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Volumn 120, Issue 1, 2007, Pages 79-84

Effect of free fatty acid inhibition on silent and symptomatic myocardial ischemia in diabetic patients with coronary artery disease

Author keywords

Diabetes mellitus; Myocardial ischema; Prognosis; Therapy

Indexed keywords

FATTY ACID; GLYCOSYLATED HEMOGLOBIN; PLACEBO; TRIMETAZIDINE;

EID: 34347215790     PISSN: 01675273     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ijcard.2006.08.082     Document Type: Article
Times cited : (42)

References (43)
  • 1
    • 0031752685 scopus 로고    scopus 로고
    • Global burden of diabetes, 1995-2025: prevalence, numerical estimates, and projections
    • King H., Aubert R.E., and Herman W.H. Global burden of diabetes, 1995-2025: prevalence, numerical estimates, and projections. Diabetes Care 21 9 (Sep 1998) 1414-1431
    • (1998) Diabetes Care , vol.21 , Issue.9 , pp. 1414-1431
    • King, H.1    Aubert, R.E.2    Herman, W.H.3
  • 2
    • 0027406191 scopus 로고
    • Diabetes, other risk factors, and 12-yr cardiovascular mortality for men screened in the Multiple Risk Factor Intervention Trial
    • Stamler J., Vaccaro O., Neaton J.D., and Wentworth D. Diabetes, other risk factors, and 12-yr cardiovascular mortality for men screened in the Multiple Risk Factor Intervention Trial. Diabetes Care 16 (1993) 434-444
    • (1993) Diabetes Care , vol.16 , pp. 434-444
    • Stamler, J.1    Vaccaro, O.2    Neaton, J.D.3    Wentworth, D.4
  • 3
    • 0037903801 scopus 로고    scopus 로고
    • Impact of diabetes on mortality after the first myocardial infarction. The FINMONICA Myocardial Infarction Register Study Group
    • Miettinen H., Lehto S., Salomaa V., et al. Impact of diabetes on mortality after the first myocardial infarction. The FINMONICA Myocardial Infarction Register Study Group. Diabetes Care 21 (1998) 69-75
    • (1998) Diabetes Care , vol.21 , pp. 69-75
    • Miettinen, H.1    Lehto, S.2    Salomaa, V.3
  • 4
    • 0032560807 scopus 로고    scopus 로고
    • Mortality from coronary heart disease in subjects with type 2 diabetes and in nondiabetic subjects with and without prior myocardial infarction
    • Haffner S.M., Lehto S., Ronnemaa T., Pyorala K., and Laakso M. Mortality from coronary heart disease in subjects with type 2 diabetes and in nondiabetic subjects with and without prior myocardial infarction. N Engl J Med 339 4 (Jul 23 1998) 229-234
    • (1998) N Engl J Med , vol.339 , Issue.4 , pp. 229-234
    • Haffner, S.M.1    Lehto, S.2    Ronnemaa, T.3    Pyorala, K.4    Laakso, M.5
  • 5
    • 0343036110 scopus 로고    scopus 로고
    • Influence of diabetes on 5-year mortality and morbidity in a randomized trial comparing CABG and PTCA in patients with multivessel disease: the Bypass Angioplasty Revascularization Investigation (BARI)
    • Influence of diabetes on 5-year mortality and morbidity in a randomized trial comparing CABG and PTCA in patients with multivessel disease: the Bypass Angioplasty Revascularization Investigation (BARI). Circulation 96 (1997) 1761-1769
    • (1997) Circulation , vol.96 , pp. 1761-1769
  • 6
    • 0033064073 scopus 로고    scopus 로고
    • Incidence and determinants of mortality and cardiovascular events in diabetes mellitus: a meta-analysis
