Diversity in neuroanatomical distribution of abnormal prion protein in atypical scrapie

PLoS Pathogens

Volumn 3, Issue 6, 2007, Pages 0743-0751

  Nentwig, Alice ^a   Oevermann, Anna ^a   Heim, Dagmar ^b   Botteron, Catherine ^a   Zellweger, Karola ^a   Drögemüller, Cord ^a   Zurbriggen, Andreas ^a   Seuberlich, Torsten ^a  

^a UNIVERSITY OF BERN   (Switzerland)

^b SWISS FEDERAL VETERINARY OFFICE   (Switzerland)

Author keywords

[No Author keywords available]

Indexed keywords

PRION PROTEIN; PROTEINASE K;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BIODIVERSITY; CONTROLLED STUDY; ELECTROPHORETIC MOBILITY; GENOTYPE; GOAT; IMMUNOHISTOCHEMISTRY; MORPHOLOGICAL TRAIT; NEUROANATOMY; NEUROPATHOLOGY; NONHUMAN; NUCLEOTIDE SEQUENCE; PHENOTYPE; PRION DISEASE; SCRAPIE; SHEEP; WESTERN BLOTTING; AMINO ACID SEQUENCE; ANIMAL; BRAIN; ENZYME IMMUNOASSAY; GENETIC VARIABILITY; GENETICS; GOAT DISEASE; METABOLISM; MOLECULAR GENETICS; PATHOLOGY;

CAPRA HIRCUS; OVIS ARIES;

AMINO ACID SEQUENCE; ANIMALS; BLOTTING, WESTERN; BRAIN; GOAT DISEASES; GOATS; IMMUNOENZYME TECHNIQUES; MOLECULAR SEQUENCE DATA; PRPSC PROTEINS; SCRAPIE; SHEEP; VARIATION (GENETICS);

EID: 34347337685     PISSN: 15537366     EISSN: 15537374     Source Type: Journal    
DOI: 10.1371/journal.ppat.0030082     Document Type: Article

References (23)

1. Prusiner SB (1982) Novel proteinaceous infectious particles cause scrapie. Science 216: 136-144.
2. Foster JD, Parnham DW, Hunter N, Bruce M (2001) Distribution of the prion protein in sheep terminally affected with BSE following experimental oral transmission. J Gen Virol 82: 2319-2326.
3. Houston F, Foster JD, Chong A, Hunter N, Bostock CJ (2000) Transmission of BSE by blood transfusion in sheep. Lancet 356: 999-1000.
4. Eloit M, Adjou K, Coulpier M, Fontaine JJ, Hamel R, et al. (2005) BSE agent signatures in a goat. Vet Rec 156: 523-524.
5. Benestad SL, Sarradin P, Thu B, Schonheit J, Tranulis MA, et al. (2003) Cases of scrapie with unusual features in Norway and designation of a new type, Nor98. Vet Rec 153: 202-208.
6. Baron T, Biacabe AG, Arsac JN, Benestad S, Groschup MH (2006) Atypical transmissible spongiform encephalopathies (TSEs) in ruminants. Vaccine. E-pub 13 November 2006.
7. Buschmann A, Biacabe AG, Ziegler U, Bencsik A, Madec JY, et al. (2004) Atypical scrapie cases in Germany and France are identified by discrepant reaction patterns in BSE rapid tests. J Virol Methods 117: 27-36.
8. European Food Safety Authority (2005) Opinion of the scientific panel on biological hazards on the request from the European Commission on classification of atypical transmissible spongiform encephalopathy (TSE) cases in small ruminants. EFSA J 276: 1-30.
9. Seuberlich T, Botteron C, Benestad SL, Brünisholz H, Wyss R, et al. (2007) Atypical scrapie in a Swiss goat and implications for transmissible spongiform encephalopathy surveillance. J Vet Diagn Invest 19: 2-8.
10. Gretzschel A, Buschmann A, Langeveld J, Groschup MH (2006) Immunological characterization of abnormal prion protein from atypical scrapie cases in sheep using a panel of monoclonal antibodies. J Gen Virol 87: 3715-3722.
11. Klingeborn M, Wik L, Simonsson M, Renstrom LH, Ottinger T, et al. (2006) Characterization of proteinase K-resistant N- and C-terminally truncated PrP in Nor98 atypical scrapie. J Gen Virol 87: 1751-1760.
12. Arsac JN, Andreoletti O, Bilheude JM, Lacroux C, Benestad SL, et al. (2007) Similar biochemical signatures and prion protein genotypes in atypical scrapie and Nor98 cases, France and Norway. Emerg Infect Dis 13: 58-65.
13. Onnasch H, Gunn HM, Bradshaw BJ, Benestad SL, Bassett HF (2004) Two Irish cases of scrapie resembling Nor98. Vet Rec 155: 636-637.
14. Gavier-Widen D, Noremark M, Benestad S, Simmons M, Renstrom L, et al. (2004) Recognition of the Nor98 variant of scrapie in the Swedish sheep population. J Vet Diagn Invest 16: 562-567.
15. Buschmann A, Luhken G, Schultz J, Erhardt G, Groschup MH (2004) Neuronal accumulation of abnormal prion protein in sheep carrying a scrapie-resistant genotype (PrPARR/ARR). J Gen Virol 85: 2727-2733.
16. Schoch G, Seeger H, Bogousslavsky J, Tolnay M, Janzer RC, et al. (2006) Analysis of prion strains by PrPSc profiling in sporadic Creutzfeldt-Jakob disease. PLoS Med 3: e14. doi:10.1371/journal.pmed.0030014
17. Moum T, Olsaker I, Hopp P, Moldal T, Valheim M, et al. (2005) Polymorphisms at codons 141 and 154 in the ovine prion protein gene are associated with scrapie Nor98 cases. J Gen Virol 86: 231-235.
18. Luhken G, Buschmann A, Brandt H, Eiden M, Groschup MH, et al. (2007) Epidemiological and genetical differences between classical and atypical scrapie cases. Vet Res 38: 65-80.
19. Tagliavini F, Prelli F, Porro M, Rossi G, Giaccone G, et al. (1994) Amyloid fibrils in Gerstmann-Straussler-Scheinker disease (Indiana and Swedish kindreds) express only PrP peptides encoded by the mutant allele. Cell 79: 695-703.
20. Tagliavini F, Lievens PM, Tranchant C, Warter JM, Mohr M, et al. (2001) A 7-kDa prion protein (PrP) fragment, an integral component of the PrP region required for infectivity, is the major amyloid protein in Gerstmann-Straussler- Scheinker disease A117V. J Biol Chem 276: 6009-6015.
21. Kitamoto T, Amano N, Terao Y, Nakazato Y, Isshiki T, et al. (1993) A new inherited prion disease (PrP-P105L mutation) showing spastic paraparesis. Ann Neurol 34: 808-813.
22. Collins S, McLean CA, Masters CL (2001) Gerstmann-Straussler-Scheinker syndrome, fatal familial insomnia, and kuru: A review of these less common human transmissible spongiform encephalopathies. J Clin Neurosci 8: 387-397.
23. Le Dur A, Beringue V, Andreoletti O, Reine F, Lai TL, et al. (2005) A newly identified type of scrapie agent can naturally infect sheep with resistant PrP genotypes. Proc Natl Acad Sci U S A 102: 16031-16036.