Risk factors of local relapse in breast cancer: The importance of age

Clinical and Translational Oncology

Volumn 9, Issue 2, 2007, Pages 110-116

  Algara Lopez M ^a,b   Sanz Latiesas, X ^a   Foro Arnalot, P ^a   Lacruz Bassols, M ^a   Reig Castillejo, A ^a   Quera Jordana, J ^a   Membrive Conejo, I ^a   Lozano Galan J ^a   Rodriguez de Dios N ^a  

^a HOSPITAL DE L ESPERANÇA   (Spain)

^b UNIVERSITAT POMPEU FABRA   (Spain)

Author keywords

Age; Breast cancer; Conservative treatment; Radiotherapy; Risk factors

Indexed keywords

ANTHRACYCLINE; TAMOXIFEN;

ADULT; AGE; ARTICLE; BREAST CANCER; CANCER HORMONE THERAPY; CANCER RECURRENCE; CANCER RELAPSE; CANCER SURVIVAL; COMORBIDITY; DISEASE FREE SURVIVAL; FEMALE; FOLLOW UP; HUMAN; INTRADUCTAL CARCINOMA; IRRADIATION; MAJOR CLINICAL STUDY; MASTECTOMY; METASTASIS; RADIATION DERMATITIS; RADIATION DOSE; RADIATION DYSPHAGIA; RADIATION INJURY; RADIATION PNEUMONIA; RADIATION SARCOMA; RADIATION SKIN FIBROSIS; RISK FACTOR; SURVIVAL RATE; TUMOR VOLUME; ADENOCARCINOMA; BREAST TUMOR; MIDDLE AGED; TUMOR RECURRENCE;

ADENOCARCINOMA; AGE FACTORS; BREAST NEOPLASMS; FEMALE; FOLLOW-UP STUDIES; HUMANS; MIDDLE AGED; NEOPLASM RECURRENCE, LOCAL; RISK FACTORS;

EID: 34347230961     PISSN: 1699048X     EISSN: None     Source Type: Journal    
DOI: 10.1007/s12094-007-0021-8     Document Type: Article

References (66)