    • Kanters S.D., Banga J.D., Stolk R.P., and Algra A. Incidence and determinants of mortality and cardiovascular events in diabetes mellitus: a meta-analysis. Vasc Med 4 2 (1999) 67-75
    • (1999) Vasc Med , vol.4 , Issue.2 , pp. 67-75
    • Kanters, S.D.1    Banga, J.D.2    Stolk, R.P.3    Algra, A.4
  • 7
    • 0026318602 scopus 로고
    • Detection of silent myocardial ischemia in diabetes mellitus
    • Langer A., Freeman M.R., Josse R.G., et al. Detection of silent myocardial ischemia in diabetes mellitus. Am J Cardiol 67 (1991) 1073-1078
    • (1991) Am J Cardiol , vol.67 , pp. 1073-1078
    • Langer, A.1    Freeman, M.R.2    Josse, R.G.3
  • 8
    • 0028049511 scopus 로고
    • Effect of autonomic nervous system on the circadian pattern of myocardial ischemia in diabetes mellitus
    • Zarich S., Waxman S., Freeman R.T., et al. Effect of autonomic nervous system on the circadian pattern of myocardial ischemia in diabetes mellitus. J Am Coll Cardiol 24 (1994) 956-962
    • (1994) J Am Coll Cardiol , vol.24 , pp. 956-962
    • Zarich, S.1    Waxman, S.2    Freeman, R.T.3
  • 9
    • 0342506484 scopus 로고    scopus 로고
    • Regulation of energy substrate metabolism in the diabetic heart
    • Stanley W.C., Lopaschuk G.D., and McCormack J.G. Regulation of energy substrate metabolism in the diabetic heart. Cardiovasc Res 34 1 (Apr 1997) 25-33
    • (1997) Cardiovasc Res , vol.34 , Issue.1 , pp. 25-33
    • Stanley, W.C.1    Lopaschuk, G.D.2    McCormack, J.G.3
  • 10
    • 0027958562 scopus 로고
    • Myocardial glucose transporters and glycolytic metabolism during ischemia in hyperglycemic diabetic swine
    • Stanley W.C., Hall J.L., Smith K.R., Cartee G.D., Hacker T.A., and Wisneski J.A. Myocardial glucose transporters and glycolytic metabolism during ischemia in hyperglycemic diabetic swine. Metabolism 43 1 (Jan 1994) 61-69
    • (1994) Metabolism , vol.43 , Issue.1 , pp. 61-69
    • Stanley, W.C.1    Hall, J.L.2    Smith, K.R.3    Cartee, G.D.4    Hacker, T.A.5    Wisneski, J.A.6
  • 11
    • 0031934256 scopus 로고    scopus 로고
    • Metabolic disturbances in diabetic cardiomyopathy
    • Rodrigues B., Cam M.C., and McNeill J.H. Metabolic disturbances in diabetic cardiomyopathy. Mol Cell Biochem 180 1-2 (Mar 1998) 53-57
    • (1998) Mol Cell Biochem , vol.180 , Issue.1-2 , pp. 53-57
    • Rodrigues, B.1    Cam, M.C.2    McNeill, J.H.3
  • 12
    • 0037199390 scopus 로고    scopus 로고
    • Impaired myocardial fatty acid oxidation and reduced protein expression of retinoid X receptor-alpha in pacing-induced heart failure
    • Osorio J.C., Stanley W.C., Linke A., et al. Impaired myocardial fatty acid oxidation and reduced protein expression of retinoid X receptor-alpha in pacing-induced heart failure. Circulation 106 5 (Jul 30 2002) 606-612
    • (2002) Circulation , vol.106 , Issue.5 , pp. 606-612
    • Osorio, J.C.1    Stanley, W.C.2    Linke, A.3
  • 13
    • 0342506484 scopus 로고    scopus 로고
    • Regulation of energy substrate metabolism in the diabetic heart
    • Stanley W.C., Lopaschuk G.D., and McCormack J.G. Regulation of energy substrate metabolism in the diabetic heart. Cardiovasc Res 34 1 (Apr 1997) 25-33
    • (1997) Cardiovasc Res , vol.34 , Issue.1 , pp. 25-33
    • Stanley, W.C.1    Lopaschuk, G.D.2    McCormack, J.G.3
  • 14
    • 0030297078 scopus 로고    scopus 로고
