol 68, 73-83.
    • (1997) J Periodontol , vol.68 , pp. 73-83
    • Iacopino, A.M.1    Doxey, D.2    Cutler, C.W.3    Nares, S.4    Stoever, K.5    Fojt, J.6    Gonzales, A.7    Dill, R.E.8
  • 23
    • 0023259934 scopus 로고
    • Cyclosporine: A double-edged sword
    • Keown, P. A., and Stiller, C. R. (1987). Cyclosporine: a double-edged sword. Hosp Pract 22, 219-20.
    • (1987) Hosp Pract , vol.22 , pp. 219-220
    • Keown, P.A.1    Stiller, C.R.2
  • 25
    • 0025156876 scopus 로고
    • Variation of resorption rates in vivo of various bones in immature rats
    • DOI 10.1016/0169-6009(90)90119-Z
    • Klein, L., Li, Q. X., Donovan, C. A., and Powell, A. E. (1990). Variation of resorption rates in vivo of various bones in immature rats. Bone Miner 8, 169-75. (Pubitemid 20045581)
    • (1990) Bone and Mineral , vol.8 , Issue.2 , pp. 169-175
    • Klein, L.R.1    Li, Q.X.2    Donovan, C.A.3    Powell, A.E.4
  • 26
    • 84861718720 scopus 로고    scopus 로고
    • A novel systemic field sampling approach for relatively large reference spaces used in neurostereological studies
    • Abstracts Book
    • Korkmaz, A., Ayas, B., Çiftçi, N., and Tümkaya, L. (2003). A novel systemic field sampling approach for relatively large reference spaces used in neurostereological studies. Neuroanatomy, 2 (Abstracts Book), 20P.
    • (2003) Neuroanatomy , vol.2
    • Korkmaz, A.1    Ayas, B.2    Çiftçi, N.3    Tümkaya, L.4
  • 27
    • 0025290684 scopus 로고
    • Renal side-effects of cyclosporin A
    • Mason, J. (1990). Renal side-effects of cyclosporin A. Br J Dermatol 122, 71-7.
    • (1990) Br J Dermatol , vol.122 , pp. 71-77
    • Mason, J.1
  • 28
    • 0026478860 scopus 로고
    • Effects of cyclosporin A on rat osteoblasts (ROS 17/2.8 cells) in vitro
    • McCauley, L. K., Rosol, T. J., and Capen, C. C. (1992). Effects of cyclosporin A on rat osteoblasts (ROS 17/2.8 cells) in vitro. Calcif Tissue Int 51, 291-7.
    • (1992) Calcif Tissue Int , vol.51 , pp. 291-297
    • McCauley, L.K.1    Rosol, T.J.2    Capen, C.C.3
  • 29
    • 0023708625 scopus 로고
    • Cyclosporin-A in vivo produces severe osteopenia in the rat: Effect of dose and duration of administration
    • Movsowitz, C., Epstein, S., Fallon, M., Ismail, F., and Thomas, S. (1988). Cyclosporin-A in vivo produces severe osteopenia in the rat: effect of dose and duration of administration. Endocrinology 123, 2571-7.
    • (1988) Endocrinology , vol.123 , pp. 2571-2577
    • Movsowitz, C.1    Epstein, S.2    Fallon, M.3    Ismail, F.4    Thomas, S.5
  • 32
    • 0020373795 scopus 로고
    • Characterization of the immunocompetent cells in human advanced periodontitis
    • DOI 10.1111/j.1600-0765.1982.tb02030.x
    • Okada, H., Kida, T., and Yamagami, H. (1982). Characterization of the immunocompetent cells in human advanced periodontitis. J Periodont Res 17, 472-3. (Pubitemid 13166457)
    • (1982) Journal of Periodontal Research , vol.17 , Issue.5 , pp. 472-473
    • Okada, H.1    Kida, T.2    Yamagami, H.3
  • 34
    • 0026510366 scopus 로고
    • Cyclosporin-A increases type I procollagen production and mRNA level in human gingival fibroblasts in vitro
    • Schincaglia, G. P., Forniti, F., Cavallini, R., Piva, R., Calura, G., and del Senno, L. (1992). Cyclosporin-A increases type I procollagen production and mRNA level in human gingival fibroblasts in vitro. J Oral Pathol Med 21, 181-5.