1. Guix B, Guix R, Lejárcegui JA et al (1987) Tratamiento conservador de los estadios I y II del cáncer de mama mediante cirugia limitada e irradiación con sobreimpresión del lecho tumoral mediante iridio-192. Experiencia en 92 pacientes controladas durante 4 años. Med Clin (Barc) 88:481-485
2. Fernández-Cid A (1989) Tratamiento conservador del cáncer de mama. Med Clin (Barc) 93: 611-612
3. Mena A, García A, Moreno I et al (2006) Conservative treatment for infiltrating breast cancer: Ten years follow-up experience. Clin Transl Oncol 8:672-675
4. Fisher B, Bauer M, Margolese R et al (1985) Five-year results of a randomized clinical trial comparing total mastectomy and segmental mastectomy with or whithout radiation in the treatment of breast cancer. N Engl J Med 312: 665-673
5. Veronesi U, Zucali R, Luini A (1986) Local control and survival in early breast cancer: The Milan trial. Int J Radiat Oncol Biol Phys 12: 717-720
6. Barnadas A (1995) E¿s posible la curación del cancer de mama? Med Clin (Barc) 105:738-739
7. Veronesi U, Cascinelli N, Luigi M et al (2002) Twenty-year follow-up of a randomized study comparing breast-conserving surgery with radical mastectomy for early breast cancer. N Engl J Med 347:1227-1232
8. Fisher B, Anderson S, Bryant J et al (2002) Twenty-year follow-up of a randomized study comparing total mastectomy, lumpectomy, and lumpectomy plus irradiation for the treatment of invasive breast cancer. N Engl J Med 347:1233-1241
9. Arenas M, Sabater S, Hernández V et al (2006) Cosmetic outcome of breast conservative treatment for early stage breast cancer. Clin Tansl Oncol 8:334-338
10. Recht A, Connolly JL, Schnitt SJ et al (1988) The effect of young age on tumour recurrence in the treated breast after conservative surgery and radiotherapy. Int J Radiat Oncol Biol Phys 14: 3-10
11. Boyages J, Recht A, Connolly JL et al (1990) Early breast cancer: Predictors of breast recurrence for patients treated with conservative surgery and radiation therapy. Radiother Oncol 19: 29-41
12. Halverson KJ, Perez C, Taylor ME et al (1993) Age as a prognostic factor for breast and regional nodal recurence following breast conserving surgery and irradiation in stage I and II breast cancer. Int J Radiat Oncol Biol Phys 27: 1045-1050
13. Slotman BJ, Meyer OWM, Njo KH, Karim ABMF (1994) Importance of timming of radiotherapy in breast conserving treatment for early stage breast cancer. Radiother Oncol 30:206-212
14. Albanell J, Bellmunt J, Sole LA (1992) Factores pronósticos del cáncer de mama con ganglios negativos. Med Clin (Barc) 99:668-674
15. Bartelink H, Borger JH, van Dongen JA, Peterse JL (1988) The impact of tumour size and histology on local control after breast-conserving therapy. Radiother Oncol 11:297-303
16. Veronesi U, Salvadori B, Luini A et al (1995) Breast conservation is a safe method in patients with small cancer of the breast. Long-term results of three randomised trials on 1973 patients. Eur J Cancer 31A:1574-1579
17. Paterson DA, Anderson TJ, Lack WJ et al (1992) Pathological features predictive of local recurrence after management by conservation of invasive breast cancer: Importance of non-invasive carcinoma. Radiother Oncol 25:176-180
18. Moreno F, Guedea F, López Y et al (2000) External beam irradiation plus 192Ir implant after breast-preserving surgery in women with early breast cancer. Int J Radiat Oncol Biol Phys 48:757-765
19. Bartelink H, Horiot JC, Poortmans P et al (2001) Recurrence rates after tratment of breast cancer with standard radiotherapy with or whitout aditional radiation. N Engl J Med 345:1378-1387
20. Bellon JR, Harris JR (2005) What extent of radiation therapy is standard? Breast 14:532-540
21. Marrugat J, Sanz F, Algara M, Valls A (1994) Metodología de los ensayos en radioterapia. In: En Sanchiz F, Millá A, Valls A (eds) Tratado de radioterapia oncológica, 1st Edn. Espaxs, Barcelona, pp 147-161
22. Sachs L (1978) Applied statistics: A handbook of techniques. Springer-Verlag, New York
23. Kaplan EL, Meier P (1958) Non-parametric estimation from incomplete observations. J Am Statist Assoc 53:458-481
24. Armitage P, Bery G (1992) Estadística para la investigación biomédica, 1st Edn. Ediciones Doyma, Barcelona, pp 491-515