    • Increased cardiac fatty acid uptake with dobutamine infusion in swine is accompanied by a decrease in malonyl CoA levels
    • Hall J.L., Lopaschuk G.D., Barr A., Bringas J., Pizzurro R.D., and Stanley W.C. Increased cardiac fatty acid uptake with dobutamine infusion in swine is accompanied by a decrease in malonyl CoA levels. Cardiovasc Res 32 5 (Nov 1996) 879-885
    • (1996) Cardiovasc Res , vol.32 , Issue.5 , pp. 879-885
    • Hall, J.L.1    Lopaschuk, G.D.2    Barr, A.3    Bringas, J.4    Pizzurro, R.D.5    Stanley, W.C.6
  • 16
    • 0022239270 scopus 로고
    • Asymptomatic transient ST changes during ambulatory ECG monitoring in diabetic patients
    • Chiariello M., Indolfi C., Cotecchia M.R., Sifola C., Romano M., and Condorelli M. Asymptomatic transient ST changes during ambulatory ECG monitoring in diabetic patients. Am Heart J 110 (1985) 529-534
    • (1985) Am Heart J , vol.110 , pp. 529-534
    • Chiariello, M.1    Indolfi, C.2    Cotecchia, M.R.3    Sifola, C.4    Romano, M.5    Condorelli, M.6
  • 17
    • 0031567848 scopus 로고    scopus 로고
    • Prevalence of unrecognized silent myocardial ischemia and its association with atherosclerotic risk factors in noninsulindependent diabetes mellitus. Milan Study on Atherosclerosis and Diabetes (MiSAD) Group
    • MiSAD Study Group
    • MiSAD Study Group. Prevalence of unrecognized silent myocardial ischemia and its association with atherosclerotic risk factors in noninsulindependent diabetes mellitus. Milan Study on Atherosclerosis and Diabetes (MiSAD) Group. Am J Cardiol 79 (1997) 134-139
    • (1997) Am J Cardiol , vol.79 , pp. 134-139
  • 18
    • 0037014612 scopus 로고    scopus 로고
    • Significance of silent ischemia and microalbuminuria in predicting coronary events in asymptomatic patients with type 2 diabetes
    • Rutter M.K., Wahid S.T., McComb J.M., and Marshall S.M. Significance of silent ischemia and microalbuminuria in predicting coronary events in asymptomatic patients with type 2 diabetes. J Am Coll Cardiol 40 (2002) 56-61
    • (2002) J Am Coll Cardiol , vol.40 , pp. 56-61
    • Rutter, M.K.1    Wahid, S.T.2    McComb, J.M.3    Marshall, S.M.4
  • 20
    • 0022548123 scopus 로고
    • Asymptomatic myocardial ischemia in diabetes and its relationship to diabetic neuropathy: an exercise electrocardiography study in middle-aged diabetic men
    • Hume L., Oakley G.D., Boulton A.J., Hardisty C., and Ward J.D. Asymptomatic myocardial ischemia in diabetes and its relationship to diabetic neuropathy: an exercise electrocardiography study in middle-aged diabetic men. Diabetes Care 9 (1986) 384-388
    • (1986) Diabetes Care , vol.9 , pp. 384-388
    • Hume, L.1    Oakley, G.D.2    Boulton, A.J.3    Hardisty, C.4    Ward, J.D.5
  • 21
    • 0025292357 scopus 로고
    • Prevalence of asymptomatic myocardial ischaemia in diabetic subjects
    • Koistinen M.J. Prevalence of asymptomatic myocardial ischaemia in diabetic subjects. BMJ 301 (1990) 92-95
    • (1990) BMJ , vol.301 , pp. 92-95
    • Koistinen, M.J.1
  • 22
    • 0035142650 scopus 로고    scopus 로고
    • Predictive value of cardiac autonomic neuropathy in diabetic patients with or without silent myocardial ischemia
