Local control and aesthetic outcome with the conservative treatment of breast cancer. Analysis of 397 consecutive cases;Control local y resultado estético en el tratamiento conservador del cáncer de mama. Análisis de 397 casos consecutivos

Revista Clinica Espanola

Volumn 199, Issue 1, 1999, Pages 18-24

  López, M Algara ^a   Fontanals, A Valls ^a   Arnalot, P Foro ^a   Castillejo, A Reig ^a   Bassols, M Lacruz ^a  

^a NONE

Author keywords

Aesthetic result; Breast cancer; Conservative therapy; Local control

Indexed keywords

ADJUVANT THERAPY; ADOLESCENT; ADULT; AGED; ARTICLE; BREAST TUMOR; CANCER STAGING; DISEASE FREE SURVIVAL; ESTHETICS; FEMALE; HUMAN; MASTECTOMY; MIDDLE AGED; MORTALITY; PATHOLOGY; RADIATION DOSE; RISK FACTOR; SURVIVAL; TUMOR RECURRENCE;

ADOLESCENT; ADULT; AGED; BREAST NEOPLASMS; DISEASE-FREE SURVIVAL; ESTHETICS; FEMALE; HUMANS; MASTECTOMY; MIDDLE AGED; NEOPLASM RECURRENCE, LOCAL; NEOPLASM STAGING; RADIOTHERAPY DOSAGE; RADIOTHERAPY, ADJUVANT; RISK FACTORS; SURVIVAL ANALYSIS;

EID: 0039613878     PISSN: 00142565     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (63)