25. Fredriksson I, Liljegren G, Arnesson LG et al (2002) Local recurrence in the breast after conservative surgery - a study of prognosis and prognostic factors in 391 women. Eur J Cancer 38:1860-1870
26. Fortin A, Larochelle M, Laverdière J et al (1999) Local failure is responsible for the decrease in survival for patients with breast cancer treated with conservative surgery and postoperative radiotherapy. J Clin Oncol 17:101-109
27. Sasson A, Fowble B, Hanlon AL et al (2001) Lobular carcinoma in situ increases the risk of local recurrence in selected patients with stages I and II breast carcinoma treated with conservative surgery and radiation. Cancer 91:1862-1869
28. Algara M, Valls A, Foro P et al (1999) Control local y resultado estético en el tratamiento conservador del cáncer de mama. Analisis de 397 casos consecutivos. Rev Clin Esp 199:18-24
29. Kurtz JM, Spitalier JM, Amalric R et al (1988) Mammary recurrence in women younger than forty. Int J Radiat Oncol Biol Phys 15:271-276
30. Solin LJ, Fowble B, Martz KL, Goodman RL (1988) Definitive irradiation for early stage breast cancer: The University of Pennsylvania experience. Int J Radiat Oncol Biol Phys 14:235- 242
31. Burke MF, Allison R, Obst D, Tripcony L (1994) Conservative therapy of breast cancer in Queensland. Int J Radiat Oncol Biol Phys 31: 295-303
32. Navarro JF, Vioque J, Cuchí C et al (1995) Supervivencia del cancer de mama en Zaragoza (1960-1990) en relacion con la edad, estadio clonico y periodo del tiempo del diagnostico. Med Clin (Barc) 105:721-727
33. Kodaira T, Fuwa N, Itoh Y et al (2001) Aichi cancer center 10-year experience with conservative breast treatment of early breast cancer: retrospective analysis regarding failure patterns and factors influencing local control. Int J Radiat Oncol Biol Phys 49:1311-1316
34. Medina-Franco H, Beenken SW, Heslin MJ et al (2003) Local recurrence after breast conserving therapy for invasive breast cancer: Analysis of prognostic factors. Rev Oncol 5:93-97
35. Leborgne F, Leborgne JH, Ortega B et al (1995) Breast conservation treatment of early stage breast cancer: Patterns of failure. Int J Radiat Oncol Biol Phys 31:765-775
36. Freedman GM, Hanlon AL, Fowble BL et al (2002) Recursive partitioning identifies patients at high and low risk for ipsilateral tumor recurrence after breast-conserving surgery and radiation. J Clin Oncol 20:4015-4021
37. Cefaro GA, Genovesi D, Marchese R et al (2006) Predictors of local recurrence after conservative surgery and whole-breast irradiation. Breast Cancer Res Treat 98:329-335
38. Fowble B, Schultz D, Overmoyer B et al (1994) The influence of young age on otcome in early breast cancer. Int J Radiat Oncol Biol Phys 30: 23-33
39. Arraigada R, Lê MG, Contesso G et al (2002) Predictive factors for local recurrence in 2006 patients with surgically resected small breast cancer. Ann Oncol 13:1404-1413
40. Voogd AC, Nielsen M, Peterse JL et al (2001) Differences in risk factors for local and distant recurrence after brast-conserving therapy or mastectomy for stage I and II breast cancer: Pooled results of two large European randomized trials. J Clin Oncol 19:1688-1697
41. Fowble BL, Schultz DJ, Overmoyer B et al (1994) The influence of young age on outcome in early stage breast cancer. Int J Radiat Oncol Biol Phys 30:23-33
42. Jobsen JJ, van der Palen J, Meerwaldt JH (2001) The impact of age on local control in women with pT1 breast cancer treated with conservative surgery and radiation therapy. Eur J Cancer 37: 1820-1827
43. Arriagada R, Lê MG, Rochard F, Contesso G (1996) Conservative treatment versus mastectomy in early breast cancer: Patterns of failure with 15 years of follow-up data. J Clin Oncol 14:1558-1564
44. Gamel JW, Meyer JS, Feuer E et al (1996) The impact of stage and histology on the long-term clinical course of 163.808 patients with breast carcinoma. Cancer 77:459-464
45. Harris JR, Connolly JL, Schnitt SJ et al (1985) The use of pathological features in selecting the extent of surgical resection necessary for breast cancer patients treated by primary radiation therapy. Ann Surg 201:164-169