    • Valensi P., Sachs R.N., Harfouche B., et al. Predictive value of cardiac autonomic neuropathy in diabetic patients with or without silent myocardial ischemia. Diabetes Care 24 (2001) 339-343
    • (2001) Diabetes Care , vol.24 , pp. 339-343
    • Valensi, P.1    Sachs, R.N.2    Harfouche, B.3
  • 23
    • 3342948360 scopus 로고    scopus 로고
    • Detection of silent myocardial ischemia in asymptomatic diabetic subjects: the DIAD study
    • Wackers F.J., Young L.H., Inzucchi S.E., et al. Detection of silent myocardial ischemia in asymptomatic diabetic subjects: the DIAD study. Diabetes Care 27 (2004) 1954-1961
    • (2004) Diabetes Care , vol.27 , pp. 1954-1961
    • Wackers, F.J.1    Young, L.H.2    Inzucchi, S.E.3
  • 24
    • 0033990228 scopus 로고    scopus 로고
    • High incidence of silent myocardial ischemia in elderly patients with non insulin dependent diabetes mellitus
    • Inoguchi T., Yamashita T., Umeda F., et al. High incidence of silent myocardial ischemia in elderly patients with non insulin dependent diabetes mellitus. Diabetes Res Clin Pract 47 (2000) 37-44
    • (2000) Diabetes Res Clin Pract , vol.47 , pp. 37-44
    • Inoguchi, T.1    Yamashita, T.2    Umeda, F.3
  • 25
    • 0036676005 scopus 로고    scopus 로고
    • Assessment of asymptomatic coronary artery disease in apparently uncomplicated type 2 diabetic patients: a role for lipoprotein(a) and apolipoprotein(a) polymorphism
    • Gazzaruso C., Garzaniti A., Giordanetti S., et al. Assessment of asymptomatic coronary artery disease in apparently uncomplicated type 2 diabetic patients: a role for lipoprotein(a) and apolipoprotein(a) polymorphism. Diabetes Care 25 (2002) 1418-1424
    • (2002) Diabetes Care , vol.25 , pp. 1418-1424
    • Gazzaruso, C.1    Garzaniti, A.2    Giordanetti, S.3
  • 27
    • 0035131480 scopus 로고    scopus 로고
    • Silent coronary artery disease in diabetes: a feature of autonomic neuropathy or accelerated atherosclerosis?
    • Airaksinen K.E. Silent coronary artery disease in diabetes: a feature of autonomic neuropathy or accelerated atherosclerosis?. Diabetologia 44 (2001) 259-266
    • (2001) Diabetologia , vol.44 , pp. 259-266
    • Airaksinen, K.E.1
  • 28
    • 0021984563 scopus 로고
    • The value of cardiovascular autonomic function tests: 10 years experience in diabetes
    • Ewing D.J., Martyn C.N., Young R.J., and Clarke B.F. The value of cardiovascular autonomic function tests: 10 years experience in diabetes. Diabetes Care 8 (1985) 491-498
    • (1985) Diabetes Care , vol.8 , pp. 491-498
    • Ewing, D.J.1    Martyn, C.N.2    Young, R.J.3    Clarke, B.F.4
  • 29
    • 0019165516 scopus 로고
    • Primary myocardial disease, diabetes mellitus, and small vessel disease
    • Zoneraich S., Silverman G., and Zoneraich O. Primary myocardial disease, diabetes mellitus, and small vessel disease. Am Heart J 100 5 (Nov 1980) 754-755
    • (1980) Am Heart J , vol.100 , Issue.5 , pp. 754-755
    • Zoneraich, S.1    Silverman, G.2    Zoneraich, O.3
  • 30
    • 0342506484 scopus 로고    scopus 로고
    • Regulation of energy substrate metabolism in the diabetic heart
    • Stanley W.C., Lopaschuk G.D., and McCormack J.G. Regulation of energy substrate metabolism in the diabetic heart. Cardiovasc Res 34 1 (Apr 1997) 25-33
    • (1997) Cardiovasc Res , vol.34 , Issue.1 , pp. 25-33
    • Stanley, W.C.1    Lopaschuk, G.D.2    McCormack, J.G.3