1. Guix B, Guix R, Lejárcegui JA, Bule C, Viñas E, Guix JR. Tratamiento conservador de los estadios I y II del cáncer de mama mediante cirugía limitada e irradiación con sobreimpresión del lecho tumoral mediante iridio-192. Experiencia en 92 pacientes controladas durante 4 años. Med Clín (Barc) 1987; 88:481-485.
2. Fernández-Cid A. Tratamiento conservador del cáncer de mama. Med Clín (Barc) 1989; 93:611-612.
3. Fisher B, Bauer M, Margolese R, et al. Five-years results of a randomized clinical trial comparing total mastectomy and segmental mastectomy with or whithout radiation in the treatment of breast cancer. New Eng J Med 1985; 312(11):665-673.
4. Veronesi U, Zucali R, Luini A. Local control and survival in early breast cancer: the Milan trial. Int J Radiat Oncol Biol Phys 1986; 12:717-720.
5. Barnadas A. ¿Es posible la curación del cancer de mama? Med Clín (Barc) 1995; 105(19): 738-739.
6. Biete A. Papel actual de la radioterapia en el cáncer de mama. Med Clín (Barc) 1989; 93:616-624.
7. Hammer J, Seewald DH, Track C, Zoidi JP, Labeck W. Breast cancer: primary treatment with external-beam radiation therapy and high-dose-rate iridium implantation. Radiology 1994; 193:573-577.
8. Wazer DE, Kramer B, Schmid C, Ruthazer R, Ulin K, Schmidt-Ullrich R. Factors determining outcome in patients treated with interstitial implantation as a radiation boost for breast conservation therapy. Int J Radiat Oncol Biol Phys 1997; 39:331-393.
9. Touboul E, Belkacemi Y, Lefranc JP, et al. Early breast cancer: influence of type of boost (electrons vs iridium-192 implant) on local control and cosmesis after conservative surgery and radiation therapy. Radiother Oncol 1995; 34:105-113.
10. Pérez CA, Taylor ME, Halverson K, García D, Kuske RR, Lockett MA. Brachytherapy or electron beam boost in conservation therapy of carcinoma of the breast: a nonrandomized comparison. Int J Radiat Oncol Biol Phys 1996; 34(5):995-1.007.
11. Leborgne F, Leborgne JH, Ortega B, Doldan R, Zubizarreta E. Breast conservation treatment of early breast cancer: patterns of failure. Int J Radiat Oncol Biol Phys 1995; 31:765-775.
12. Kurtz JM. Radiotherapy in the curative treatment of breast cancer: current status and future trends. Radiother Oncol 1994; 32:21-28.
13. Recht A, Connolly JL, Schnitt SJ, et al. The effect of young age on tumour recurrence in the treated breast after conservative surgery and radiotherapy. Int J Radiat Oncol Biol Phys 1988; 14:3-10.
14. Boyages J, Recht A, Connolly JL, et al. Early breast cancer: predictors of breast recurrence for patients treated with conservative surgery and radiation therapy. Radiother Oncol 1990; 19:29-41.
15. Halverson KJ, Pérez C, Taylor ME, et al. Age as a prognostic factor for breast and regional nodal recurence following breast conserving surgery and irradiation in stage I and II breast cancer. Int J Radiat Oncol Biol Phys 1993; 27:1.045-1.050.
16. Slotman BJ, Meyer OWM, Njo KH, Karim ABMF. Importance of timming of radiotherapy in breast conserving treatment for early stage breast cancer. Radiother Oncol 1994; 30:206-212.
17. Albanell J, Bellmunt J, Sole LA. Factores pronósticos del cáncer de mama con ganglios negativos. Med Clín (Barc) 1992; 99(17):668-674.
18. Bartelink H, Borger JH, Van Dongen JA y Peterse JL. The impact of tumour size and histology on local control after breast-conserving therapy. Radiother Oncol 1988; 11:297-303.
19. Veronesi U, Salvadori B, Luini A, et al. Breast conservation is a safe method in patients with small cancer of the breast. Long-term results of three randomised trials on 1973 patients. Eur J Cancer 1995; 31A(10): 1.574-1.579.
20. Paterson DA, Anderson TJ, Lack WJ, Kerr GR, Rodger A, Chetty U. Pathological features predictive of local recurrence after management by conservation of invasive breast cancer: importance of non-invasive carcinoma. Radiother Oncol 1992; 25:176-180.
21. Veronesi U, Banfi A, Salvadori B, et al. Breast conservation is the treatment of choice in small breast cancer: long-term results of a randomized trial. Eur J Cancer 1990; 26(6):668-670.
22. Van Limbergen E, Van der Schueren E, van den Bogaert W, Van Wing J. Local control of operable breast cancer after radiotherapy alone. Eur J Cancer 1990; 26(6):674-679.
23. Arriagada R, Mouriesse H, Rezvani A, et al. Radiotherapy alone in breast cancer. Analysis of tumour and lymph node radiation doses and treatment-related complications. Radiother Oncol 1993; 27:1-6.
24. Fourquet A, Campana F, Mosseri V, et al. Iridium-192 versus cobalt-60 boost in 3-7 cm breast cancer treated by irradiation alone: final results of a randomized trial. Radiother Oncol 1995; 34:114-120.
25. Hartsell WF, Recine DC, Griem KL, Cobleigh MA, Witt TR, Murthy AK. Should multicentric disease be an absolute contraindication to the use of breast-conserving therapy ? Int J Radiat Oncol Biol Phys 1994; 30:49-53.
26. Fung MC, Schultz DJ, Solin LJ. Early-satge bilateral breast treated with breast-conserving surgery and definitive irradiation: the university of Pennsylvania experience. Int J Radiat Oncol Biol Phys 1997; 38:959-967.
27. o ed). Barcelona: Espaxs, 1994:147-161.
28. Sachs L. Applied statistics: a handbook of techniques. New York: Springer-Verlag, 1978.
29. Everitt BS. The analysis of contingency tables. London: Chapman and Hall, 1977.
30. Matthews DE, Farewell VT. Using and understanding Medical Statistics. Second revised edition. Basel: Karger, 1988.
31. Kaplan EL, Meier P. Non-parametric estimation from incomplete observations. J Am Statist Assoc 1958; 53:458-481.
