Long- and short-term changes in the neuroimmune-endocrine parameters following inhalation exposures of F344 rats to low-dose sarin

Toxicological Sciences

Volumn 97, Issue 1, 2007, Pages 181-188

  Peña Philippides, Juan Carlos ^a   Razani Boroujerdi, Seddigheh ^a   Singh, Shashi P ^a   Langley, Raymond J ^a   Mishra, Neerad C ^a   Henderson, Rogene F ^a   Sopori, Mohan L ^a  

^a LOVELACE RESPIRATORY RESEARCH INSTITUTE   (United States)

Author keywords

Glucocorticoids; Hypothalamus pituitary adrenal (HPA) axis; Neuroimmune modulation; Organophosphates; Sarin

Indexed keywords

BIOLOGICAL MARKER; CALCIUM ION; CHLORISONDAMINE; CORTICOSTERONE; CORTICOTROPIN; CYTOKINE; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; MESSENGER RNA; SARIN; T LYMPHOCYTE RECEPTOR; CALCIUM; CHEMICAL WARFARE AGENT; CHOLINESTERASE INHIBITOR; GANGLION BLOCKING AGENT; LYMPHOCYTE ANTIGEN RECEPTOR;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIBODY PRODUCING CELL; ARTICLE; AUTONOMIC NERVOUS SYSTEM; CONTROLLED STUDY; ENZYME ACTIVATION; GENE EXPRESSION; HORMONE INHIBITION; HYPOTHALAMUS HYPOPHYSIS ADRENAL SYSTEM; IMMUNE RESPONSE; IMMUNOLOGICAL PARAMETERS; LONG TERM EXPOSURE; LUNG ALVEOLUS CELL; LUNG LAVAGE; LYMPHOCYTE FUNCTION; MALE; NONHUMAN; PNEUMONIA; PROTEIN EXPRESSION; RAT; RAT STRAIN; UPREGULATION; ANIMAL; BLOOD; CHEMICALLY INDUCED DISORDER; DRUG EFFECT; EXPOSURE; FISCHER 344 RAT; GENETIC TRANSCRIPTION; GENETICS; HYPOPHYSIS ADRENAL SYSTEM; HYPOTHALAMUS HYPOPHYSIS SYSTEM; IMMUNOMODULATION; INFLAMMATION; LUNG; METABOLISM; NEUROSECRETION; PATHOLOGY; T LYMPHOCYTE; TIME;

RATTUS;

ADRENOCORTICOTROPIC HORMONE; ANIMALS; AUTONOMIC NERVOUS SYSTEM; BIOLOGICAL MARKERS; CALCIUM; CHEMICAL WARFARE AGENTS; CHLORISONDAMINE; CHOLINESTERASE INHIBITORS; CORTICOSTERONE; CYTOKINES; GANGLIONIC BLOCKERS; HYPOTHALAMO-HYPOPHYSEAL SYSTEM; INFLAMMATION; INHALATION EXPOSURE; LUNG; MALE; NEUROIMMUNOMODULATION; NEUROSECRETORY SYSTEMS; NF-KAPPA B; PITUITARY-ADRENAL SYSTEM; RATS; RATS, INBRED F344; RECEPTORS, ANTIGEN, T-CELL; RNA, MESSENGER; SARIN; T-LYMPHOCYTES; TIME FACTORS; TRANSCRIPTION, GENETIC;

EID: 34347204911     PISSN: 10966080     EISSN: 10960929     Source Type: Journal    
DOI: 10.1093/toxsci/kfm017     Document Type: Article

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