Persistent nicotinic blockade by chlorisondamine of noradrenergic neurons in rat brain and cultured PC12 cells

British Journal of Pharmacology

Volumn 125, Issue 6, 1998, Pages 1218-1227

  Reuben, M ^a   Louis, M ^a   Clarke, P B S ^a  

^a MCGILL UNIVERSITY   (Canada)

Author keywords

Chlorisondamine; Dopamine; Glutamate receptors; Hippocampus; Nicotine; Nicotinic receptors; Noradrenaline; PC12 cells; Striatum; Synaptosomes

Indexed keywords

CHLORISONDAMINE; CYTISINE; MECAMYLAMINE; N METHYL DEXTRO ASPARTIC ACID; NICOTINE; NORADRENALIN;

ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; BRAIN; CELL STRAIN; HIPPOCAMPUS; INTRACEREBROVENTRICULAR DRUG ADMINISTRATION; LOCUS CERULEUS; MALE; NONHUMAN; NORADRENALIN RELEASE; NORADRENERGIC NERVE; NORADRENERGIC SYSTEM; PRIORITY JOURNAL; RAT; SUBCUTANEOUS DRUG ADMINISTRATION;

EID: 0031773772     PISSN: 00071188     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.bjp.0702215     Document Type: Article

References (42)

1. ALKADHI, K.A. & MCISAAC, R.J. (1974). Effect of preganglionic nerve stimulation on sensitivity of the superior cervical ganglion to nicotinic blocking agents. Br. J. Pharmacol., 51, 533-539.
2. ASTON-JONES, G., SHIPLEY, M.T. & GRZANNA, R. (1995). The locus coeruleus, α5 and α7 noradrenergic cell groups. In The Rat Nerrous System. 2nd edition; ed. Paxinos, G. pp. 183-213. New York: Academic Press.
3. BLUMENTHAL, E.M., CONROY, W.G., ROMANO, S.J., KASSNER, P.D. & BERG, D.K. (1997). Detection of functional nicotinic receptors blocked by bungarotoxin on PC12 cells and dependence of their expression on post-translational events. J. Neurosci., 17, 6094-6104.
4. BOWIE, D. & MAYER, M.L. (1995). Inward rectification of both AMPA and kainate subtype glutamate receptors generated by polyamine-mediated ion channel block. Neuron, 15, 453-462.
5. CLARKE, P.B.S. (1984). Chronic central nicotinic blockade after a single administration of the bisquaternary ganglion-blocking drug chlorisondamine. Br. J. Pharmacol., 83, 527-535.
6. CLARKE, P.B.S., CHAUDIEU, I., EL-BIZRI, H., BOKSA, P., QUIK, M., ESPLIN, B.A. & CAPEK, R. (1994a). The pharmacology of the nicotinic antagonist, chlorisondamine, investigated in rat brain and autonomic ganglion. Br. J. Pharmacol., 111, 397-405.
7. CLARKE, P.B.S., REUBEN, M. & EL-BIZRI, H. (1994b). Blockade of nicotinic responses by physostigmine, tacrine and other cholinesterase inhibitors in rat striatum. Br. J. Pharmacol., 111, 695-702.
8. CLARKE, P.B.S. & KUMAR, R. (1983). Characterization of the locomotor stimulant action of nicotine in tolerant rats. Br. J. Pharmacol., 80, 587-594.
9. → : Possible action at the dopamine transporter, Br. J. Pharmacol., 114, 315-322.
10. 3H]-dopamine release. Br. J. Pharmacol., 117, 595-606.
11. COLQUHOUN, L.M. & PATRICK, J.W. (1997). α3, β2, and β4 form heterotrimeric neuronal nicotinic acetylcholine receptors in Xenopus oocytes. J. Neurochem., 69, 2355-2362.
12. CORRIGALL, W.A., FRANKLIN, K.B.J., COEN, K.M. & CLARKE. P.B.S. (1992). The mesolimbic dopaminergic system is implicated in the reinforcing effects of nicotine. Psychopharmacology, 107, 285-289.
13. DALY, J.W., NISHIZAWA, Y., EDWARDS, M.W., WATERS, J.A. & ARONSTAM, R.S. (1991). Nicotinic receptor-elicited sodium flux in rat pheochromocytoma PC12 cells: Effects of agonists, antagonists, and noncompetitive blockers. Neurochem. Res., 16, 489-500.
14. DECKER, M.W., BUCKLEY, M.J. & BRIONI, J.D. (1994). Differentia: effects of pretreatment with nicotine and lobeline on nicotine-induced changes in body temperature and locomotor activity ir mice. Drug Dev. Res., 31, 52-58.
15. DUNNETT, C.W. (1955). A multiple comparison procedure for comparing several treatments with a control. J Amer. Statist. Assoc., 50, 1096-1121.
16. 3H]-chlorisondamine. Br. J. Pharmacol., 116, 2503-2509.
17. EL-BIZRI, H. & CLARKE, P.B.S. (1994a). Blockade of nicotinic receptor-mediated release of dopamine from striatal synaptosomes by chlorisondamine and other nicotinic antagonists administered in vitro. Br. J. Pharmacol., 111, 406-413.
18. EL-BIZRI, H. & CLARKE, P.B.S. (1994b). Blockade of nicotinic receptor-mediated release of dopamine from striatal synaptosomes by chlorisondamine administered in vivo. Br. J. Pharmacol., 111, 414-418.
19. EL-BIZRI, H. & CLARKE, P.B.S. (1994c). Regulation of nicotinic receptors in rat brain following quasi-irreversible nicotinic blockade by chlorisondamine and chronic treatment with nicotine. Br. J. Pharmacol., 113, 917-925.