32. o ed). Barcelona. Ediciones Doyma, 1992: 491-515.
33. Statistical Package for Social Sciences (3rd ed). Chicago: SPSS Inc, 1988.
34. Dixon WJ, Brown MB, Engelman L. BMDP statistical software 1981. Berkeley: University of California Press, 1981.
35. Solin LJ, Fowble B, Martz KL, Goodman RL. Definitive irradiation for early stage breast cancer: the University of Pennsylvania experience. Int J Radiat Oncol Biol Phys 1988; 14:235-242.
36. Burke MF, Allison R, Obst D, Tripcony L. Conservative therapy of breast cancer in Queensland. Int J Radiat Oncol Biol Phys 1994; 31(2):295-303.
37. Navarro JF, Vioque J, Cuchí C, et al. Supervivencia del cáncer de mama en Zaragoza (1960-1990) en relación con la edad, estadio clínico y período del tiempo del diagnóstico. Med Clín (Barc 1995; 105(19):721-727.
38. Borger JH, Kemperman H, Smitt HS, et al. Dose and volume effects on fibrosis after breast conservation therapy. Int J Radiat Oncol Biol Phys 1994; 30:1.073-1.081.
39. Taylor ME, Pérez C, Halverson KJ, et al. Factors influencing cosmetic results after conservation therapy for breast cancer. Int J Radiat Oncol Biol Phys 1995; 31(4):753-764.
40. Moody AM, Mayles WPM, Bliss JM, et al. The influence of breast size on late radiation effects and association with radiotherapy dose inhomogeneity. Radiother Oncol 1994; 33:106-112.
41. Lichter AS. Lumpectomy and radiation: improving the outcome. J Clin Oncol 1992; 10(3):349-351.
42. Fagundes MA, Fagundes HM, Brito CS. Breast-conserving surgery and definitive radiation: a comparison between quadrantectomy and local excision with special focus on local-regional control cosmesis. Int J Radiat Oncol Biol Phys 1993; 27:553-560.
43. Fisher B. Lumpectomy versus quadrantectomy for breast conservation: a critical appraisal. Eur J Cancer 1995; 31A(10):1.567-1.569.
44. Sacchini V, Luini A, Agresti R, et al. The influence of radiotherapy on cosmetic outcome after breast conservative surgery. Int J Radiat Oncol Biol Phys 1995; 33:59-64.
45. Sacchini V, Ferreri AJM, Farante G, et al. Efecto de la radioterapia sobre los resultados estéticos del tratamiento conservador del cáncer de mama. Oncologia 1994; 17(10):427-433.
46. Fowble BL, Schultz DJ, Overmoyer B, et al. The influence of young age on outcome in early stage breast cancer. Int J Radiat Oncol Biol Phys 1994; 30:23-33.
47. Fowble B. The relationship between local relapse and distant metastases revisited. Int J Radiat Oncol Biol Phys 1994; 30:237-239.
48. Solin LJ, Fowble B, Martz K, Pajak TF, Goodman RL. Results of the re-excisional biopsy of the primary tumor in preparation for definitive irradiation of patients with early stage breast cancer. Int J Radiat Oncol Biol Phys 1986; 12:721-725.
49. Sierra A, Fernández F, González J, et al. Tratamiento conservador del cancer de mama. Estudio sobre 284 casos. Revista de Senología y Patología Mamaria 1997; 10(1):20-26.
50. Sans-Sabrafén J. Tratamiento del cancer de mama. Med Clín (Barc) 1987; 88:497-499.
51. Herruzo AJ, Rodríguez A. Márgenes quirúrgicos y componente intraductal en el tratamiento conservador del cancer de mama. Folia Clinica en Obstetricia y Ginecología 1997; 3:35-40.
52. Clarke DH, Martínez AA. Identification of patients who are at high risk for locoregional breast cancer recurrence after conservative surgery and radiotherapy: a review article for surgeons, pathologist, and radiation and medical oncologist. J Clin Oncol 1992; 10:474-483.
53. Solin LJ, Fowble BL, Schultz DJ, Goodman RL. The significance of the pathology margins of the tumor excision on the outcome of patients treated with definitive irradiation for early breast cancer. Int J Radiat Oncol Biol Phys 1991; 21:279-287.
54. Schmidt-Ullrich RK, Wazer DE, DiPetrillo T, et al. Breast conservation therapy for early stage breast carcinoma with outstanding 10-year locoregional control rates: a case for agressive therapy to the tumor bearing cuadrant. Int J Radial Oncol Biol Phys 1993; 27:545-552.
55. Kemperman H, Borger J, Hart A, Peterse H, Bartelink H, Van Dongen J. Prognostic factors for survival after breast conserving therapy for stage I and II breast cancer. The role of local recurrence. Eur J Cancer 1995; 31A(5):690-698.
56. Recht A. When is more better. Int J Radiat Oncol Biol Phys 1993; 27:749-751.
57. Kurtz JM, Spitalier JM, Amalric R J, et al. The prognostic significance of late local recurrence after breast-conserving therapy. Int J Radiat Oncol Biol Phys 1990; 18:87-93.
58. Kurtz JM, Amalric R, Delouche G, Pierquin B, Roth J, Spitalier JM. The second ten years: long-term risks of breast conservation in early breast cancer. Int J Radiat Oncol Biol Phys 1987; 13:1.327-1.332.
59. Nobler MP, Venet L. Prognostic factors in patients undergoing curative irradiation for breast cancer. Int J Radiat Oncol Biol Phys 1985; 11:1.323-1.331.
60. Levitt S. Primary treatment of early breast cancer with conservation surgery and radiation therapy. Cancer 1985; 55:2.140-2.148.
61. Recht A, Come SE, Henderson C, et al. The sequencing of chemotherapy and radiation therapy after conservative surgery for early-stage breast-cancer. N Engl J Med 1996; 334:1.356-1.361.
62. Nixon AJ, Recht A, Neuberg D, et al. The relation between the surgery-radiotherapy interval and treatment outcome in patients treated with breast-conserving surgery and radiation therapy without systemic therapy. Int J Radiat Oncol Biol Phys 1994; 30:17-21.
63. Buchholz TA, Austin-Seymour MM, Moe RE, et al. Effect of delay in radiation in the combined modality treatment of breast cancer. Int J Radiat Oncol Biol Phys 1993; 26:23-35.