  • 31
    • 0034678082 scopus 로고    scopus 로고
    • The antianginal drug trimetazidine shifts cardiac energy metabolism from fatty acid oxidation to glucose oxidation by inhibiting mitochondrial long-chain 3-ketoacyl coenzyme A thiolase
    • Kantor P.F., Lucien A., Kozak R., and Lopaschuk G.D. The antianginal drug trimetazidine shifts cardiac energy metabolism from fatty acid oxidation to glucose oxidation by inhibiting mitochondrial long-chain 3-ketoacyl coenzyme A thiolase. Circ Res 86 5 (Mar 17 2000) 580-588
    • (2000) Circ Res , vol.86 , Issue.5 , pp. 580-588
    • Kantor, P.F.1    Lucien, A.2    Kozak, R.3    Lopaschuk, G.D.4
  • 32
    • 0025110897 scopus 로고
    • Comparison of trimetazidine with nifedipine in effort angina: a double-blind crossover study
    • Dalla Volta S., Maraglino G., Della Valentina P., et al. Comparison of trimetazidine with nifedipine in effort angina: a double-blind crossover study. Cardiovasc Drugs Ther 4 (1990) 853-859
    • (1990) Cardiovasc Drugs Ther , vol.4 , pp. 853-859
    • Dalla Volta, S.1    Maraglino, G.2    Della Valentina, P.3
  • 33
    • 0028359703 scopus 로고
    • Trimetazidine: a new concept in the treatment of angina. Comparison with propranolol in patients with stable angina
    • Detry J.M., Sellier P., PennaLorte S., et al. Trimetazidine: a new concept in the treatment of angina. Comparison with propranolol in patients with stable angina. Br J Clin Pharmacol 37 (1994) 279-288
    • (1994) Br J Clin Pharmacol , vol.37 , pp. 279-288
    • Detry, J.M.1    Sellier, P.2    PennaLorte, S.3
  • 34
    • 0031028751 scopus 로고    scopus 로고
    • Antianginal efficacy of the combination of trimetazidine-propranolol compared with isosorbide dinitrate-propranolol in patients with stable angina
    • Michaelides A.P. Antianginal efficacy of the combination of trimetazidine-propranolol compared with isosorbide dinitrate-propranolol in patients with stable angina. Clin Drug Invest 13 (1997) 8-14
    • (1997) Clin Drug Invest , vol.13 , pp. 8-14
    • Michaelides, A.P.1
  • 35
    • 0033036313 scopus 로고    scopus 로고
    • The antiischemic effects and tolerability of trimetazidine in coronary diabetic patients. A substudy from TRIMPOL-I
    • Szwed H., Pachocki R., Domnzal-Bochenska M., et al. The antiischemic effects and tolerability of trimetazidine in coronary diabetic patients. A substudy from TRIMPOL-I. Cardiovasc Drugs Ther 13 (1999) 215-220
    • (1999) Cardiovasc Drugs Ther , vol.13 , pp. 215-220
    • Szwed, H.1    Pachocki, R.2    Domnzal-Bochenska, M.3
  • 36
    • 2542487307 scopus 로고    scopus 로고
    • The protective effect of trimetazidine on the myocardium against reperfusion injury during thrombolytic therapy of acute infarction
    • Rebrova T., Afanas'eva S.A., Perchatkin V.A., Maksimov I.V., and Markov V.A. The protective effect of trimetazidine on the myocardium against reperfusion injury during thrombolytic therapy of acute infarction. Eksp Klin Farmakol 67 2 (Mar-Apr 2004) 27-30
    • (2004) Eksp Klin Farmakol , vol.67 , Issue.2 , pp. 27-30
    • Rebrova, T.1    Afanas'eva, S.A.2    Perchatkin, V.A.3    Maksimov, I.V.4    Markov, V.A.5
  • 37
    • 10644245294 scopus 로고    scopus 로고
    • Trimetazidine and cardioprotection during ischemia-reperfusion