20. GLANTZ, S.A. (1992). Primer of Biostatistics. 3rd edition; New York: McGraw-Hill.
21. 3H]dopamine release from mouse striatal synaptosomes. J. Neurochem., 62, 1390-1398.
22. 3H]norepinephrine from a clonal line of pheochromocytoma cells (PC12) by nicotinic cholinergic stimulation. Brain Res., 138, 521-528.
23. GREENE, L.A. & TISCHLER, A.S. (1976). Establishment of a noradrenergic clonal line of rat adrenal pheochromocytoma cells which respond to nerve growth factor. Proc. Natl. Acad. Sci. U.S.A., 73, 2424-2428.
24. KEMP, G. & EDGE, M. (1987). Cholinergic function and alpha-bungarotoxin binding in PC12 cells. Mol. Pharmacol., 32, 356-363.
25. KULAK, J.M., NGUYEN, T.A., OLIVERA, B.M. & MCINTOSH, J.M. (1997). Alpha-conotoxin MII blocks nicotine-stimulated dopamine release in rat striatal synaptosomes. J. Neurosci., 17, 5263-5270.
26. KUMAR, R., REAVILL, C. & STOLERMAN, I.P. (1987). Nicotine cue in rats: effects of central administration of ganglion-blocking drugs. Br. J. Pharmacol., 90, 239-246.
27. LE NOVERE, N., ZOLI, M. & CHANGEUX, J.P. (1996). Neuronal nicotinic receptor α6 subunit mRNA is selectively concentrated in catecholaminergic nuclei of the rat brain. Eur. J. Neurosci., 8, 2428-2439.
28. LUETJE, C.W. & PATRICK, J. (1991). Both alpha- and beta-subunits contribute to the agonist sensitivity of neuronal nicotinic acetylcholine receptors. J. Neurosci., 11, 837-845.
29. MUNDY, W.R. & IWAMOTO, E.T. (1988). Actions of nicotine on the acquisition of an autoshaped lever-touch response in rats. Psychopharmacology , 94, 267-274.
30. PAPKE, R.L. & HEINEMANN, S.F. (1994). Partial agonist properties of cytisine on neuronal nicotinic receptors containing the β2 subunit. Mol. Pharmacol., 45, 142-149.
31. PAXINOS, G. & WATSON, C. (1986). The Rat Brain in Stereotaxic Coordinates. 2nd edition; San Diego, CA: Academic Press.,
32. PITTALUGA, A. & RAITERI, M. (1990). Release-enhancing glycinedependent presynaptic NMDA receptors exist on noradrenergic terminals of hippocampus. Eur. J. Pharmacol., 191, 231-234.
33. PITTALUGA, A. & RAITERI, M. (1992). N-methyl-D-aspartic acid (NMDA) and non-NMDA receptors regulating hippocampal norepinephrine release. I. Location on axon terminals and pharmacological characterization. J. Pharmacol. Exp. Ther., 260, 232-237.
34. PLUMMER, A.J., TRAPOLD, J.H., SCHNEIDER, J.A., MAXWELL, R.A. & EARL, A.E. (1955). Ganglionic blockade by a new bisquaternary series, including chlorisondamine dimethochloride. J. Pharmacol. Exp. Ther., 115, 172-184.
35. RAMOA, A.S., ALKONDON, M., ARACAVA, Y., IRONS, J., LUNT, G.G., DESHPANDE, S.S., WONNACOTT, S., ARONSTAM, R.S. & ALBUQUERQUE, E.X. (1990). The anticonvulsant MK-801 interacts with peripheral and central nicotinic acetylcholine receptor ion channels. J. Pharmacol. Exp. Ther., 254, 71-82.
36. RAPIER, C., LUNT, G.G. & WONNACOTT, S. (1988). Stereoselective nicotine-induced release of dopamine from striatal synaptosomes: concentration dependence and repetitive stimulation. J. Neurochem., 50, 1123-1130.
37. REAVILL, C., STOLERMAN, I.P., KUMAR, R. & GARCHA, H.S. (1986). Chlorisondamine blocks acquisition of the conditioned taste aversion produced by (-)-nicotine. Neuropharmacology, 25, 1067-1069.
38. ROGERS, S.W., MANDELZYS, A., DENERIS, E.S., COOPER, E. & HEINEMANN, S. (1992). The expression of nicotinic acetylcholine receptors by PC12 cells treated with NGF. J. Neurosci., 12, 4611-4623.
39. SIVILOTTI, L.G., MCNEIL, D.K., LEWIS, T.M., NASSAR, M.A., SCHOEPFER, R. & COLQUHOUN, D. (1997). Recombinant nicotinic receptors, expressed in Xenopus oocytes, do not resemble native rat sympathetic ganglion receptors in single-channel behaviour. J. Physiol. (Lond.), 500, 123-138.
40. STRONG, S.E., CAGGIULA, A.R., SAYLOR, S. & PLOSKINA, T.M. (1997). Time course of the selective peripheral antagonism of nicotine by chlorisondamine. Soc. Neurosci. Abstr., 23, 103.9
41. WANG, F., GERZANICH, V., WELLS, G.B., ANAND, R., PENG, X., KEYSER, K. & LINDSTROM, J. (1996). Assembly of human neuronal nicotinic receptor α5 subunits with α3, β2, and β4 subunits. J. Biol. Chem., 271, 17656-17665.
42. WONG, E.T., HOLSTAD, S.G., MENNERICK, S.J., HONG, S.E., ZORUMSKI, C.F. & ISENBERG, K.E. (1995). Pharmacological and physiological properties of a putative ganglionic nicotinic receptor, α3β4, expressed in transfected eucaryotic cells. Brain Res. Mol. Brain Res., 28, 101-109.