    • (1992) J Oral Pathol Med , vol.21 , pp. 181-185
    • Schincaglia, G.P.1    Forniti, F.2    Cavallini, R.3    Piva, R.4    Calura, G.5    Del Senno, L.6
  • 35
    • 0034169030 scopus 로고    scopus 로고
    • Risk factors for drug-induced gingival overgrowth
    • Seymour, R. A., Ellis, J. S., and Thomason, J. M. (2000). Risk factors for drug-induced gingival overgrowth. J Clin Periodontol 27, 217-23.
    • (2000) J Clin Periodontol , vol.27 , pp. 217-223
    • Seymour, R.A.1    Ellis, J.S.2    Thomason, J.M.3
  • 36
    • 0023443115 scopus 로고
    • The comparative effects of azathioprine and cyclosporin on some gingival health parameters of renal transplant patients. A longitudinal study
    • Seymour, R. A., Smith, D. G., and Rogers, S. R. (1987). The comparative effects of azathioprine and cyclosporin on some gingival health parameters of renal transplant patients. A longitudinal study. J Clin Periodontol 14, 610-3.
    • (1987) J Clin Periodontol , vol.14 , pp. 610-613
    • Seymour, R.A.1    Smith, D.G.2    Rogers, S.R.3
  • 37
    • 0035001065 scopus 로고    scopus 로고
    • Effects of cyclosporin A on dental alveolar bone: A histomorphometric study in rats
    • Shen, E. C., Fu, E., and Hsieh, Y. D. (2001). Effects of cyclosporin A on dental alveolar bone: a histomorphometric study in rats. J Periodontol 72, 659-65.
    • (2001) J Periodontol , vol.72 , pp. 659-665
    • Shen, E.C.1    Fu, E.2    Hsieh, Y.D.3
  • 38
    • 0028000851 scopus 로고
    • Localization of gingival overgrowth in heart transplant patients undergoing cyclosporin therapy
    • Somacarrera, M. L., Hernandez, G., Acero, J., and Moskow, B. S. (1994) Localization of gingival overgrowth in heart transplant patients undergoing cyclosporin therapy. J Periodontol 65, 666-70. (Pubitemid 24236700)
    • (1994) Journal of Periodontology , vol.65 , Issue.7 , pp. 666-670
    • Somacarrera, M.L.1    Hernandez, G.2    Acero, J.3    Moskow, B.S.4
  • 39
    • 3242811126 scopus 로고    scopus 로고
    • Effects of long-term cyclosporin therapy on the periodontium of rats
    • DOI 10.1111/j.1600-0765.2004.00734.x
    • Spolidorio, L. C., Spolidorio, D. M., and Holzhausen, M. (2004). Effects of long-term cyclosporin therapy on the periodontium of rats. J Periodontal Res 39, 257-62. (Pubitemid 38969609)
    • (2004) Journal of Periodontal Research , vol.39 , Issue.4 , pp. 257-262
    • Spolidorio, L.C.1    Spolidorio, D.M.2    Holzhausen, M.3
  • 40
    • 0020463264 scopus 로고
    • Immunosuppression and periodontal disease in man. Histological and ultrastructural observations
    • DOI 10.1111/j.1600-0765.1982.tb01162.x
    • Tollefsen, T., Koppang, H. S., and Messelt, E. (1982). Immunosuppression and periodontal disease in man. Histological and ultrastructural observations. J Periodontal Res 17, 329-44. (Pubitemid 13239270)
    • (1982) Journal of Periodontal Research , vol.17 , Issue.4 , pp. 329-344
    • Tollefsen, T.1    Koppang, H.S.2    Messelt, E.3
  • 41
    • 0022385999 scopus 로고
    • Pharmacokinetic profiles of cyclosporine in rats. Influence of route of administration and dosage
    • Wassef, R., Cohen, Z., and Langer, B. (1985). Pharmacokinetic profiles of cyclosporine in rats. Influence of route of administration and dosage. Transplantation 40, 489-93. (Pubitemid 16196198)
    • (1985) Transplantation , vol.40 , Issue.5 , pp. 489-493
    • Wassef, R.1    Cohen, Z.2    Langer, B.3
  • 42
    • 0021228976 scopus 로고
    • Characteristics of cyclosporine induction of increased prostaglandin levels from human peripheral blood monocytes
    • Whisler, R. L., Lindsey, J. A., Proctor, K. V., Morisaki, N., and Cornwell, D.G. (1984). Characteristics of cyclosporine induction of increased prostaglandin levels from human peripheral blood monocytes. Transplantation 38, 377-81. (Pubitemid 14023169)
    • (1984) Transplantation , vol.38 , Issue.4 , pp. 377-381
    • Whisler, R.L.1    Lindsey, J.A.2    Proctor, K.V.W.3


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