46. Fourquet A, Campana F, Zafrani B et al (1989) Prognostic factors of breast recurrence in the conservative management of early breast cancer: a 25-year follow-up. Int J Radiat Oncol Biol Phys 17:719-725
47. Fisher ER, Sass R, Fisher B et al (1986) Pathologic findings from the National Surgical Adjuvant Breast Project (protocol 6): II. Relation of local breast recurrence to multicentricity. Cancer 57:1717-1724
48. Biijker N, Peterse JL, Duchateau L et al (2001) Risk factors for recurrence and metastasis after breast-conserving therapy for ductal carcinoma in situ; analysis of EORTC trial 10853. J Clin Oncol 19:2263-2271
49. Jobsen JJ, Van der Palen J, Ong F et al (2003) The value of a positive margin for invasive carcinoma in breast-conservative treatment in relation to local recurrence is limited to young women only. Int J Radiat Oncol Biol Phys 57: 724-731
50. Fowble B (1994) The relationship between local relapse and distant metastases revisited. Int J Radiat Oncol Biol Phys 30:237-239
51. Solin LJ, Fowble B, Martz K et al (1986) Results of the re-excisional biopsy of the primary tumor in preparation for definitive irradiation of patients with early stage breast cancer. Int J Radiat Oncol Biol Phys 12:721-725
52. Freedman G, Fowble B, Hanlon A et al (1999) Patients with early stage invasive cancer with close or positive margins treated with conservative surgery and radiation have an increased risk of breast recurrence that is delayed by adjuvant systemic therapy. Int J Radiat Oncol Biol Phys 44:1005-1105
53. Herruzo AJ, Rodríguez A (1997) Margenes quirúrgicos y componente intraductal en el tratamiento conservador del cáncer de mama. Folia Clin Obstet Ginecol 3:35-40
54. Clarke DH, Martínez AA (1992) Identification of patients who are at high risk for locoregional breast cancer recurrence after conservative surgery and radiotherapy: A review article for surgeons, pathologist, and radiation and medical oncologist. J Clin Oncol 10:474-483
55. Swanson GP, Rynerson K, Symmonds R (2002) Significance of margins of excision on breast cancer recurrence. Am J Clin Oncol 25:438-441
56. Sierra A, Fernández F, González J et al (1997) Tratamiento conservador del cáncer de mama. Estudio sobre 284 casos. Revista de senología y paología mamaria 10:20-26
57. Sans-Sabrafén J (1987) Tratamiento del cáncer de mama. Med Clin (Barc) 88:497-499
58. Algara M, Segura M, Sanz X et al (2001) Rentabilidad de la ampliación de márgenes en cirugía conservadora de la neoplasia de mama. Revista de Oncologǐa 3[Suppl 1]:59
59. Recht A, Come SE, Henderson C et al (1996) The sequencing of chemotherapy and radiation therapy after conservative surgery for early-stage breast-cancer. N Engl J Med 334:1356- 1361
60. Nixon AJ, Recht A, Neuberg D et al (1994) The relation between the surgery-radiotherapy interval and treatment outcome in patients treated with breast-conserving surgery and radiation therapy without systemic therapy. Int J Radiat Oncol Biol Phys 30:17-21
61. Vujovic O, Perera F, Dar AR et al (1998) Does delay in breast irradiation the following conservative breast surgery in node-negative breast cancer patients have an impact on risk of recurrence. Int J Radiat Oncol Biol Phys 40:869-874
62. Buchholz TA, Austin-Seymour MM, Moe RE et al (1993) Effect of delay in radiation in the combined modality treatment of breast cancer. Int J Radiat Oncol Biol Phys 26:23-35
63. Solin LJ, Fowble BL, Schultz DJ, Goodman RL (1991) The significance of the pathology margins of the tumor excision on the outcome of patients treated with definitive irradiation for early breast cancer. Int J Radiat Oncol Biol Phys 21: 279-287
64. Schmidt-Ullrich RK, Wazer DE, DiPetrillo T et al (1993) Breast conservation therapy for early stage breast carcinoma with outstanding 10-year locoregional control rates: A case for agressive therapy to the tumor bearing cuadrant. Int J Radiat Oncol Biol Phys 27:545-552
65. Kemperman H, Borger J, Hart A et al (1995) Prognostic factors for survival after breast conserving therapy for stage I and II breast cancer. The role of local recurrence. Eur J Cancer 31A: 690-698
66. Recht A (1993) When is more better. Int J Radiat Oncol Biol Phys 27:749-751