    • Barsotti A., and Di Napoli P. Trimetazidine and cardioprotection during ischemia-reperfusion. Ital Heart J 5 Suppl 2 (Mar 2004) 29S-36S
    • (2004) Ital Heart J , vol.5 , Issue.SUPPL. 2
    • Barsotti, A.1    Di Napoli, P.2
  • 38
    • 0346252380 scopus 로고    scopus 로고
    • Trimetazidine improves recovery during reperfusion in isolated rat hearts after prolonged ischemia
    • Ikizler M., Dernek S., Sevin B., and Kural T. Trimetazidine improves recovery during reperfusion in isolated rat hearts after prolonged ischemia. Anadolu Kardiyol Derg 3 4 (Dec 2003) 303-308
    • (2003) Anadolu Kardiyol Derg , vol.3 , Issue.4 , pp. 303-308
    • Ikizler, M.1    Dernek, S.2    Sevin, B.3    Kural, T.4
  • 39
    • 16644397430 scopus 로고    scopus 로고
    • Ischemic heart disease and left ventricular dysfunction: the role of trimetazidine
    • [Italian]
    • Belardinelli R. Ischemic heart disease and left ventricular dysfunction: the role of trimetazidine. Ital Heart J 5 Suppl 2 (Mar 2004) 23S-28S [Italian]
    • (2004) Ital Heart J , vol.5 , Issue.SUPPL. 2
    • Belardinelli, R.1
  • 40
    • 2942512039 scopus 로고    scopus 로고
    • Trimetazidine improves left ventricular function in diabetic patients with coronary artery disease: a double-blind placebo-controlled study
    • Rosano G.M., Vitale C., Sposato B., Mercuro G., and Fini M. Trimetazidine improves left ventricular function in diabetic patients with coronary artery disease: a double-blind placebo-controlled study. Cardiovasc Diabetol 2 1 (Nov 28 2003) 16
    • (2003) Cardiovasc Diabetol , vol.2 , Issue.1 , pp. 16
    • Rosano, G.M.1    Vitale, C.2    Sposato, B.3    Mercuro, G.4    Fini, M.5
  • 41
    • 1542496389 scopus 로고    scopus 로고
    • Short-and long-term beneficial effects of trimetazidine in patients with diabetes and ischemic cardiomyopathy
    • Fragasso G., Piatti Md.P.M., Monti L., et al. Short-and long-term beneficial effects of trimetazidine in patients with diabetes and ischemic cardiomyopathy. Am Heart J 146 5 (Nov 2003) E18
    • (2003) Am Heart J , vol.146 , Issue.5
    • Fragasso, G.1    Piatti, Md.P.M.2    Monti, L.3
  • 42
    • 4944224833 scopus 로고    scopus 로고
    • Trimetazidine improves left ventricular function and quality of life in elderly patients with coronary artery disease
    • Vitale C., Wajngaten M., Sposato B., et al. Trimetazidine improves left ventricular function and quality of life in elderly patients with coronary artery disease. Eur Heart J 25 20 (Oct 2004) 1814-1821
    • (2004) Eur Heart J , vol.25 , Issue.20 , pp. 1814-1821
    • Vitale, C.1    Wajngaten, M.2    Sposato, B.3
  • 43
    • 22244463240 scopus 로고    scopus 로고
    • Effects of trimetazidine on myocardial perfusion and the contractile response of chronically dysfunctional myocardium in ischemic cardiomyopathy: a 24-month study
    • El-Kadi T., El-Sabban K., Gabaly M., Sabry A., and Abdel-Hady S. Effects of trimetazidine on myocardial perfusion and the contractile response of chronically dysfunctional myocardium in ischemic cardiomyopathy: a 24-month study. Am J Cardiovasc Drug 5 4 (2005) 271-278
    • (2005) Am J Cardiovasc Drug , vol.5 , Issue.4 , pp. 271-278
    • El-Kadi, T.1    El-Sabban, K.2    Gabaly, M.3    Sabry, A.4    Abdel-Hady, S.5


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